Dietary mannan-oligosaccharides supplementation could affect performance, immunocompetence, serum lipid metabolites, intestinal bacterial populations, and ileal nutrient digestibility in aged laying hens

Combined supplementation of organic acid blend and mannanoligosaccharide suppresses expression of heat shock protein 70 in broilers

“…Microflora of GIT is the first barrier that prevents the host from negative effects of pathogens by inhibiting their colonization (Brzoska et al., 2007). Pathogens that are having mannose-specific type-1 fimbriae attach to MOS rather than attaching to enterocytes and move out of the intestine without colonization (Ghasemian and Jahanian, 2016). The beneficial effects of LAB include colony formation on mucous membrane of GIT, thus preventing them from pathogens (Brzoska et al, 2007).…”

“…Adhesion of pathogenic bacteria to enterocytes upsurges their growth by preventing attachment of antibodies (Liu et al, 2008), MOS blocks the colonization of gram negative bacteria via establishing an alternative binding site thus compelling them to move through the intestine (Pinheiro et al, 2009). Pathogens that are having mannose-specific type-1 fimbriae attach to MOS rather than attaching to enterocytes and move out of the intestine without colonization (Ghasemian and Jahanian, 2016).…”

“…It has been referred as an alternative to antibiotics in broiler feed (Ghasemian and Jahanian, 2016) and is having the ability to alter changes in intestinal microarchitecture by decreasing bacterial challenge thus promoting better absorption of nutrients and ultimately increasing production (Rokade et al, 2016). Adhesion of pathogenic bacteria to enterocytes upsurges their growth by preventing attachment of antibodies (Liu et al, 2008), MOS blocks the colonization of gram negative bacteria via establishing an alternative binding site thus compelling them to move through the intestine (Pinheiro et al, 2009).…”

Alternatives to the Use of Antibiotics in Egg Production

“…Among them, there are several options, such as MOS -extracted from the cell wall of Saccharomyces cerevisiae, FOSsynthesized from Aspergillus niger or Aureobasidium pullulans, and others such as Glycoligosaccharides, Galactoligosaccharides. In the analysis of the doses of MOS in 0.5, 1, 1.5 and 2g/kg in the diets [9], a greater digestibility of the crude protein verified in all the doses tested in relation to the control without use of the MOS. This effect was potentiated and improved in relation to the lower availability of nutrients to the harmful bacteria, so that their populations was reduced, especially with 1g / kg in Escherichia coli and with 1.5 g / kg in Salmonella spp.…”

Transcriptome Analysis Reveals Mechanism Underlying the Differential Intestinal Functionality of Laying Hens in the Late Phase and Peak Phase of Production

“…quality as compared with those at peak production, resulting in a restricted economic benefit of layer production [1,2]. One crucial reason for the compromises of production performance and egg quality of laying hens in the late phase of production could be the corresponding alteration of intestinal functional state [3,4], whose importance has been increasingly recognized in poultry production due to its contribution to the overall health and production performance of poultry [5]. Since there was a deterioration of intestinal functions such as absorption and barrier dysfunction, immune and defense defects with aging [6,7], the laying hens in the late and peak phase of production were speculated to display distinct differences in terms of intestinal functionality.…”