Differential neutron energy spectra measured on spacecraft in low earth orbit

Dudkin, V.E.; Potapov, Yu.V.; Akopova, A.B.; Melkumyan, L.V.; Benton, E. V.; Frank, A.L.

doi:10.1016/1359-0189(90)90188-4

Cited by 34 publications

(2 citation statements)

References 10 publications

(1 reference statement)

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“…A main cause of cell death induced by high-LET radiation is non-reparable double strand DNA breaks which are produced at a higher rate compared to low-LET irradiation [3]. In humans, exposure to neutrons can occur during nuclear fission reactions usually associated with the production of nuclear energy and cosmic radiation in the environment [1,2,5]. Consequently, it is very important to study the direct effects of neutrons on human organs and tissues to precisely ascertain the risk of high-LET radiation exposure.…”

Section: Introductionmentioning

confidence: 99%

Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice

Yang

Kim

et al. 2012

J Vet Sci

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Object recognition memory and contextual fear conditioning task performance in adult C57BL/6 mice exposed to cranial fast neutron irradiation (0.8 Gy) were examined to evaluate hippocampus-related behavioral dysfunction following acute exposure to relatively low doses of fast neutrons. In addition, hippocampal neurogenesis changes in adult murine brain after cranial irradiation were analyzed using the neurogenesis immunohistochemical markers Ki-67 and doublecortin (DCX). In the object recognition memory test and contextual fear conditioning, mice trained 1 and 7 days after irradiation displayed significant memory deficits compared to the sham-irradiated controls. The number of Ki-67- and DCX-positive cells decreased significantly 24 h post-irradiation. These results indicate that acute exposure of the adult mouse brain to a relatively low dose of fast neutrons interrupts hippocampal functions, including learning and memory, possibly by inhibiting neurogenesis.

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Section: Introductionmentioning

confidence: 99%

Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice

Yang

Kim

et al. 2012

J Vet Sci

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“…Cosmic radiation interacting with the Earth's atmosphere continuously generates neutrons. [10][11][12][13][14][15] The cosmic rays (essentially 85% of Hydrogen and 12.5% of Helium) penetrate the magnetic fields of the solar system and the Earth, and as they reach the Earth's atmosphere, they collide with atomic nuclei in the air (78% Nitrogen, 21% Oxygen and 1% Argon) to create cascades of secondary radiation of every kind. The intensity and energy distribution of different particles that make up atmospheric cosmic radiation vary in 3 essential parameters: altitude, location in the geomagnetic field (correlated to latitude, it deflects low-momentum charged particles back into space), and time in the sun's magnetic activity cycle.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic potential of atmospheric neutrons

Voyant

Roustit²,

Tatje³

et al. 2011

Reports of Practical Oncology & Radiotherapy

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It has been shown that BNCT may be used with a natural source of neutrons, and may potentially be useful for the treatment of micro-metastases. The atmospheric neutron flux is much lower than that utilized during standard NBCT. However the purpose of the proposed study is not to replace the ordinary NBCT but to test if naturally occurring atmospheric neutrons, considered to be an ionizing pollution at the Earth's surface, can be used in the treatment of a disease such as cancer. To finalize this study, it is necessary to quantify the biological effects of the physically deposited dose, taking into account the characteristics of the incident particles (alpha particle and Lithium atom) and radio-induced effects (by-stander and low dose effect). One of the aims of the presented paper is to propose to experimental teams (which would be interested in studying the phenomena) a simple way to calculate the dose deposition (allometric fit of free path, transmission factor of brain).

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