Coffee, black tea and risk of gastric cancer

Gallus, Silvano; Tramacere, Irene; Tavani, Alessandra; Bosetti, Cristina; Bertuccio, Paola; Negri, Eva; Vecchia, Carlo La

doi:10.1007/s10552-009-9350-y

Cited by 12 publications

(8 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The observed gradient across SES factors significantly reflects the importance of lifestyle factors in cancer prevalence. Policies should aim to curb universal risk factors causing cancerous tumors such as tobacco and alcohol, poor diet (insufficient fruit or vegetable intake), overweight and obesity, physical inactivity, chronic infections from Hepatitis B and C virus and environmental risks including ionizing and non-ionizing radiation [5, 8,66–68]. These issues are critical because India has high prevalence of such risk factors.…”

Section: Discussionmentioning

confidence: 99%

Economic burden of cancer in India: Evidence from cross-sectional nationally representative household survey, 2014

2018

View full text Add to dashboard Cite

With the ongoing demographic and epidemiological transition, cancer is emerging as a major public health concern in India. This paper uses nationally representative household survey to examine the overall prevalence and economic burden of cancer in India. The age-standardized prevalence of cancer is estimated to be 97 per 100,000 persons with greater prevalence in urban areas. The evidence suggests that cancer prevalence is highest among the elderly and also among females in the reproductive age groups. Cancer displays a significant socioeconomic gradient even after adjusting for age-sex specifics and clustering in a multilevel regression framework. We find that out of pocket expenditure on cancer treatment is among the highest for any ailment. The average out of pocket spending on inpatient care in private facilities is about three-times that of public facilities. Furthermore, treatment for about 40 percent of cancer hospitalization cases is financed mainly through borrowings, sale of assets and contributions from friends and relatives. Also, over 60 percent of the households who seek care from the private sector incur out of pocket expenditure in excess of 20 percent of their annual per capita household expenditure. Given the catastrophic implications, this study calls for a disease-based approach towards financing such high-cost ailment. It is suggested that universal cancer care insurance should be envisaged and combined with existing accident and life insurance policies for the poorer sections in India. In concluding, we call for policies to improve cancer survivorship through effective prevention and early detection. In particular, greater public health investments in infrastructure, human resources and quality of care deserve priority attention.

show abstract

Section: Discussionmentioning

confidence: 99%

Economic burden of cancer in India: Evidence from cross-sectional nationally representative household survey, 2014

2018

View full text Add to dashboard Cite

show abstract

“…However, the only case-control study that investigated the association of decaffeinated coffee consumption with gastric cancer risk, reported no association. 24 Stratification by anatomical site suggested a positive association between gastric cardia cancer risk and consumption of total and caffeinated coffee. To our knowledge, only two studies have examined the relationship between coffee consumption and gastric cardia cancer risk.…”

Section: Discussionmentioning

confidence: 99%

“…[20][21][22][23] Epidemiological studies that examined the association between either coffee or tea consumption and gastric cancer risk have shown inconclusive results. Although some case-control and cohort studies indicated no association between coffee consumption and risk of gastric cancer, [24][25][26] others have shown an inverse association or a positive association. [27][28][29] A meta-analysis (2006) of 23 studies reported no significant association between coffee consumption and gastric cancer risk.…”

mentioning

confidence: 98%

Total, caffeinated and decaffeinated coffee and tea intake and gastric cancer risk: Results from the EPIC cohort study

Sanikini

Dik

Siersema

et al. 2014

Intl Journal of Cancer

View full text Add to dashboard Cite

Prospective studies examining the association between coffee and tea consumption and gastric cancer risk have shown inconsistent results. We investigated the association between coffee (total, caffeinated and decaffeinated) and tea consumption and the risk of gastric cancer by anatomical site and histological type in the European Prospective Investigation into Cancer and Nutrition study. Coffee and tea consumption were assessed by dietary questionnaires at baseline. Adjusted hazard ratios (HRs) were calculated using Cox regression models. During 11.6 years of follow up, 683 gastric adenocarcinoma cases were identified among 477,312 participants. We found no significant association between overall gastric cancer risk and consumption of total coffee (HR 1.09, 95%‐confidence intervals [CI]: 0.84–1.43; quartile 4 vs. non/quartile 1), caffeinated coffee (HR 1.14, 95%‐CI: 0.82–1.59; quartile 4 vs. non/quartile 1), decaffeinated coffee (HR 1.07, 95%‐CI: 0.75–1.53; tertile 3 vs. non/tertile 1) and tea (HR 0.81, 95%‐CI: 0.59–1.09; quartile 4 vs. non/quartile 1). When stratified by anatomical site, we observed a significant positive association between gastric cardia cancer risk and total coffee consumption per increment of 100 mL/day (HR 1.06, 95%‐CI: 1.03–1.11). Similarly, a significant positive association was observed between gastric cardia cancer risk and caffeinated coffee consumption (HR 1.98, 95%‐CI: 1.16–3.36, p‐trend=0.06; quartile 3 vs. non/quartile 1) and per increment of 100 mL/day (HR 1.09, 95%‐CI: 1.04–1.14). In conclusion, consumption of total, caffeinated and decaffeinated coffee and tea is not associated with overall gastric cancer risk. However, total and caffeinated coffee consumption may be associated with an increased risk of gastric cardia cancer. Further prospective studies are needed to rule out chance or confounding.

