Dietary patterns and risk of gastric cancer: a case-control study in Uruguay

Abstract

This study displayed consistent results from three different approaches. Concerning different food groups, stewed and processed meat are rich in salt; rice, tubers, and winter squash are sources of starch; and vegetables and fruits are rich in ascorbic acid and carotenoids. All these substances have been strongly related to gastric carcinogenesis. Furthermore, this study suggests that diets rich in vegetables and fruits and with low amounts of salty and starchy foods are recommendable for the prevention of gastric cancer.

Coffee, black tea and risk of gastric cancer

“…Results from epidemiological studies on gastric cancer were inconsistent, with case-control ones suggesting, if any, a protective effect of coffee on gastric carcinogenesis [2][3][4][5], and some, but not all [1,2], cohort studies possibly suggesting an increased risk of gastric cancer in relation to coffee consumption [6][7][8]. However, none of the risk estimates provided by prospective studies were adjusted for several possible confounders, including tobacco smoking.…”

“…Black tea was inversely related to gastric cancer risk in case-control studies from India [11], Sweden [12], Poland [13], and Uruguay [5]. However, at least seven cohort studies from the USA [7,14], northern Europe [15,16], and Japan [1,17,18] found no clear association.…”

“…Two case-control studies from South America found a significant inverse association with coffee drinking [4,5], the odds ratios (OR) for the highest versus the lowest level of coffee consumption being 0.58 (95% confidence interval, CI: 0.37-0.92) [4] and 0.42 (95% CI: 0.25-0.68) [5], respectively. Conversely, two prospective studies, including 162 cases of gastric cancer from the Netherlands [6] and 108 Japanese cases resident in the Hawaii [7], found a modest positive association of borderline significance [2], the relative risks (RR) being 1.5 (95% CI: 1.0-2.4) [2,6] and 1.8 (95% CI: 1.0-3.3) [7], respectively.…”

Sequence analysis of the E-cadherin (CDH1) gene in a cohort of gastric cancers seen in the western cape

“…Numerous studies have reported the correlation between diet and gastric cancer (Ngoan et al, 2002;Kelley and Duggan, 2003;De Stafani et al, 2004;Nan et al, 2005). It was shown that pickled, salted and fatty foods significantly enhanced the risk of cancer development.…”

“…Another study with 240 subjects also discovered that a high consumption of starchy foods such as rice; white bread; potatoes and tubers played a significant role in the development of this cancer. Further, it was also concluded that diets high in vegetables and fruits reduced the risk of developing stomach cancer (De Stafani et al, 2004).…”