Object recognition memory and contextual fear conditioning task performance in adult C57BL/6 mice exposed to cranial fast neutron irradiation (0.8 Gy) were examined to evaluate hippocampus-related behavioral dysfunction following acute exposure to relatively low doses of fast neutrons. In addition, hippocampal neurogenesis changes in adult murine brain after cranial irradiation were analyzed using the neurogenesis immunohistochemical markers Ki-67 and doublecortin (DCX). In the object recognition memory test and contextual fear conditioning, mice trained 1 and 7 days after irradiation displayed significant memory deficits compared to the sham-irradiated controls. The number of Ki-67- and DCX-positive cells decreased significantly 24 h post-irradiation. These results indicate that acute exposure of the adult mouse brain to a relatively low dose of fast neutrons interrupts hippocampal functions, including learning and memory, possibly by inhibiting neurogenesis.
Non-rail mobile rack, which is used for cargo storage, can improve the storage capacities of logistics centers. Furthermore, it has the advantage that it can be used in traditional logistics centers without making any changes or renovation, such as installing rails. However, when the rack is operated by separated drive actuators mounted on the left and the right wheels, precise position control of the wheels is necessary even if the unbalanced cargo weight on the rack would affect the control. Therefore, internal synchronization control for position tracking between the left and right wheels on the non-rail mobile rack is necessary in this study. In addition, external synchronization control for realizing the same straight movements between mobile racks is necessary. For the internal and the external synchronization control, we propose a synchronization control algorithm based on the repetitive control theory. An internal synchronization control algorithm with repetitive control theory requires the application of the robust servo control method owing to parameter variations. In this case, we can set up the gains for the robust servo control system by considering the cargo variations on the mobile rack. Furthermore, for developing the external synchronization control algorithm, we use a double repetitive control system to perform synchronization control between mobile racks. The efficiency of the proposed control algorithm will be verified by simulation and experimental results. The proposed algorithm can be easily applied in the industry.
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