The article demonstrates the impact of digitalization security on implementation of modernengineering technologies, substantiates their connections with provision of the strategic economic security of anenterprise, presents enhanced methods of assessing the current economic-information security of an enterprise’sinterests. The developed methods of digitalization security assessment have been tested at machine buildingenterprises of Ukraine. The security level has proved to be medium or low at most enterprises under study. Thework substantiates that absence of the systematic personnel policy aimed at personnel’s acquiring competences4.0, deficit of financing technologies 4.0 implementation, a low level of IT capital make it impossible to ensurea high level of strategic economic security at Ukraine’s machine building enterprises.