Different Blood Groups; Association With Body Mass Index in Medical Students of Karachi

Abstract

ABSTRACT… Objectives: To find out the association of body mass index with different blood groups in medical students. Background: Increased body mass index leads to obesity and is a prominent risk factor for hypertension and diabetes. Blood groups are known to be associated with various diseases and recent studies have shown that a particular blood group with the highest body mass index appeared to be more susceptible to predisposition to hypertension. Study Design: Cross-sectional study. Setting: Liaquat National Medical College, Karachi. Period: June 2015 to September 2015. Methodology: 181 medical students with 85 males and 96 females and age ranging from 18-22 years. Weight and height of each student was measured using the standard stadiometer and blood groups were determined using the antisera. Results: Mean age of the participants was 19.92 ± 1.10 years. Blood group "O" was found to be most prevalent (39.2%) while blood group "AB" was found to be the least (8.3%). Mean BMI of subjects with blood group A, B, AB and O were found to be 24.3 ± 5.04, 22.6 ± 3.59, 23.0 ± 2.91 and 23.7 ± 4.20 kg/m 2 respectively. The highest BMI was found in subjects with blood group "A" 24.3 ± 5.04 kg/m 2 and lowest in blood group "AB" 23.0 ± 2.91kg/m 2 . The Rhesus-D positive and male students had greater body mass index 23.6 ± 3.56 than females 23.2 ± 3.44. Comparison of overall mean BMI values among different blood groups showed significant difference with p-value < 0.001. Conclusion: Blood group "A" and Rhesus-D positive subjects especially males were found to be the high risk blood type with predisposition to morbidity associated with increased body mass index. Key words:Blood groups, body mass index, medical students. Article Citation: Parveen N, Rehman J, Hassan SH, Hassan Z, Rehman M. Different blood groups; association with body mass index in medical students of Karachi.

Retrospective study of frequency of ABO and Rhesus blood group among population of Safdarabad and Faisalabad cities of Pakistan

“…Other studies from twin cities Islamabad and Rawalpindi [28], Gujranwala [29], Lahore [30], Mirpur [31] and Multan [32] reflects the same result like presented in this study of Safdarabad. The current findings of Faisalabad city where blood group O is found the most common is in agreement with the studies conducted in Multan [32], Karachi [33], and Gujrat [34] cities ( Table 3).…”

“…The current findings of Faisalabad city where blood group O is found the most common is in agreement with the studies conducted in Multan [ 32 ], Karachi [ 33 ], and Gujrat [ 34 ] cities (Table 3 ).…”

Association of ABO Blood Group and Body Mass Index: A Cross-Sectional Study from a Ghanaian Population

“…This trend of result is similar to the report from studies by Acquaye [ 49 ] in Ghana and Eru et al [ 50 ] in Nigeria. Also, studies by Bhatti et al [ 51 ] in India and Parveen et al [ 30 ] as well as Bhattacharyya et al [ 52 ] in Pakistan have reported similar ABO blood group pattern. Worldwide distribution pattern has shown blood type O to be the most prevalent blood group followed by group B, group A, and group AB [ 53 ], which is consistent with the findings in this present study.…”

“…Reports in literature on the relationship between ABO blood group and BMI are inconsistent [ 38 , 56 ], with various authors associating increased BMI with the presence of particular ABO antigens, while others have shown no association between these two factors. Significant association was seen between ABO blood group and BMI among sampled populations from Pakistan [ 30 ], India [ 33 , 34 , 38 ], Malaysia [ 31 , 32 ], Nigeria [ 35 ], and Denmark [ 40 ]. One may be tempted to assume that ABO blood type and body weight may be biologically related probably through a pathway that involves thrombotic factors like FVIII because it is known for example, that non-blood group O individuals have higher FVIII.…”

How good is the obesity associated with blood groups in a cohort of female university going students?

“… 4 Several researchers in the past have reported the linkage of obesity with ABO blood groups, 4 , 5 while some have also disagreed to this relation. 2 , 6 Evidences are also present suggesting the ABO system as a genotype marker for obesity 7 but this relationship is still under intense investigation due to these conflicting results. New studies are needed to validate the association between blood groups and BMI, as the curiosity in this matter is unabated.…”