Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes

Burris, Ramona L.; Xie, Cheng-Hui; Thampi, Prajitha; Wu, Xianli; Melnyk, Stepan; Nagarajan, Shanmugam

doi:10.1016/j.atherosclerosis.2010.05.018

Cited by 34 publications

(24 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…101) Reduced atherosclerotic lesions were observed in aortic sinus and en face analyses of the descending aorta in RPI-fed apoEÀ/À mice as compared to casein-fed mice. Plasma total-and HDL-cholesterol levels were not different among the two groups.…”

Section: Nuclear Hormone Receptorsmentioning

confidence: 97%

Diet and Atherosclerosis in Apolipoprotein E-Deficient Mice

Imaizumi

2011

Bioscience, Biotechnology, and Biochemistry

View full text Add to dashboard Cite

Atherosclerosis is a multifactorial, long-lasting process in humans. Accordingly, animal models in which more rapid changes occur can be useful for the study of this process. Among such models are apolipoprotein E-deficient (apoE-/-) mice, which give insight into the human process. ApoE-/- mice show impaired clearing of plasma lipoproteins and develop atherosclerosis in a short time, and hence they are an excellent model in which to assess the impact of dietary factors. This review considers lipid metabolism and inflammation as well as nutritional constituents affecting atherosclerosis, with reference to apoE-/- mice, and discusses the mechanisms through which they act.

show abstract

Section: Nuclear Hormone Receptorsmentioning

confidence: 97%

Diet and Atherosclerosis in Apolipoprotein E-Deficient Mice

Imaizumi

2011

Bioscience, Biotechnology, and Biochemistry

View full text Add to dashboard Cite

show abstract

“…Their nutritional value is related to certain hypoallergenic properties, balanced amino acid content and good protein digestibility (Fiocchi, Travaini, D'Auria, Banderali, Bernado & Riva, 2003). Furthermore, some studies have shown that certain rice proteins exhibit hypocholesterolemic properties, antiatherosclerotic properties and inhibitory properties against particular cancer cells, suggesting that they have potential as a functional food (Burris, Xie, Thampi, Wu, Melnuk &Nagarajan, 2010 andTong et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Characterization of rice starch and protein obtained by a fast alkaline extraction method

et al. 2016

View full text Add to dashboard Cite

“…Diseases related to oxidative stress and aging have been reported in 97 of 114 acatalasemics (the inherited near-total deficiency of catalase activity) [51]. Moreover, increased levels of CAT activity have been reported to attenuate atherosclerosis in apoE-deficient mice [52]. Our results, therefore, indicate the potential of B. angulata juice in diminishing the risk of atherosclerosis, in part, by improving CAT activity which could result in reduced foam cell formation, an early event during atherosclerosis [53].…”

Section: Discussionmentioning

confidence: 98%