Different effects of nano- and microplastics on oxidative status and gut microbiota in the marine medaka Oryzias melastigma

Kang, Hye-Min; Byeon, Eunjin; Jeong, Haksoo; Kim, Min‐Sub; Chen, Qiqing; Lee, Jae‐Seong

doi:10.1016/j.jhazmat.2020.124207

Cited by 155 publications

(48 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…30 Due to the delicate balance between the endogenous intestinal microbiota and their natural reservoirs, 72,73 the altered microbial communities by pollutants could lead to intestinal inflammation and diseases in fish. 20,74 Rhodobacter sp. can improve the innate immunity of fish and are often added in fish diet for growth enhancement.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…18 This intestinal barrier can be impaired by pollutants, leading to inflammatory responses and altering the membrane permeability in animals, thereby causing potential risk to the fish health. 19,20 In the past decade, the association of altered gut microbiota with the health of animals including humans has gained increasing attention. 21,22 Gut microbiota are essential for nutritional absorption and healthy maintenance in animals, including the prevention of colonization of infectious agents, promotion of nutrient supply, maintenance of energy homeostasis, and normal mucosal immune function.…”

Section: ■ Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dietary Seleno-l-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka Oryzias latipes

Liu

Xiao

Lei

et al. 2021

Environ. Sci. Technol.

View full text Add to dashboard Cite

Excess dietary seleno-l-methionine (Se-Met) induces various adverse effects in fish inhabiting the Se-contaminated environments. However, there is an extreme paucity of data on the effects of excess dietary Se-Met on the microbiota in the gastrointestinal (GI) tract in fish. In this study, Japanese medaka Oryzias latipes (three months old) were fed the Se-Met enriched diets at environmentally relevant concentrations: 2.90 (Control: (C), 6.69 (L), 11.89 (M), and 27.05 (H) μg Se/g dw) for 60 d. Histopathological, high throughput sequencing, and biochemical approaches were used to investigate the alterations in histology and microbial communities of the GI tract, enzymatic activity, and transcripts of closely related genes. The results showed that the fish weight was reduced at ∼13% from the L and H treatments. Decreased height and thickness of villus in the GI tract were observed in the H treatment. Meanwhile, the level of D-lactate and activity of diamine oxidase (DAO), protease, and lipase were inhibited in the H treatment. The transcripts of the genes related to the inflammation (i.e., IL-1β and IL-8) were elevated, while those of the genes related to the intestinal barrier (i.e., cdh1, ZO-1, ocln, and cldn7) were inhibited in the H treatment. In addition, alpha diversity at the genus level was higher in the L treatment than the control, and the composition of the microbial community was altered by dietary Se-Met. Furthermore, 5 genera (Rhodobacter, Cloacibacterium, Bdellovibrio, Shinella, and Aeromonas) exhibited the largest variation in abundance among treatments. This study has demonstrated that excess dietary Se-Met inhibits growth, causes hispathological damage to the GI tract, and alters the composition of the microbial community in Oryzias latipes.

show abstract

Section: ■ Results and Discussionmentioning

confidence: 99%

Section: ■ Introductionmentioning

confidence: 99%

Dietary Seleno-l-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka Oryzias latipes

Liu

Xiao

Lei

et al. 2021

Environ. Sci. Technol.

View full text Add to dashboard Cite

show abstract

“…In the zebrafish gut, it was observed a significant alteration in the microbial community after exposure to MPs. These alterations were likely mediated by inflammation and oxidative stress ( 112 – 114 ). At the phylum level, the increased count of Proteobacteria was accompanied by a significant reduction in the count of Fusobacteria, Firmicutes , and Verrucomicrobiota after 21-day exposure to 1 mg/L of MPs ( 72 ).…”

Section: Bidirectional Interaction Between Environmental Chemicals An...mentioning

confidence: 99%

Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction

et al. 2022

View full text Add to dashboard Cite

There is a growing interest in the characterization of the involvement of toxicant and pollutant exposures in the development and the progression of several diseases such as obesity, diabetes, cancer, as well as in the disruption of the immune and reproductive homeostasis. The gut microbiota is considered a pivotal player against the toxic properties of chemicals with the establishment of a dynamic bidirectional relationship, underlining the toxicological significance of this mutual interplay. In fact, several environmental chemicals have been demonstrated to affect the composition, the biodiversity of the intestinal microbiota together with the underlining modulated metabolic pathways, which may play an important role in tailoring the microbiotype of an individual. In this review, we aimed to discuss the latest updates concerning the environmental chemicals–microbiota dual interaction, toward the identification of a distinctiveness of the gut microbial community, which, in turn, may allow to adopt personalized preventive strategies to improve risk assessment for more susceptible workers.

show abstract

“…Moreover, nanoplastic, but not microplastic, increased the activity of antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT), in the gut and induced apoptosis detected as DNA breaks. However, microparticulate PS affected microbiota composition more significantly than nanoparticulate PS, mainly by decreasing the abundance of Bacteroidetes [ 50 ]. These results indicate that the effects provoked by MNPs are size-specific and that NPs may be more prone to disturb the redox balance, while MPs cause a more pronounced dysbiosis.…”

Section: Impact Of Nanoplastic Exposure On the Gut-brain Axismentioning

confidence: 99%

Nanoplastic Impact on the Gut-Brain Axis: Current Knowledge and Future Directions

Grodzicki

Dziendzikowska

Gromadzka-Ostrowska

et al. 2021

IJMS

View full text Add to dashboard Cite

The widespread usage of plastic places a significant burden on the environment and impacts numerous aquatic and terrestrial species. Humans in particular can be affected by plastic pollution, predominantly via inhalation and ingestion, as well as trophic transfer along the food chain. Under natural conditions synthetic materials undergo degradation into micro- and nanoparticles, especially prone to interact with biological systems. Organisms exposed to nanoplastic accumulate it in multiple tissues, including the gut and the brain. This phenomenon raises a question about the impact of nanoparticulate plastics on the communication pathways between these organs. The aim of this review is to explore an unsettling possibility of the influence of nanoplastic on the gut-brain axis and provide a comprehensive summary of available data regarding this subject. The scarce but consistent evidence shows that exposure to plastic nanoparticles can indeed affect both the digestive and the nervous system. Reported outcomes include microbiota alterations, intestinal barrier permeability, oxidative stress, inflammation, neurotoxicity and behavioral disturbances. Taking into consideration these alarming observations and the ubiquitous presence of plastics in human environment, more research is urgently needed in order to identify any potential threats that nanoplastic exposure can pose to the functioning of the gut-brain axis.

show abstract

Different effects of nano- and microplastics on oxidative status and gut microbiota in the marine medaka Oryzias melastigma

Cited by 155 publications

References 62 publications

Dietary Seleno-l-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka Oryzias latipes

Dietary Seleno-l-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka Oryzias latipes

Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction

Nanoplastic Impact on the Gut-Brain Axis: Current Knowledge and Future Directions

Contact Info

Product

Resources

About