Different approaches of katira gum formulations for colon targeting

Physicochemical properties and release characteristics of starches from seeds of Indian Shahi Litchi

“…This may be due to the variation in chemical composition of the isolated starch. Amylose content contributes to the high water holding capacity whereas amylopectin contributes to retardation of dissolution of drug [36]. LN and LC starch containing tablets showed 42.25-58.95% and 53.43-67.18% of drug released in 5 h. respectively.…”

Enhancement of anti-inflammatory activity of glycyrrhizic acid by encapsulation in chitosan-katira gum nanoparticles

“…Katira gum is a non-toxic, anionic natural polysaccharide isolated from Cochlospermum religiosum [25] which has been recently reported as novel suitable pharmaceutical excipient [26]. It has also been proposed as a suitable carrier for colon targeting as it is resistant to acidic pH in stomach but is susceptible to degradation by colonic bacterial enzymes [27,28]. Nanoparticulate delivery system composed of chitosan-katira gum may not only control the rate of drug release but also improve its oral bioavailability and enhance its absorption.…”

Characterization and evaluation of smart starch from Kyllinga nemoralis

“…Release studies were compared with the marketed maize starch and it was found that there is complete release within 5 h in case of maize starch. From the release data it can be attributed that increase in amount of starch is capable of shielding the drug release fully in physiological environment of the small intestine when compared with maize starch [43]. It was thought that an improved swelling power of the matrix would enhance the drug permeability due to a larger space between the matrix chains whereas decreasing swelling will reduce it.…”