Differences among admitting departments in alerts and alert overrides for drug–drug interaction

Abstract

Admitting department was an independent risk factor for alerts and alert overrides. Strategies to reduce alerts and alert overrides should consider the admitting department.

Decrease in use of contraindicated drugs with automated alerts in children

“…Moreover, it is also plausible that children and adolescents with severe cases visit tertiary hospitals and require contraindicated drugs. According to prior research, the incidence of drug–drug interactions and the rate of alert overrides rate varied by admitting department at a tertiary teaching hospital in Korea . Similarly, the alert override rate varied by clinical specialty at a teaching hospital in Taiwan …”

“…According to prior research, the incidence of drug-drug interactions and the rate of alert overrides rate varied by admitting department at a tertiary teaching hospital in Korea. 25 Similarly, the alert override rate varied by clinical specialty at a teaching hospital in Taiwan. 26 The predicted monthly number of users of drugs announced as age-contraindicated on 3 December 2009 showed a downward trend, suggesting that the use of the drugs had already started declining even before the announcement.…”

Optimizing Drug-Drug Interaction Alerts Using a Multidimensional Approach

“…Override rates and reasons for overriding can also vary across departments within a single institution and across alert types. 22,31,32 Metrics that can provide more information on appropriateness and value, such as alert adherence rate, 9,10 require increased clinician insight and cannot be easily obtained from an automated report. Other metrics have been recently introduced but need additional refinement.…”

Evaluation of an intravenous preparation information system for improving the reconstitution and dilution process

“…In the surgery group, the trend of PRRs in the IPIS_R period and the level of PRRs immediately after providing dilution information significantly changed, in contrast to the findings with the non-surgery group. We suggest that the physicians of the surgery department reacted to the alert more positively and rapidly and then ignored the alert in EMR [40][41][42]. However, more studies to determine the reasons underlying these differences are required.…”

“…However, we speculated that the doctors might have assumed that reconstitution solutions for IV preparation have a low impact on the clinical outcomes of the patients and, therefore, ignored the repeated alerts in the EMR [36,[40][41][42][43][44].…”