Dietary nucleotide administration influences growth, immune responses and oxidative stress resistance of juvenile red sea bream (Pagrus major)

Efficacy of nucleotide related products on growth, blood chemistry, oxidative stress and growth factor gene expression of juvenile red sea bream, Pagrus major

“…explanation how dietary nucleotide and nucleosides work to enhance growth. However, it is assumed that the growth-enhancing effect of inosine and other nucleotide in the present study resulted from improved feed intake at the beginning of weaning, promoting more rapid food intake that reduced nutrient leaching into the water or possibly playing roles in metabolism (Metailler et al, 1983, Hossain et al, 2016. It is also well known that growth response was strongly related to improve feed utilization.…”

“…Hematological parameters are being used as an effective and sensitive index for the physiological and pathological condition as well as welfare of fish (Hossain et al, 2016). Blood parameters obtained in the present experiment are considered to be within the normal range for juvenile red sea beam, compared to those of the previous findings (Aoki et al, 1998;Hossain et al 2016).…”

“…In aquaculture dietary nucleotide and its related products supplementation has been shown to enhance growth of certain fish species (reviewed by Li and Gatlin, 2006) immune responses and disease resistance of all male hybrid tilapia (Saratheradon niloticus ♀ × Saratheradon aureus ♂ (Ramadan et al, 1994), Atlantic salmon (Salmo salar L.) (Burrells et al, 2001a), common carp (Cyprinus carpio L.) (Sakai et al, 2001), hybrid striped bass (Morone chrysops × Morone saxatilis) (Li et al, 2004), grouper (Epinephelus malabaricus) (Lin et al, 2009), red drums (Sciaenops ocellatus) (Cheng et al, 2011), rainbow trout (Oncorhynchus mykiss) (Tahmasebi-Kohyani et al, 2012) and Japanese flounder (Paralichthys olivaceus) (Song et al, 2012). Supplementation of nucleotides was also reported to increase stress tolerance in Atlantic salmon (Burrells et al, 2001b), rainbow trout (Leonardi et al, 2003), red sea bream (Hossain et al, 2016) and even gastrointestinal physiology and morphology of tilapia (Ramadan et al, 1994), Atlantic salmon (Burrells et al, 2001b) and red drum (Cheng et al, 2011).…”

“…Exposure to stress places additional demands on available nucleotides, and an additional exogenous supply of nucleotides provided by dietary supplementation may help to counter the immunosuppressive effects of stress (Low et al, 2003). Although, there are some research into potential growth and health benefits of dietary nucleotides in aquaculture species (Burrells et al, 2001a(Burrells et al, , 2001bLi et al, 2004;Cheng et al, 2011;Song et al, 2012, Hossain et al, 2016. However, in most of cases, purified nucleotide mixtures were used and still, some gap exists about current knowledge of nucleotide supplementation in fish diets and its effects on physiology and immunity.…”

Catalase, superoxide dismutase, glutathione peroxidase and oxygen radical absorbance capacity in the gut of juvenile pacu Piaractus mesopotamicus and dourado Salminus brasiliensis fed bovine first milk secretion

“…The authors report that nucleotides and nucleosides regulate bodily functions and participate in fatty acid biosynthesis. Hossain et al (2016) reported that nucleotide administration influences growth, immune responses and oxidative stress resistance of juvenile red sea bream Pagrus major. Changes of the intestinal mucosa function results in increased uptake of luminal toxic materials such as antigens, toxins, and pro-inflammatory molecules (Söderholm & Perdue, 2001).…”