Dietary magnesium increases calcium absorption of ovine small intestine in vivo and in
vitro

Kozakai, Takaharu; Uozumi, Norio; Katoh, K.; Obara, Yoshiaki

doi:10.1051/rnd:2002003

Cited by 9 publications

(6 citation statements)

References 32 publications

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“…But the increased relation of Ca 2+ to total Ca found with low DCAD in ruminal fluid (Table ) accompanied by unchanged transmural potential difference might have facilitated absorption of Ca in vivo and hence stabilised plasma concentrations. Furthermore, greater ruminal concentrations of Mg and Cl, as shown for sheep on the low DCAD diet in the current study, were associated with increased gastrointestinal Ca absorption in vivo and in vitro (Kozakai et al., ).…”

Section: Discussionsupporting

confidence: 69%

Stimulating effects of a diet negative in dietary cation–anion difference on calcium absorption from the rumen in sheep

Wilkens

Praechter

Breves

et al. 2015

Animal Physiology Nutrition

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The concept of feeding anionic salts in late gestation is widely used to prevent milk fever in dairy cows. While the effects of these diets on renal Ca excretion and tissue responsiveness towards parathyroid hormone have clearly been demonstrated, data on a potential impact on gastrointestinal Ca absorption are conflicting. Therefore, the aim of this study was to investigate the influence of feeding a diet negative in dietary cation-anion difference (DCAD) on ruminal mineral concentrations, fermentation products, electrophysiological properties of rumen epithelia and Ca flux rates. For this purpose, sheep were kept for 3 weeks on diets that were either positive or negative in DCAD. The induction of a compensated hyperchloremic metabolic acidosis could be demonstrated by increased plasma Cl and enhanced concentrations of ionised Ca, while plasma concentrations of HCO3- and base excess were decreased with the low DCAD diet. Neither transmural potential differences nor fermentation products were affected, but ruminal concentrations of Cl and Mg as well as the relation of ionised to total Ca were increased. Ussing chamber experiments revealed alterations of electrophysiological parameters and an increase in the electroneutral component of Ca flux rates from the mucosal to the serosal side of rumen epithelium. As plasma calcitriol concentrations were not affected, it can be concluded that the administration of anionic salts results in a vitamin D-independent stimulation of ruminal Ca transport.

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Section: Discussionsupporting

confidence: 69%

Stimulating effects of a diet negative in dietary cation–anion difference on calcium absorption from the rumen in sheep

Wilkens

Praechter

Breves

et al. 2015

Animal Physiology Nutrition

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show abstract

“…Fine et al ( 150 ) have found that increasing dietary Mg 2+ had no effect on Ca absorption. Kosakai et al ( 151 ) have demonstrated in sheep that the apparent Ca absorption tended to increase when the dietary Mg 2+ content was increased, which was accompanied without an alteration in the plasma Ca concentration and increased urinary Ca excretion. Bae et al ( 152 ) have shown that the consumption of seaweed Ca extract or inorganic calcium carbonate with Mg 2+ oxide in OVX rats produced a similar intestinal Ca absorption, but only the seaweed Ca extract caused an increase in femoral BMD and strength in OVX rats.…”

Section: Nutritional Factors Affecting Intestinal Calcium Absorptionmentioning

confidence: 99%

Dietary and pharmacological compounds altering intestinal calcium absorption in humans and animals

