Dietary Uptake in Pike (Esox Lucius) of Some Polychlorinated Biphenyls, Polychlorinated Naphthalenes and Polybrominated Diphenyl Ethers Administered in Natural Diet

Abstract

Abstract-The dietary uptake of 12 halogenated diaromatic compounds was studied using northern pike (Esox lucius L.) fed with rainbow trout (Oncorhynchus mykiss (Walbaum)). Before the trout were fed to the pike, they had been injected with a cocktail of five polychlorinated biphenyls, four polychlorinated naphthalenes, and three polybrominated diphenyl ethers, dissolved in rainbow trout lipid. The reported uptake efficiencies (E) were in the range 35 to 90% and differ in some respect from earlier studies. The E-values for those substances with effective cross sections (ECS) Ͼ9.5 Å were considerably higher than expected if the membrane permeation at dietary uptake was restricted as proposed previously in the literature. There was no hydrophobicity dependency of the total dietary uptake efficiency as suggested by an earlier proposed empirical model. The difference between the results presented here and earlier studies is likely to depend on cotransport with lipids and/or proteins through a mediated, possibly active uptake of hydrophobic organic compounds (HOC) in the gastrointestinal tract enabled by the actual exposure method. For the proposed mediated/active uptake of HOCs, the uptake efficiency varied with molecular weight and was greatest for a molecular weight of approximately 450.

Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology.

“…Also, components of commercial "tetraBDE" (41% BDE-47; 45% BDE-99, 7% hexa-and 7-8% unknown PBDEs) are considered accumulative (6). An inverse relation was shown between the uptake efficiency and number of bromine atoms in pike when tetra (BDE-47), penta (BDE-99), and hexa (BDE-153) congeners were studied (56). The uptake efficiency of BDE-47 was over 90% and thus the highest of all the studied organohalogens.…”

Sorption of PBDE in low‐density polyethylene film: Implications for bioavailability of BDE‐209

“…Limited data on dietary uptake of PBDEs have been acquired through laboratory studies [5][6][7][8][9]23] and are summarized in Table S4. For northern pike (Esox lucius), dietary uptake efficiency decreases singly from BDE-47 (92 AE 20%) to BDE-99 (62 AE 10%) and to BDE-153 (40 AE 10%) [23] with increasing log K OW (Table 1). Common carp (Cyprinus carpio) also shows the same decreasing trend for BDE-47, -99, and -153, but a maxima occurs at BDE-47 (log K OW ¼ 6.80) when BDE-28, -183, and -209 are also included (Fig.…”

On-site and off-site atmospheric PBDEs in an electronic dismantling workshop in south China: Gas-particle partitioning and human exposure assessment

“…Fumes and ashes not only pollute the water, air, and soil, but also endanger the workers and residents due to flourished waste from many unorganized backyard workshops. PBDEs are prone to adsorption onto particulate matter, bioaccumulation, and biomagnification in the food chain due to their high affinity for lipids (Burreau et al, 1997). The toxicological endpoints of concern for environmental levels of PBDEs are likely to be thyroid hormone disruption, neuro-developmental deficit, and cancer (Burreau et al, 1997;McDonald, 2002).…”

“…PBDEs are prone to adsorption onto particulate matter, bioaccumulation, and biomagnification in the food chain due to their high affinity for lipids (Burreau et al, 1997). The toxicological endpoints of concern for environmental levels of PBDEs are likely to be thyroid hormone disruption, neuro-developmental deficit, and cancer (Burreau et al, 1997;McDonald, 2002). PBDE pollution has been confirmed from recent studies that have observed PBDEs in a variety of environmental matrices, including water (Xu et al, 2009), soil Yang et al, 2008), sediment (Leung et al, 2006;Wong et al, 2007), air Li et al, 2008), fish ,and human blood Qu et al, 2007;Roosens et al, 2010).…”