Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women

Parra‐Cabrera, Socorro; Stein, Aryeh D.; Wang, Meng; Martorell, Reynaldo; Rivera, Juan Á.; Ramakrishnan, Usha

doi:10.1111/j.1740-8709.2010.00254.x

Cited by 41 publications

(41 citation statements)

References 25 publications

(40 reference statements)

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“…We assessed maternal dietary intake at 18-22 wk gestation using a 110-item FFQ that included specific questions about consumption of sources of DHA such as freshwater fish, seafood, canned tuna and sardines, salmon, trout, and cod liver oil in the previous 3 mo (24,25). Estimates of (n-3) PUFA intake ascertained using this FFQ correlated reasonably well with erythrocyte membrane (n-3) PUFA phospholipid concentration (26).…”

Section: Methodsmentioning

confidence: 98%

Docosahexaenoic Acid Supplementation from Mid-Pregnancy to Parturition Influenced Breast Milk Fatty Acid Concentrations at 1 Month Postpartum in Mexican Women

Imhoff‐Kunsch

Stein

Villalpando

et al. 2011

The Journal of Nutrition

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(n-3) PUFA, including DHA, are essential for neural development and accumulate extensively in the fetal and infant brain. (n-3) PUFA concentrations in breast milk, which are largely dependent on maternal diet and tissue stores, are correlated with infant PUFA status. We investigated the effect of prenatal DHA supplementation on PUFA concentrations in breast milk at 1 mo postpartum. In a double-blind, randomized, controlled trial conducted in Mexico, pregnant women were supplemented daily with 400 mg DHA or placebo from 18-22 wk gestation to parturition. Fatty acid concentrations in breast milk obtained from 174 women at 1 mo postpartum were determined using GLC and were expressed as % by weight of total detected fatty acids. Breast milk DHA concentrations in the DHA and placebo groups were (mean ± SD) 0.20 ± 0.06 and 0.17 ± 0.07 (P < 0.01), respectively, and those of α-linolenic acid (ALA) were 1.38 ± 0.47 and 1.24 ± 0.46 (P = 0.01), respectively. Concentrations of EPA and arachidonic acid did not differ between groups (P > 0.05). Maternal plasma DHA concentrations at 1 mo postpartum correlated positively with breast milk DHA at 1 mo postpartum in both the placebo and DHA groups (r = 0.4; P < 0.01 for both treatment groups). Prenatal DHA supplementation from 18-22 wk gestation to parturition increased concentrations of DHA and ALA in breast milk at 1 mo postpartum, providing a mechanism through which breast-fed infants could benefit.

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Section: Methodsmentioning

confidence: 98%

Docosahexaenoic Acid Supplementation from Mid-Pregnancy to Parturition Influenced Breast Milk Fatty Acid Concentrations at 1 Month Postpartum in Mexican Women

Imhoff‐Kunsch

Stein

Villalpando

et al. 2011

The Journal of Nutrition

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“…An inverse association between socioeconomic level and intake of alpha-linolenic acid was also detected in pregnant Mexican women with diets comprising a lipid profile close to that of the pregnant women from Botucatu. In Mexico, as in Brazil, access to food sources of omega-3 fatty acids appears linked to economic constraints [20], a factor to be considered when selecting foods to encourage intake of omega-3 fatty acids.…”

Section: Discussionmentioning

confidence: 99%

Insufficient intake of alpha-linolenic fatty acid (18:3n-3) during pregnancy and associated factors

et al. 2017

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A B S T R A C T ObjectiveTo analyze alpha-linolenic fatty acid intake in two cohorts of pregnant women, and to identify factors associated with alpha-linolenic acid intake. MethodsThis is a cohort study involving pregnant women with low obstetric risk (N=353) in public health system from a municipality of São Paulo state, Brazil. In each trimester, two 24-hour food recalls were collected. Descriptive analyses of dietary lipid profiles were performed, followed by a multiple comparison test. According to the trimester of pregnancy, differences were assessed using the mean difference test. To evaluate the adequacy of

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“…DHA intakes in our study population were low (median: 80 mg/day) compared with the recommended intake of at least 200 mg/ day. 26,40 Intake of n-3 PUFA in the United States is an estimated 1.6 g/day, and intake of DHA is ϳ100 to 200 mg/day. 41 Our study population experienced lower infectious disease rates than are reported from many developing countries, in particular for diarrhea and fever.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Docosahexaenoic Acid Supplementation and Infant Morbidity: Randomized Controlled Trial

2011

PEDIATRICS

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WHAT'S KNOWN ON THIS SUBJECT:Intake of long-chain polyunsaturated fatty acids influences immune cell function; however, the influence on infant morbidity of maternal docosahexaenoic acid (DHA) intake during pregnancy is unknown. In 1 study, allergic responses and immunologic profiles in infants were affected by DHA supplementation during pregnancy in atopic pregnant women. WHAT THIS STUDY ADDS:Maternal DHA supplementation (400 mg/day) during pregnancy decreased the occurrence of colds in infants at 1 month and influenced illness symptom duration at 1, 3, and 6 months. This dose of DHA can be achieved through diet. abstract OBJECTIVE: Long-chain polyunsaturated fatty acids such as docosahexaenoic acid (DHA) influence immune function and inflammation; however, the influence of maternal DHA supplementation on infant morbidity is unknown. We investigated the effects of prenatal DHA supplementation on infant morbidity. METHODS:In a double-blind randomized controlled trial conducted in Mexico, pregnant women received daily supplementation with 400 mg of DHA or placebo from 18 to 22 weeks' gestation through parturition. In infants aged 1, 3, and 6 months, caregivers reported the occurrence of common illness symptoms in the preceding 15 days. RESULTS:Data were available at 1, 3, and 6 months for 849, 834, and 834 infants, respectively. The occurrence of specific illness symptoms did not differ between groups; however, the occurrence of a combined measure of cold symptoms was lower in the DHA group at 1 month (OR: 0.76; 95% CI: 0.58 -1.00). At 1 month, the DHA group experienced 26%, 15%, and 30% shorter duration of cough, phlegm, and wheezing, respectively, but 22% longer duration of rash (all P Յ .01). At 3 months, infants in the DHA group spent 14% less time ill (P Ͻ .0001). At 6 months, infants in the DHA group experienced 20%, 13%, 54%, 23%, and 25% shorter duration of fever, nasal secretion, difficulty breathing, rash, and "other illness," respectively, but 74% longer duration of vomiting (all P Ͻ .05).CONCLUSIONS: DHA supplementation during pregnancy decreased the occurrence of colds in children at 1 month and influenced illness symptom duration at 1, 3, and 6 months. Dr Imhoff-Kunsch contributed to the design of the morbidityspecific aspects of the study, conducted the statistical analysis, and wrote the manuscript. Dr Stein contributed to the study design, reviewed the accuracy of the statistical methods and interpretation of results, and reviewed the initial article and subsequent revisions. Dr

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Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women

Cited by 41 publications

References 25 publications

Docosahexaenoic Acid Supplementation from Mid-Pregnancy to Parturition Influenced Breast Milk Fatty Acid Concentrations at 1 Month Postpartum in Mexican Women

Docosahexaenoic Acid Supplementation from Mid-Pregnancy to Parturition Influenced Breast Milk Fatty Acid Concentrations at 1 Month Postpartum in Mexican Women

Insufficient intake of alpha-linolenic fatty acid (18:3n-3) during pregnancy and associated factors

Prenatal Docosahexaenoic Acid Supplementation and Infant Morbidity: Randomized Controlled Trial

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