Differential features of carotid and vertebral artery dissections

Debette, Stéphanie; Grond‐Ginsbach, Caspar; Bodenant, Marie; Kloß, Manja; Engelter, Stefan T.; Metso, Tiina M.; Pezzini, Alessandro; Brandt, Tobias; Caso, Valeria; Touzé, Emmanuel; Metso, Antti J.; Canaple, Sandrine; Abboud, Shérine; Giacalone, Giacomo; Lyrer, Philippe; Zotto, Elisabetta Del; Giroud, Maurice; Samson, Yves; Dallongeville, Jean; Tatlısumak, Turgut; Leys, Didier; Martin, Juan J.

doi:10.1212/wnl.0b013e31822f03fc

Cited by 200 publications

(210 citation statements)

References 41 publications

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“…Stroke of other determined cause, predominantly cervical artery dissections 19, 21, has been described as the second most frequent cause of stroke in the young. In our study, the proportion of this subtype declined steeply during mid‐age and was non‐existent among the elderly.…”

Section: Discussionmentioning

confidence: 99%

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study

et al. 2015

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ObjectivesAge dependency of acute ischaemic stroke aetiology and vascular risk factors have not been adequately evaluated in stroke patients in Norway. Aims of this study were to evaluate how stroke subtypes and vascular risk factors vary with age in a western Norway stroke population.Materials and methodsPatients aged 15–100 years consecutively admitted to our neurovascular centre with acute ischaemic stroke between 2006 and 2012 were included. The study population was categorized as young (15–49 years), middle‐aged (50–74 years) or elderly (≥75 years). Stroke aetiology was defined by TOAST criteria. Risk factors and history of cardiovascular disease were recorded.ResultsIn total, 2484 patients with acute cerebral infarction were included: 1418 were males (57.3%). Mean age was 70.8 years (SD ± 14.9), 228 patients were young, 1126 middle‐aged, and 1130 were elderly. The proportion of large‐artery atherosclerosis and of small‐vessel occlusion was highest among middle‐aged patients. The proportion of cardioembolism was high at all ages, especially among the elderly. The proportion of stroke of other determined cause was highest among young patients. Some risk factors (diabetes mellitus, active smoking, angina pectoris, prior stroke and peripheral artery disease) decreased among the elderly. The proportions of several potential causes increased with age.ConclusionThe proportion of stroke subtypes and vascular risk factors are age dependent. Age 50–74 years constitutes the period in life where cardiovascular risk factors become manifest and stroke subtypes change.

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Section: Discussionmentioning

confidence: 99%

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study

et al. 2015

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“…5 In light of these new findings, we aimed to compare the frequency of potential risk factors, presenting clinical characteristics, and outcome after 3 months in patients with sICAD and sVAD. Furthermore, we investigated whether time to diagnosis differed between sVAD and sICAD and changed over time.…”

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confidence: 99%

Differences and Similarities Between Spontaneous Dissections of the Internal Carotid Artery and the Vertebral Artery

Babo

Marchis

Sarıkaya

et al. 2013

Stroke

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“…Причина некроза миоцитов осталась не-установленной, однако наличие в некоторых участ-ках адвентиции лимфоцитарных и эозинофильных инфильтратов, а также обнаружение эпителиоидно-клеточной гранулемы позволяет предполагать ин-фекцию, провоцирующая роль которой для разви-тия диссекции хорошо известна. У 11-22% боль-ных, по собственным и данным литературы, диссек-ции предшествует банальная инфекция [16][17][18]. Предполагается, что она сопровождается повыше-нием уровня протеолитических ферментов, которые вызывают деградацию белков экстраклеточного ма-трикса, что снижает прочность сосудистой стенки [19].…”

Section: Discussionunclassified

Internal carotid artery dissection as a cause of severe ischemic stroke with lethal outcome

Калашникова

Chaykovskaya

Добрынина

et al. 2015

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Differential features of carotid and vertebral artery dissections

Abstract: In the largest published series of patients with CEAD, we observed significant differences between VAD and ICAD in terms of risk factors, baseline features, and functional outcome.

Cited by 200 publications

References 41 publications

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study

Age dependency of ischaemic stroke subtypes and vascular risk factors in western Norway: the Bergen Norwegian Stroke Cooperation Study

Differences and Similarities Between Spontaneous Dissections of the Internal Carotid Artery and the Vertebral Artery

Internal carotid artery dissection as a cause of severe ischemic stroke with lethal outcome

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