“…Our research also identified a novel association between Bifidobacterium and elevated levels of LysoPI, a lysophosphatidylinositol potentially implicated in immune and inflammatory responses, as suggested by its links to conditions like asthma, COVID-19, and cervical inflammation in existing literature ( Zhang et al., 2018 ; Gu et al., 2022 ; Tu et al., 2024 ). Furthermore, the relevance of phospholipid metabolism, particularly LysoPI, in PPD pathophysiology, underscores the potential of dietary interventions, such as ϵ-polylysine supplementation, to influence gut microbiota and blood metabolite profiles, offering promising avenues for PPD prevention and treatment ( Zhang et al., 2022 ).…”