Dietary fiber intake and stroke risk: a meta-analysis of prospective cohort studies

Abstract

Findings of this meta-analysis indicate a significant inverse dose-response relationship between dietary fiber intake and risk of stroke.

Letter by Tikhonoff et al Regarding Article, “Dietary Fiber Intake and Risk of First Stroke: A Systematic Review and Meta-analysis”

“…3 This association was present both for soluble and for insoluble fiber, and independent of age, sex, and classic atherogenetic risk factors. This is consistent with a recent metaanalysis by Chen et al 4 on dietary fiber intake and risk of stroke, suggesting no significant difference between sexes.…”

Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies

“…The midpoints of the upper and lower boundaries of each category were used if the median or mean were not reported. For studies that reported the open upper boundaries or uppermost boundaries closed with extreme value, we assumed the width of the interval to be the same as in the closest category 11. A restricted cubic spline model with four knots set at the 5th, 35th, 65th and 95th centile levels of LTPA was then produced using the generalised least square regression and taking into account the correlation between each set of published RRs 12.…”

Dietary Fiber Intake Is Inversely Associated with Stroke Incidence in Healthy Swedish Adults

“…Although results from individual studies on dietary fiber intake in relation to stroke have been inconsistent, 3 meta-analyses have reported an overall significant inverse association (6,19,20). For example, in 2 dose-response meta-analyses, including 6 (19) or 8 (20) studies, the risk of stroke decreased by 7% for every 7 g/d (20) or by 12% for every 10 g/d (19) increment of total fiber intake.…”

“…For example, in 2 dose-response meta-analyses, including 6 (19) or 8 (20) studies, the risk of stroke decreased by 7% for every 7 g/d (20) or by 12% for every 10 g/d (19) increment of total fiber intake. Few previous studies have considered potential confounding from other nutrients present in fiber-rich foods.…”