Dietary isoflavones in the prevention of cardiovascular disease – A molecular perspective

Plant-Derived Agents with Anti-Glycation Activity

“…Soy products and soybeans are particularly abundant sources of isoflavones which have both antioxidant and phytoesterogenic activities that may contribute to their potential anticarcinogenic and cardioprotective effects [94][95][96]. High soybean consumption has been implicated in the longevity of the Japanese [97].…”

Plant Polyphenols as Antioxidants Influencing the Human Health

“…Glycine max Genista tinctoria (Beck et al, 2005;Peng et al, 2004) (Rimbach et al, 2008;Rigano et al, 2009) Table 1. Classification of some common flavonoids indicating their major plant sources.…”

Phytochemicals in Soy and Their Health Effects

“…A number of cardioprotective benefits have been attributed to dietary isoflavones including reduction in LDL cholesterol, inhibition of pro-inflammatory cytokines, cell adhesion www.intechopen.com proteins and inducible nitric oxide production, potential reduction in the susceptibility of the LDL particle to oxidation, inhibition of platelet aggregation and an improvement in vascular reactivity (50).There are not randomized trials investigating the action of isoflavones on the incidence of clinical events. A few recent, well-designed studies have suggested an association of the ingestion of isoflavones with a reduction in the atherosclerotic burden, as indicated by the measurement of the intima-media thickness in carotid vessels (51).…”

“…The scavenging superoxide activity of DDMP soyasaponins is caused by the DDMP moiety attached to the triterpene aglycon since soyasaponin I (35), which is derived from soyasaponin βg (50). Lack of this group didn't show the scavenging activity (109).…”