Dietary Supplements: Types, Health Benefits, Industry and Regulation

Hassan, Sadia; Egbuna, Chukwuebuka; Tijjani, Habibu; Ifemeje, Jonathan C.; Olisah, Michael Chinedu; Patrick-Iwuanyanwu, Kingsley C.; Onyeike, Precious Chidinma; Ephraim-Emmanuel, Benson Chukwunweike

doi:10.1007/978-3-030-42319-3_3

Cited by 13 publications

(11 citation statements)

References 48 publications

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“…Dietary supplements, including vitamins, minerals, proteins, herbs, probiotics, carbohydrates, hormone activators, and oil supplements are intended to improve an individual’s health status and well-being. They are taken during meals or at specific intervals to supplement an individual’s daily diet, especially when there is an imbalance in a nutrient or the absence of a specific nutrient [ 66 ]. Therefore, the Food and Drug Administration (FDA) and other international health organizations have established guidelines for the safety and efficacy of dietary supplements for medical use.…”

Section: Natural Products and Dietary Supplements For Afb1-induced Ki...mentioning

confidence: 99%

Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy

Ofori-Attah,

Hashimoto,

Oki

et al. 2024

IJMS

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Aflatoxins are harmful natural contaminants found in foods and are known to be hepatotoxic. However, recent studies have linked chronic consumption of aflatoxins to nephrotoxicity in both animals and humans. Here, we conducted a systematic review of active compounds, crude extracts, herbal formulations, and probiotics against aflatoxin-induced renal dysfunction, highlighting their mechanisms of action in both in vitro and in vivo studies. The natural products and dietary supplements discussed in this study alleviated aflatoxin-induced renal oxidative stress, inflammation, tissue damage, and markers of renal function, mostly in animal models. Therefore, the information provided in this review may improve the management of kidney disease associated with aflatoxin exposure and potentially aid in animal feed supplementation. However, future research is warranted to translate the outcomes of this study into clinical use in kidney patients.

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Section: Natural Products and Dietary Supplements For Afb1-induced Ki...mentioning

confidence: 99%

Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy

Ofori-Attah,

Hashimoto,

Oki

et al. 2024

IJMS

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“…Los suplementos alimenticios con mayor demanda son aquellos que contienen vitaminas, minerales, aminoácidos, enzimas y fitoquímicos. Estos se presentan de forma individual o mezclas de ellos, los cuales pueden provenir de extractos herbales o bien de síntesis química o aislando y purificando los compuestos de interés (Hassan et al, 2020;Lordan, 2021).…”

Section: Introductionunclassified

Potencial antioxidante y biofuncional de suplementos alimenticios de origen botánico mediante análisis in vitro e in silico

Jiménez-Ortega,

López-Romero,

Heredia-Bátiz

et al. 2024

rbio

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Los suplementos alimenticios y/o remedios herbolarios pueden coadyuvar a minimizar la aparición de patologías, sin embargo, son necesarios estudios funcionales y toxicológicos para determinar su eficacia y posible toxicidad. El objetivo de la presente investigación fue evaluar el potencial antioxidante y biofuncional de suplementos alimenticios, hechos a base de extractos botánicos. Para esto se determinó la capacidad antioxidante, capacidad reductora total, contenido de flavonoides totales y toxicidad in vitro. Además, se identificaron los compuestos orgánicos volátiles mediante cromatografía de gases acoplado a espectrometría de masas y se evaluó su biofuncionalidad mediante estudios bioinformáticos. Se observó el potencial antioxidante de los suplementos, debido al contenido de compuestos con capacidad reductora total, además de su aporte de terpenos, ácidos grasos (ácido hexadecanoico) y fitoesteroles. El producto con mayor actividad antioxidante no presentó toxicidad en el modelo de Artemia salina. El estudio in silico arrojó que los posibles objetivos de los compuestos en el organismo se encuentren relacionados con la inhibición de la patogénesis de algunas de las enfermedades crónico-degenerativas con mayor incidencia y prevalencia en México como la diabetes e hipertensión.

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“…Common types of food supplementation formulations are listed below [ 36 , 37 , 38 , 39 , 40 , 41 ]: Multivitamins: These formulations contain a combination of essential vitamins and minerals to support general health; their aim is to provide a comprehensive range of nutrients that may be lacking in a person’s diet. Omega-3 fatty acids: Omega-3 supplements often come in the form of fish oil or algae oil capsules.…”

Section: Introductionmentioning

confidence: 99%

Microbial Secondary Metabolites via Fermentation Approaches for Dietary Supplementation Formulations

Rusu¹,

Trif

Rocha

2023

Molecules

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Food supplementation formulations refer to products that are designed to provide additional nutrients to the diet. Vitamins, dietary fibers, minerals and other functional compounds (such as antioxidants) are concentrated in dietary supplements. Specific amounts of dietary compounds are given to the body through food supplements, and these include as well so-called non-essential compounds such as secondary plant bioactive components or microbial natural products in addition to nutrients in the narrower sense. A significant social challenge represents how to moderately use the natural resources in light of the growing world population. In terms of economic production of (especially natural) bioactive molecules, ways of white biotechnology production with various microorganisms have recently been intensively explored. In the current review other relevant dietary supplements and natural substances (e.g., vitamins, amino acids, antioxidants) used in production of dietary supplements formulations and their microbial natural production via fermentative biotechnological approaches are briefly reviewed. Biotechnology plays a crucial role in optimizing fermentation conditions to maximize the yield and quality of the target compounds. Advantages of microbial production include the ability to use renewable feedstocks, high production yields, and the potential for cost-effective large-scale production. Additionally, it can be more environmentally friendly compared to chemical synthesis, as it reduces the reliance on petrochemicals and minimizes waste generation. Educating consumers about the benefits, safety, and production methods of microbial products in general is crucial. Providing clear and accurate information about the science behind microbial production can help address any concerns or misconceptions consumers may have.

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Dietary Supplements: Types, Health Benefits, Industry and Regulation

Cited by 13 publications

References 48 publications

Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy

Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy

Potencial antioxidante y biofuncional de suplementos alimenticios de origen botánico mediante análisis in vitro e in silico

Microbial Secondary Metabolites via Fermentation Approaches for Dietary Supplementation Formulations

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