Dietary magnesium intake and risk of depression

Sun, Chunge; Wang, Rui; Li, Zongyao; Zhang, Dongfeng

doi:10.1016/j.jad.2018.12.114

Cited by 62 publications

(43 citation statements)

References 42 publications

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“…These findings in our study are supported by studies in older people where significant associations were found between low levels of folate and B12 in serum and increased risk of depression in both sexes [48], and a high dietary intake of B6 and B12 showed significant protective effect for the development of depression [49]. Furthermore, a low intake of magnesium in the diet has also been associated with increased risk of depression in populations of younger and older persons in other studies [50,51]. Previous studies and a meta-analysis [52,53] found significant correlations with folic acid levels and depression, where low blood levels were associated with increased risk and a high diet-based intake of folic acid with a protective effect against depression.…”

Section: Discussionsupporting

confidence: 89%

Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression

Ljungberg

Bondza

Lethin

2020

IJERPH

100

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Background: Mental illness is one of the fastest rising threats to public health, of which depression and anxiety disorders are increasing the most. Research shows that diet is associated with depressive symptoms or depression (depression). Aim: This study aimed to investigate the diets impact on depression, by reviewing the scientific evidence for prevention and treatment interventions. Method: A systematic review was conducted, and narrative synthesis analysis was performed. Result: Twenty scientific articles were included in this review. The result showed that high adherence to dietary recommendations; avoiding processed foods; intake of anti-inflammatory diet; magnesium and folic acid; various fatty acids; and fish consumption had a depression. Public health professionals that work to support and motivate healthy eating habits may help prevent and treat depression based on the evidence presented in the results of this study. Further research is needed to strengthen a causal relationship and define evidence-based strategies to implement in prevention and treatment by public healthcare.

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Section: Discussionsupporting

confidence: 89%

Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression

Ljungberg

Bondza

Lethin

2020

IJERPH

100

View full text Add to dashboard Cite

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“…The following covariates were included in this study: age, gender, race, marital status, education level, annual household income, smoking status, alcohol consumption status, work activity, recreational activity, body mass index (BMI), hypertension, diabetes, coronary heart disease, and energy intake. The classifications of covariates were based on our previous studies [13,14,37] and are shown in Table S1.…”

Section: Covariatesmentioning

confidence: 99%

“…Epidemiologic studies have shown that depression is related to genetic and environmental factors, especially dietary factors [6][7][8][9]. For instance, vegetables [10], fruits [10], fish [11], and dietary fiber [12] have been reported to reduce the risk of depression, and some nutrients [13,14] (e.g., magnesium, zinc, iron, copper, and selenium) can also reduce the risk of depression.…”

Section: Introductionmentioning

confidence: 99%

Associations of n-3, n-6 Fatty Acids Intakes and n-6:n-3 Ratio with the Risk of Depressive Symptoms: NHANES 2009–2016

Zhang

Sun

et al. 2020

Nutrients

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Many studies have explored the association between n-3 fatty acids and depression, but research on the associations of n-6 fatty acids and n-6:n-3 ratio with depression is more scarce, and the results are controversial. Therefore, we conducted this cross-sectional study to explore the associations of n-3 and n-6 fatty acid intakes and n-6:n-3 ratio with the risk of depressive symptoms using data from National Health and Nutrition Examination Survey (NHANES) 2009–2016. Dietary data on n-3 and n-6 fatty acids were obtained through two 24-h dietary recall interviews, and were adjusted by energy. Depressive symptoms were measured by PHQ-9 (nine-item Patient Health Questionnaire). We applied logistic regression and restricted cubic spline models to assess the relationships of n-3 and n-6 fatty acids intake and n-6:n-3 ratio with the risk of depressive symptoms. A total of 17,431 individuals over 18 years old were enrolled in this study. In the multivariate-adjusted model 2, compared with the lowest category, the highest odd ratios (ORs) with 95% confidence intervals (CIs) for n-3 fatty acid intake and n-6:n-3 ratio were 0.71 (0.55–0.92) and 1.66 (1.10–2.50), and middle OR (95% CI) for n-6 fatty acid intake was 0.72 (0.56–0.92), respectively. Our study suggests that n-3 and n-6 fatty acids intake were inversely associated with the risk of depressive symptoms, while the n-6:n-3 ratio was positively associated with the risk of depressive symptoms.

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“…There have been plenty of studies conducted to investigate the risk factors of depression; however, the aetiology is still unclear. Physical activity (8,9) and dietary factors including healthy diet (10) , fibre intake (11,12) , vitamins (vitamin D (13,14) , vitamin B 12 and folate (14,15) ) and some minerals (Mg, Zn, Fe and Cu (16)(17)(18)(19)(20)(21)(22) ) were found to have negative associations with depression. Regarding dietary protein, several epidemiological studies have explored its association with depression.…”

mentioning

confidence: 99%

Association between dietary protein intake and the risk of depressive symptoms in adults

Zhang

et al. 2020

Br J Nutr

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AbstractDepression is an important public health problem. The aim of the study is to explore the associations of total protein intake and protein sources with the risk of depressive symptoms. This cross-sectional study used data from the National Health and Nutrition Examination Survey for the years 2007–2014. Dietary protein intake was obtained from two 24-h dietary recall interviews. Depressive symptoms were assessed by a nine-item Patient Health Questionnaire. Logistic regression models and restricted cubic spline models were used to estimate the associations of total protein intake (g/kg per d) and protein sources with the risk of depressive symptoms. A total of 17 845 individuals aged 18 years and older were included in this study. Total protein intake was inversely associated with the risk of depressive symptoms. The full-adjusted OR of depressive symptoms was 0·34 (95 % CI 0·17, 0·68) for quartile (Q) 4 v. Q1 of total protein intake. For protein intake from milk and milk products, the association with depressive symptoms was significant both for Q2 v. Q1 (OR 0·61; 95 % CI 0·41, 0·93) and Q3 v. Q1 (OR 0·37; 95 % CI 0·24, 0·59) in the full-adjusted model. In the dose–response analysis, the shape of the associations of total protein intake and protein intake from milk and milk products with the risk of depressive symptoms was approximately L-shaped and U-shaped, respectively. The present study demonstrated that total protein intake and protein intake from milk and milk products might reduce the risk of depressive symptoms in US adults.

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Dietary magnesium intake and risk of depression

Cited by 62 publications

References 42 publications

Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression

Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression

Associations of n-3, n-6 Fatty Acids Intakes and n-6:n-3 Ratio with the Risk of Depressive Symptoms: NHANES 2009–2016

Association between dietary protein intake and the risk of depressive symptoms in adults

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