show abstract

“…Entretanto, pesquisas revelam que a ingestão de cafeína em excesso pode causar vários distúrbios no organismo como dores de cabeça, irritabilidade, insônia, doenças coronarianas e até evoluir para alguns tipos de câncer (GALLUS et al, 2009;MONTELLA et al, 2009;SIN et al, 2009;TANG et al, 2009). Devido a esses estudos, a procura pelo café descafeinado tem aumentado consideravelmente, sendo até mesmo recomendado por médicos.…”

Section: Introductionunclassified

Avaliação do teor de cafeína em folhas e grãos de acessos de café arábica

Teixeira¹,

Prado²,

Dias³

et al. 2012

Rev. Ciênc. Agron.

View full text Add to dashboard Cite

Resumo -O presente trabalho teve como objetivo identificar, dentro do banco de germoplasma do estado de Minas Gerais, acessos de Coffea arabica L. com baixos teores de cafeína e verificar a existência de correlação entre o teor de cafeína dos grãos e de folhas ainda no estádio de mudas, viabilizando a prática da seleção precoce. Foram utilizados 75 acessos de café (cultivares, híbridos e alguns genótipos selvagens) oriundos do banco de germoplasma de café do Estado de Minas Gerais. Para estudo da correlação foram utilizados oito cultivares no delineamento de blocos casualizados com três repetições. Avaliaram-se os teores de cafeína presentes nos grãos e no terceiro e quarto par de folhas verdadeiras. Seis acessos apresentaram teores de cafeína nos grãos menores que 0,88%. Correlações significativas para teor de cafeína foram observadas entre o terceiro (0,69) e quarto par de folhas (0,92) e os grãos. Foram identificados acessos com teores reduzidos de cafeína e boa produtividade de grãos, podendo ser utilizados como genitores em programas de melhoramento. Verificou-se que é possível realizar a seleção precoce para teor de cafeína, em plantas de cafeeiro ainda no estádio de mudas, por meio da avaliação do quarto par de folhas. Palavras-chave -Coffea arabica L. Melhoramento genético. Correlação fenotípica. Seleção precoce.Abstract -The aim of this study was to identify, within the germplasm bank of the Minas Gerais state, Coffea arabica L. accessions with low levels of caffeine and check the correlation between grain and leaves in seedling stage, making possible the practice of early selection. Seventy-five coffe accessions (cultivars, hybrids and several wild genotypes) were evaluated from the coffee germplasm bank of the Minas Gerais state. In the correlation study, eight cultivars were used on randomized complete block design with three replications. Were evaluated the caffeine levels in the grains and the third and fourth pair of true leaves. Six accessions had caffeine levels in grains smaller than 0.88%. Was also detected a significant correlation between the caffeine levels in the third (0.69) and fourth (0.92) pair of leaves and grains. Genotypes were identified with low levels of caffeine and great yield may be used as parental in breeding programs. It is possible to perform early selection for caffeine content in coffee plants, still in the seedling stage, by evaluating the fourth pair of leaves.

show abstract

Coffee, black tea and risk of gastric cancer

Abstract: Our investigation, based on a uniquely large dataset, provides convincing evidence that coffee and black tea consumption is unlikely to be strongly associated with gastric cancer risk.

Cited by 12 publications

References 34 publications

Economic burden of cancer in India: Evidence from cross-sectional nationally representative household survey, 2014

Economic burden of cancer in India: Evidence from cross-sectional nationally representative household survey, 2014

Total, caffeinated and decaffeinated coffee and tea intake and gastric cancer risk: Results from the EPIC cohort study

Avaliação do teor de cafeína em folhas e grãos de acessos de café arábica

Contact Info

Product

Resources

About