Differences in organization between acute and chronic atrial fibrillation in dogs

Sih, Haris J.; Zipes, Douglas P.; Berbari, Edward J.; Adams, David; Olgin, Jeffrey E.

doi:10.1016/s0735-1097(00)00788-9

Cited by 90 publications

(55 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[2], [6] and [9] Alcaraz et al [2] and [6] demonstrated that persistent AF is associated with higher AFSE, that is, a more irregular atrial signal, than paroxysmal AF. This is consistent with invasive findings in humans 10 and dogs, 3 which also demonstrated a greater disorganization in the atrial activity in persistent AF than in paroxysmal AF.…”

Section: Methodological Issuessupporting

confidence: 91%

“…1 The term AF organization is generally defined as how repetitive the AF signal pattern is, 2 and it has been proposed that there is an association between the number of coexisting atrial wavelets and AF organization, with fewer wavelets correlating with a higher degree of organization. 3 Means to noninvasively assess atrial electrical remodeling have been presented. One is by measuring the AF rate (AFR), which correlates to the atrial refractory period 4 and thus, theoretically, to the degree of atrial electrical remodeling.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Noninvasive estimation of organization in atrial fibrillation as a predictor of sinus rhythm maintenance

Petersson

Sandberg

Platonov

et al. 2011

Journal of Electrocardiology

View full text Add to dashboard Cite

Previous studies indicate that the predictive value of atrial fibrillatory rate in patients undergoing cardioversion of atrial fibrillation (AF) of long duration is limited. The present study investigates signal entropy in this setting. Standard 12-lead electrocardiograms (ECGs) were recorded from 66 consecutive patients with AF undergoing cardioversion and sample entropy estimated. Patients were followed for 4 weeks. At follow-up, 59% of the patients had relapsed to AF. The AF signal entropy of these patients before cardioversion was 0.099 ± 0.015, whereas it was 0.093 ± 0.012 among the 41% maintaining sinus rhythm (P = .02). As hypothesized, signal entropy was lower in patients who maintained sinus rhythm 4 weeks after cardioversion than in those who did not. However, the overlap was large, making its clinical value limited.

show abstract

Section: Methodological Issuessupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Noninvasive estimation of organization in atrial fibrillation as a predictor of sinus rhythm maintenance

Petersson

Sandberg

Platonov

et al. 2011

Journal of Electrocardiology

View full text Add to dashboard Cite

show abstract

“…Morillo et al 12 described faster frequencies in the LA compared with the RA in a canine model of rapid atrial pacing-induced AF. Sih and colleagues, 13 also using the canine rapid atrial pacing model, examined differences between acute and persistent AF. They noted an LA-to-RA frequency gradient in both acute and persistent AF, with faster frequencies noted in both the RA and LA during persistent compared with acute AF.…”

Section: Discussionmentioning

confidence: 99%

Presence of Left-to-Right Atrial Frequency Gradient in Paroxysmal but Not Persistent Atrial Fibrillation in Humans

et al. 2004

View full text Add to dashboard Cite

Background— Recent studies have demonstrated spatiotemporal organization in atrial fibrillation (AF), with a left-to-right atrial frequency gradient during AF in isolated sheep hearts. We hypothesized that human AF would also manifest a left-to-right atrial frequency gradient. Methods and Results— Thirty-one patients aged 56.7±10.5 years with a history of paroxysmal or persistent (>1 month) AF were included. Recordings were made at each pulmonary vein (PV) ostium and simultaneously from the coronary sinus (CS) and posterior right atrium (RA) during AF. Sequential fast Fourier transforms (FFTs) were performed. FFT profiles were analyzed to determine the dominant frequency (DF). There were 18 patients with paroxysmal AF and 13 with persistent AF. In the paroxysmal group, there was a significant left-to-right atrial DF gradient, with DF highest at the PV/left atrial (LA) junction, intermediate at the CS, and lowest in the RA (6.2±0.8, 5.5±0.7, and 5.1±0.6 Hz, respectively; P <0.001). There were no patients in whom DF was greater at the RA than the PV/LA junction. In the persistent group, there was no significant difference between DF recorded from the LA/PV junction, CS, and RA (6.1±0.7, 5.8±0.6, and 5.8±0.6 Hz, respectively; P =NS). Conclusions— In humans with paroxysmal AF, DFs are highest at the PV/LA junction, intermediate in the CS, and slowest in the posterior RA. These findings agree with animal models that suggest that the posterior LA may play an important role in maintaining paroxysmal AF. The role of the posterior LA in persistent AF requires further study.

show abstract

“…The algorithm was theoretically extensible to account for non-linear relationships between electrograms by simply altering the nature of the adaptive filters. This group used the algorithm to quantify organization differences between acute and chronic models of atrial fibrillation [59].…”

Section: Invasive Organization Methodsmentioning

confidence: 99%

Applications of Signal Analysis to Atrial Fibrillation

Rieta¹,

Alcaraz²

2013

Atrial Fibrillation - Mechanisms and Treatment

View full text Add to dashboard Cite

Differences in organization between acute and chronic atrial fibrillation in dogs

Cited by 90 publications

References 37 publications

Noninvasive estimation of organization in atrial fibrillation as a predictor of sinus rhythm maintenance

Noninvasive estimation of organization in atrial fibrillation as a predictor of sinus rhythm maintenance

Presence of Left-to-Right Atrial Frequency Gradient in Paroxysmal but Not Persistent Atrial Fibrillation in Humans

Applications of Signal Analysis to Atrial Fibrillation

Contact Info

Product

Resources

About