Differential encoding of place value between the dorsal and intermediate hippocampus

Abstract

Differential encoding of place value between the dorsal and intermediate hippocampusHighlights d Place cells in the intermediate hippocampus remap instantly upon value change d Place cells in the intermediate hippocampus overrepresent high-value locations d Value-based remapping is rarely observed in place cells in the dorsal hippocampus

Space, feature, and risk sensitivity in homing pigeons (Columba livia): Broadening the conversation on the role of the avian hippocampus in memory

“…An impaired ability of HF-lesioned pigeons to use differential reward probabilities has been demonstrated elsewhere (Scarf et al, 2014). Our results are also consistent with previous studies related to goal-directed spatial behavior that suggested rodents with inactivated hippocampi routinely seek out stable, reliable, and constant reward-related outcomes compared to variable or risker options (Mizumori & Tyron, 2015;Mizumori et al, 2009;Mizumori et al, 2004;Wiener, 1993), as well as the more general observation of reward properties influencing hippocampal representations of space (Jeong et al, 2018; Jin & Lee, 2021;Jung et al, 2018;Sosa & Giocomo, 2021;Wood et al, 2000).…”

“…Even in a species that does not cache food, what is interesting about the relationship between the homing pigeon HF and spatial memory for food locations is that it implies some modulation of HF-dependent spatial representations by the experience of reward. Indeed, in the mammalian hippocampus literature, there is a growing recognition that hippocampal-dependent spatial maps are influenced by the spatial distribution and properties of reward occurrence (Jeong et al, 2018;Jin & Lee, 2021;Jung et al, 2018;Mamad et al, 2017;Mizumori & Tyron, 2015;Mizumori et al, 2009;Mizumori et al, 2004;Penner & Mizumori, 2012;Retailleau et al, 2012;Tryon et al, 2017;Wiener, 1993;Wood et al, 2000; see Sosa & Giocomo, 2021, for a review). Similarly, avian HF-dependent spatial representations also appear strongly influenced by how rewards are distributed in space.…”

Distinct spatial maps and multiple object codes in the lateral entorhinal cortex

“…Spatial firing of neurons in the LEC was less evident in previous studies in standard open field settings, but based on the published histological data it can be inferred that the recording sites were mostly in the posterior LEC 19,20,[22][23][24][25]28,53 . Spatial selectivity gradients have been reported also for the hippocampus and the MEC 35,[54][55][56] , and may reflect both a gradient of gene expression and local cellular connectivity as well as different inputs from upstream regions. At this point it can only be speculated as to whether the spatial selectivity gradient can be accounted for, at least in part, by differential inputs in LEC.…”

The Hippocampal Horizon: Constructing and Segmenting Experience for Episodic Memory

“…Such reward-associated cells were context-dependent or context-invariant to the external virtual environment and the reward-predictive neurons were correlated with slowed running behaviour indictive of reward anticipation (Gauthier & Tank, 2018). Moreover, shifting of intermediate CA1 place field locations were observed in response to palatable changes in reward value (Jin & Lee, 2021). Again, such reward-location activation is not unique to rodents but can also be seen in other species (e.g., Pigeons; Bingman & Sharp, 2006).…”