et al. 2015

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The intestine is the only gate for the entry of Ca to the body in humans and mammals. The entrance of Ca occurs via paracellular and intracellular pathways. All steps of the latter pathway are regulated by calcitriol and by other hormones. Dietary and pharmacological compounds also modulate the intestinal Ca absorption process. Among them, dietary Ca and P are known to alter the lipid and protein composition of the brush-border and basolateral membranes and, consequently, Ca transport. Ca intakes are below the requirements recommended by health professionals in most countries, triggering important health problems. Chronic low Ca intake has been related to illness conditions such as osteoporosis, hypertension, renal lithiasis and incidences of human cancer. Carbohydrates, mainly lactose, and prebiotics have been described as positive modulators of intestinal Ca absorption. Apparently, high meat proteins increase intestinal Ca absorption while the effect of dietary lipids remains unclear. Pharmacological compounds such as menadione, dl-butionine-S,R-sulfoximine and ursodeoxycholic acid also modify intestinal Ca absorption as a consequence of altering the redox state of the epithelial cells. The paracellular pathway of intestinal Ca absorption is poorly known and is under present study in some laboratories. Another field that needs to be explored more intensively is the influence of the gene × diet interaction on intestinal Ca absorption. Health professionals should be aware of this knowledge in order to develop nutritional or medical strategies to stimulate the efficiency of intestinal Ca absorption and to prevent diseases.

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“…In this study, it was decided to apply the eggshell in gingerbread since it is a popular snack and willingly eaten by children and the elderly, hence becoming a source of essential calcium for healthy bone growth. Moreover, the presence of vitamin D, inulin, as well as other indigestible oligosaccharides, magnesium, or short-chain fatty acids, is beneficial for calcium absorption in the body [ 18 , 39 , 40 ]. The novelty of this article was the combined application of calcium from eggshell powder and antioxidant from green tea in gingerbread as a new alternative to increase calcium intake and reduce the risk of osteoporosis.…”

Section: Introductionmentioning

confidence: 99%

Innovative Application of Chicken Eggshell Calcium to Improve the Functional Value of Gingerbread

Arnold

Rajagukguk

Sidor

et al. 2022

IJERPH

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Food waste, such as eggshell, can be an environmental problem if it is not properly managed. One of the ways to solve this is by using the eggshell as the cheap calcium source in food products. Polish gingerbread fortified with chicken eggshell powder (ESP) calcium was developed to solve the eggshell waste problem and to reduce the risk of osteoporosis. This study focused on the effect of ESP addition on basic composition, sensory evaluation, and antioxidative activity of gingerbread. Two samples of gingerbread without and with 3% (w/w of wheat flour) ESP, with controlled green tea powder (4% w/w of white chocolate) were analyzed. Results of the research showed that the addition of 3% ESP significantly increased the ash and calcium content (p < 0.05) without changing the appearance, aroma, texture, taste profiles, and the hedonic score of gingerbread. The gingerbread samples were then stored for 2 months and were analyzed every month. The hedonic evaluation of the aroma of both gingerbread samples decreased significantly (p < 0.05) during storage. During 2 months of storage, the antioxidative activity of gingerbread fortified with 3% ESP was not significantly different compared to the control (p > 0.05), particularly in ABTS and ORACFL assay. The ABTS, DPPH, and ORACFL assays showed decreasing antioxidative activity during storage, which was also in accordance with decreasing total phenolic content of both gingerbread samples. In PCL assay, the lipid-soluble antioxidant activity in gingerbread with 3% ESP was significantly higher during 2 months of storage, compared to the control (p < 0.05). The developed product might be a potential alternative to improve the calcium (26% daily value (DV) recommendation per 100 g) and antioxidant intake in order to prevent calcium deficiency. Gingerbread enriched with an organic source of calcium may become an innovative product to reduce the risk of developing osteoporosis in the elderly population, having potential health and economic significance, given the incidence of osteoporosis and the costs of treating this disease.

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Dietary magnesium increases calcium absorption of ovine small intestine in vivo and in vitro

Cited by 9 publications

References 32 publications

Stimulating effects of a diet negative in dietary cation–anion difference on calcium absorption from the rumen in sheep

Stimulating effects of a diet negative in dietary cation–anion difference on calcium absorption from the rumen in sheep

Dietary and pharmacological compounds altering intestinal calcium absorption in humans and animals

Innovative Application of Chicken Eggshell Calcium to Improve the Functional Value of Gingerbread

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