Difference in Atherosclerosis between the Populations of a Fishing and a Farming Village in Japan<sup>a</sup>

Yamada, Takayasu; Malcom, Gray T.; Strong, Jack P.; Ishii, Toshiharu; Ueno, Tomio; Koyama, Mamoru; Wagayama, Hidetaka; Shimizu, Atsuya; Sakai, Takahisa; Kyotani, Shingo; Tsushima, Motoo; Nakamori, Takako

doi:10.1111/j.1749-6632.1997.tb52021.x

Cited by 6 publications

(2 citation statements)

References 9 publications

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“…It is noteworthy that, as in previous reports, 9,10 higher rates of central obesity and of the unfavorable glucose and lipid metabolic profiles associated with central obesity were observed in the fishing communities compared to the farming communities. This may have been due to the customary diet in the fishing communities, which includes large amounts of fish protein and a high caloric intake of fish oil.…”

Section: Discussionmentioning

confidence: 61%

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Yano

Hoshide

Tamaki³

et al. 2011

American Journal of Hypertension

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Section: Discussionmentioning

confidence: 61%

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Yano

Hoshide

Tamaki³

et al. 2011

American Journal of Hypertension

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“…sclerosis and provides important prognostic information [57]. A cross-sectional study compared the IMT in Japanese resident of a fishing village or a farming village and demonstrated that individuals with greater dietary intake of ω-3 PUFA had significantly thinner IMT than those with lower intake [58]. Similar evaluation was done in an American cohort where individuals were subdivided according to α-linolenic acid intake with evidence, in unadjusted analysis, of significantly thinner IMT in people consuming greater amounts of this fatty acid [59].…”

Section: Mechanisms By Which ω-3 Pufa Affect Atherosclerosismentioning

confidence: 99%

Omega-3 Fatty Acids: from Biochemistry to their Clinical Use in the Prevention of Cardiovascular Disease

Colussi¹,

Catena²,

Baroselli³

et al. 2007

PRC

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Omega-3 and omega-6 Polyunsaturated fatty acids (PUFA) are the major families of PUFA that can be found as components of the human diet. After ingestion, both omega-3 and omega-6 PUFA are distributed to every cell in the body where they are involved in a myriad of physiological processes, including regulation of cardiovascular, immune, hormonal, metabolic, neuronal, and visual functions. At the cell level, these effects are mediated by changes in membrane phospholipids structure, interference with eicosanoid intracellular signaling, and regulation of gene expression. Two long-chain omega-3 PUFAs, the docosahexaenoic (DHA) and eicosapentaenoic (EPA) acid, are found in fatty fish and other marine sources and might be the putative dietary components thought to modify the cardiovascular risk in subjects consuming high amounts of such food. Evidence of an inverse relationship between fatty fish intake and cardiovascular risk has, in fact, emerged in studies performed more than twenty years ago in Eskimos and has been subsequently confirmed in other ethnic groups. The benefits of omega-3 PUFA might relate principally to prevention of coronary heart disease, coronary artery restenosis after angioplasty, and sudden arrhythmic death. In this brief review, we will cover the general biochemical aspects of omega-3 PUFA, summarize the evidence relating these fatty acids with control of cardiovascular risk factors and prevention of cardiovascular events, and overview the most recent and relevant patents that are related to these issues. More specifically, we will deal with the possibility to use PUFA in association with other molecules that can potentiate their antiinflammatory and antiatherogenic effects.

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Effects of omega-3 fatty acids on coronary restenosis, intima–media thickness, and exercise tolerance: A systematic review

et al. 2006

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Difference in Atherosclerosis between the Populations of a Fishing and a Farming Village in Japan^a

Cited by 6 publications

References 9 publications

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Omega-3 Fatty Acids: from Biochemistry to their Clinical Use in the Prevention of Cardiovascular Disease

Effects of omega-3 fatty acids on coronary restenosis, intima–media thickness, and exercise tolerance: A systematic review

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Difference in Atherosclerosis between the Populations of a Fishing and a Farming Village in Japana

Cited by 6 publications

References 9 publications

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Regional Differences in Hypertensive Cardiovascular Remodeling Between Fishing and Farming Communities in Japan

Omega-3 Fatty Acids: from Biochemistry to their Clinical Use in the Prevention of Cardiovascular Disease

Effects of omega-3 fatty acids on coronary restenosis, intima–media thickness, and exercise tolerance: A systematic review

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Product

Resources

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Difference in Atherosclerosis between the Populations of a Fishing and a Farming Village in Japan^a