Decrease in use of contraindicated drugs with automated alerts in children

Song, Inmyung; Shin, Han Na; Shin, Ju‐Young

doi:10.1111/ped.13258

Cited by 5 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The decrease in outpatient prescriptions suggests that the increase in the antibiotic rate can also be attributable to a shift in the drug utilization review policy in Korea that discourages prescriptions of many other drugs in pediatric patients. 17 In the present study, the usage of antibiotics fluctuated from year to year. The trend of antibiotic usage may have been affected by external factors.…”

Section: Discussionmentioning

confidence: 67%

“…Between 2010 and 2014, the number of antibiotic prescriptions increased while that of outpatient prescriptions decreased, contributing to the rise in the antibiotic rate. The decrease in outpatient prescriptions suggests that the increase in the antibiotic rate can also be attributable to a shift in the drug utilization review policy in Korea that discourages prescriptions of many other drugs in pediatric patients …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Increased use of third‐generation cephalosporin antibiotics in the outpatient setting in Korean children and adolescents

Song

Park

Byun

et al. 2018

Pediatrics International

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Increased use of third‐generation cephalosporin antibiotics in the outpatient setting in Korean children and adolescents

Song

Park

Byun

et al. 2018

Pediatrics International

Self Cite

View full text Add to dashboard Cite

show abstract

“…The summary of characteristics of all the studies finally included was provided in Table 1. All included studies [18][19][20][21][22][23][24][25][26][27][28] evaluated the effects of the DUR system implemented in Korea, and the majority of study data used in these studies were Health Insurance Review and Assessment Service (HIRA) data. SO Kim et al 21) study analyzed National Health Insurance Service (NHIS) data to evaluate the DUR system, which were directly linked with HIRA data.…”

Section: Study Descriptionmentioning

confidence: 99%

“…These three studies showed the effects of implementing DUR system on the trend of pharmaceutical expenditures without indicating specific types of medications they analyzed. Two studies 19,22) found contraindicated use trends for drug-drug interactions after implementation of DUR system, and six studies 19,[23][24][25]27,28) described outcomes related to age-contraindicated drug uses. SO Lee et al, 19) JH Yang et al, 25) JH Heo et al 18) studies provided the outcomes after the DUR system implemented.…”

Section: Study Descriptionmentioning

confidence: 99%

“…SO Lee et al study 19) indicated number of alerts to avoid contraindicated drug uses and rates accepted by clinicians, which showed no reductions after DUR system initiated. Included studies 19,23,24,27,28) provided the trend of prescribing age-contraindicated medications showed reduction of drug uses after implementing the DUR system. The relative reduction of contraindicated drug uses was shown from 27.77 to 94.55%, and absolute reduction was from 1.80 to 4.54%.…”

Section: Trends Of Contraindicated Drug Usementioning

confidence: 99%

See 1 more Smart Citation

The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review

Lee

Choi

2019

Korean J Clin Pharm

View full text Add to dashboard Cite

prescribing drugs, avoiding contraindicated drug use is the most essential factor. 4-6) Furthermore, contraindicated drug uses were attributed to increase expenditures by additional hospital admissions. 2) Considering the risk for mortality increased by 40% with inappropriate exposure to contraindicated drugs for some vulnerable patients, 6) ensuring effective implementation of DUR system is important for the clinical and economic aspects. Nevertheless, some researchers reported current DUR system has yet to reach its full potential. 7-9) These reports initially questioned about the important discrepancy between current practice and potential advantages from drug utilization review, which showed that critical drug interactions were not detected ABSTRACT Objective: The objective of the present study was to evaluate the effects of implementing a systematic Drug Utilization Review (DUR) system on contraindicated drug use and pharmaceutical expenditures in Korea. Methods: A literature search was conducted using search engines such as PubMed, EMBASE, NDSL, and RISS for relevant systematic studies. The database search was performed and updated in April 2018. Two independent reviewers evaluated the abstracts to find potentially eligible articles. Results: In total, 1433 potentially eligible studies were selected, and 11 articles were eventually shortlisted for inclusion in the present review system. The outcome showed that contraindicated drug use decreased after implementation of the DUR system in Korea. The analysis also showed that the DUR system contributed to a reduction in pharmaceutical expenditures. Conclusions: Our study showed that implementing the DUR system reduced both contraindicated drug use and pharmaceutical expenditures in Korea.

show abstract

Effect of providing drug utilization review information on tricyclic antidepressant prescription in the elderly

et al. 2018

View full text Add to dashboard Cite

Tricyclic antidepressants are known as potentially inappropriate medications in the elderly. A notification issued in July 2015 in South Korea recommended caution while prescribing tricyclic antidepressants to the elderly. Further, since October 2015, the nationwide computerized drug utilization review monitoring system provides a pop-up window, on a real-time basis, whenever tricyclic antidepressants are prescribed to elderly outpatients. Therefore, we evaluated whether providing drug utilization review information was effective in reducing tricyclic antidepressant prescription to elderly outpatients. We used the Health Insurance Review and Assessment Service-Adult Patient Sample data from 2014 to 2016. Data related to the prescription of tricyclic antidepressants to outpatients aged 65 years or more were extracted. We determined the number of prescriptions per day per 100,000 elderly patients in each month, compared the average number of prescriptions before and after the drug utilization review information was provided, and evaluated the changes in the number of prescriptions by using an interrupted time series analysis. The average number of tricyclic antidepressant prescriptions per day per 100,000 elderly patients decreased from 76.6 (75.5 to 77.6) to 65.7 (64.5 to 66.9), a 14.2% reduction after the provision of drug utilization review information started. Following initiation of provision of drug utilization review information, there was an immediate drop of 9.2 tricyclic antidepressant prescriptions per day per 100,000 elderly patients, whereas there was no statistically significant change in trends. Providing the drug utilization review information on tricyclic antidepressant prescription for the elderly contributed to the reduction in tricyclic antidepressant prescriptions.

show abstract

Decrease in use of contraindicated drugs with automated alerts in children

Abstract: Decreases in contraindicated drugs have accelerated after a regulatory action with automated alerts.

Cited by 5 publications

References 25 publications

Increased use of third‐generation cephalosporin antibiotics in the outpatient setting in Korean children and adolescents

Increased use of third‐generation cephalosporin antibiotics in the outpatient setting in Korean children and adolescents

The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review

Effect of providing drug utilization review information on tricyclic antidepressant prescription in the elderly

Contact Info

Product

Resources

About