Differential Diagnosis Cyanosis Versus Argyria: When Your Patient Remains Blue—A 48-year-old Trauma Patient With Persistent Cyanosis

Travis, Christina

doi:10.1016/j.jen.2009.12.021

Journal of Emergency Nursing

2010

DOI: 10.1016/j.jen.2009.12.021

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Differential Diagnosis Cyanosis Versus Argyria: When Your Patient Remains Blue—A 48-year-old Trauma Patient With Persistent Cyanosis

Christina Travis

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2021

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“…[1,8,20,36,40,43,45,53,56,66,69,131,169,178,200,245,246,248,[252][253][254][255][256] Nevus Flat or raised pigmented skin lesion (LA)[2,71,73,76,82,133,137,164,229,…”

mentioning

confidence: 99%

Clinical and Forensic Aspects of the Different Subtypes of Argyria

Mota

Dinis-Oliveira

2021

JCM

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Argyria encompasses the different cosmetic alterations that can develop if enough silver particles deposit in a specific tissue, typically in the skin, ranging from localized dark-blue macules to a generalized slate-gray/bluish tinge following systemic absorption. This work aims to fully review the state of the art regarding pathophysiology, diagnosis, treatment, and relevant clinical and forensic features of argyria. Argyria has been diagnosed in a wide range of ages, both sexes and varied ethnicities, with no known individual predisposing factors. Ultraviolet radiation with subsequence increases of melanin production aggravates the discoloration due to a reduction in the silver deposits. Physical examination and silver exposure in the anamnesis can be highly suggestive of the diagnosis, but a histopathological analysis with Energy-Dispersive X-ray Spectroscopy is required to unequivocally determine the discoloration etiology. Safe and effective treatment has only been accomplished with laser techniques, though only a few cases have been reported and with limited follow-up time. In conclusion, argyria typically has an occupational or iatrogenic etiology. It should be suspected when a patient presents with typical skin or eye lesions. A seemingly viable treatment modality, with laser technology, is finally within the horizon.

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“…[1,8,20,36,40,43,45,53,56,66,69,131,169,178,200,245,246,248,[252][253][254][255][256] Nevus Flat or raised pigmented skin lesion (LA)[2,71,73,76,82,133,137,164,229,…”

mentioning

confidence: 99%

Clinical and Forensic Aspects of the Different Subtypes of Argyria

Mota

Dinis-Oliveira

2021

JCM

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When self-medication goes wrong: the case of argyria at the Padua Morgagni Museum of Pathology

et al. 2021

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Differential Diagnosis Cyanosis Versus Argyria: When Your Patient Remains Blue—A 48-year-old Trauma Patient With Persistent Cyanosis

Cited by 2 publications

References 3 publications

Clinical and Forensic Aspects of the Different Subtypes of Argyria

Clinical and Forensic Aspects of the Different Subtypes of Argyria

When self-medication goes wrong: the case of argyria at the Padua Morgagni Museum of Pathology

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