Dietary arginine requirement for gibel carp (Carassis auratus gibelio var. CAS III) reduces with fish size from 50g to 150g associated with modulation of genes involved in TOR signaling pathway

Tu, Yongqin; Xie, Shouqi; Han, Dong; Yang, Yunxia; Jin, Junyan; Zhu, Xiaoming

doi:10.1016/j.aquaculture.2015.02.031

Cited by 64 publications

(56 citation statements)

References 69 publications

(88 reference statements)

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“…Their presence in central areas regulating food intake is however reasonable considering that most fish are carnivorous, and therefore they are strongly dependent (certainly much more than omnivorous mammals in which most studies have been carried out to date) on dietary protein/amino acid levels for functioning. The only studies available in fish demonstrated in peripheral tissues like muscle and liver the effect of changes in amino acid levels in mRNA abundance of mTOR (Seiliez et al, 2008; Wacyk et al, 2012; Tu et al, 2015; Liang et al, 2016; Xu et al, 2016). …”

Section: Nutrient Sensing Mechanisms In Fishmentioning

confidence: 99%

Nutrient Sensing Systems in Fish: Impact on Food Intake Regulation and Energy Homeostasis

2017

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Evidence obtained in recent years in a few species, especially rainbow trout, supports the presence in fish of nutrient sensing mechanisms. Glucosensing capacity is present in central (hypothalamus and hindbrain) and peripheral [liver, Brockmann bodies (BB, main accumulation of pancreatic endocrine cells in several fish species), and intestine] locations whereas fatty acid sensors seem to be present in hypothalamus, liver and BB. Glucose and fatty acid sensing capacities relate to food intake regulation and metabolism in fish. Hypothalamus is as a signaling integratory center in a way that detection of increased levels of nutrients result in food intake inhibition through changes in the expression of anorexigenic and orexigenic neuropeptides. Moreover, central nutrient sensing modulates functions in the periphery since they elicit changes in hepatic metabolism as well as in hormone secretion to counter-regulate changes in nutrient levels detected in the CNS. At peripheral level, the direct nutrient detection in liver has a crucial role in homeostatic control of glucose and fatty acid whereas in BB and intestine nutrient sensing is probably involved in regulation of hormone secretion from endocrine cells.

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Section: Nutrient Sensing Mechanisms In Fishmentioning

confidence: 99%

Nutrient Sensing Systems in Fish: Impact on Food Intake Regulation and Energy Homeostasis

2017

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“…Improved production of polyamines was observed during inflammatory responses of Atlantic salmon ( Salmo salar ) immune cells ( Andersen, Taylor, Holen, Aksnes, & Espe, ; Holen et al, ). Increased target of rapamycin (mTOR) signalling activity was reported in blunt snout bream ( Megalobrama amblycephala ) and gibel carp ( Carassius auratus gibelio ) (Liang et al, ; Tu et al, ). Furthermore, it improved the survival of channel catfish ( Ictalurus punctatus ) and turbot ( Scophtalmus maximus ) after being challenged with Edwardsiella ictaluri and Edwardsiella tarda respectively (Bentello & Gatlin, 2001; Zhang et al, ).…”

Section: Introductionmentioning

confidence: 99%

Effects of arginine supplementation on growth performance and plasma arginine, ornithine and citrulline dynamics of rainbow trout, Oncorhynchus mykiss

et al. 2019

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This study aimed to re‐evaluate the effect of excessive arginine supplementation on growth and feed efficiency of rainbow trout, and to assess the effect of dietary arginine supplementation on hepatic amino acid composition, expression of arginase Ⅱ (ARG 2), inducible nitric oxide synthase (iNOS), and heat shock protein 70 (HSP70) genes in the intestine, and plasma arginine, ornithine, citrulline and urea levels at 0, 6, 12 and 18 hr‐postprandial. Rainbow trout (body weight: 60.5–65 g) were fed diets containing 1.47 (control [CTRL]), 3.89 (3.89A) and 5.64% (5.64A) arginine for nine weeks. Higher muscle protein content was observed in 3.89A than CTRL (p < 0.05). In postprandial study, plasma arginine of 5.64A kept increased until 12 hr‐postprandial and reached identical value (around 150 µg/ml) until 18 hr‐postprandial in 5.64A. Significant increase of plasma arginine level was only observed in arginine supplemented group. Meanwhile, plasma citrulline level in CTRL was significantly higher than in 5.64A at 18 hr‐postprandial. A significantly higher hepatic citrulline level was also observed in CTRL than in 5.64A (p < 0.05). Significantly higher plasma and hepatic free ornithine level was observed in 5.64A than CTRL while significantly higher expression of intestinal ARG2 and HSP70 was found in arginine supplemented groups. These results suggest that citrulline availability seems to be stimulated by arginine deficiency in the CTRL and the presence of arginase in the intestine to regulate excess dietary arginine.

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“…Many studies have reported the protein and amino acids requirements in gibel carp (Tu et al, 2015;Yang et al, 2006;Ye et al, 2015). CAS III) is a main freshwater culture fish in China.…”

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confidence: 99%

Effects of dietary leucine levels on growth, tissue protein content and relative expression of genes related to protein synthesis in juvenile gibel carp (Carassius auratus gibeliovar. CAS III)

Zou

Cao

et al. 2018

Aquac Res

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An 8-week feeding trial was conducted to investigate the impacts of dietary leucine on growth, hepatopancreas and muscle protein content and relative expressions of protein synthesis-related genes in juvenile gibel carp (5.2 g). Triplicate tanks of fish (22 fish per tank) were fed with a low (0.82%), middle (1.90%) or high (2.99%) leucine diet to apparent satiation three times a day. The results showed that the weight gain (WG) and feed efficiency (FE) of the fish fed with the 1.90% leucine diet had the highest values compared to those of other two groups (p < .05). Dietary leucine significantly affected the protein and lipid contents of the hepatopancreas (p < .05), but not muscle or the whole body composition of the fish. The amino acid contents (Arginine, Leucine, Methionine, Phenylalanine, Alanine, Aspartic acid, Glutamic acid and Proline) of the dorsal muscles of fish fed with a 1.90% leucine diet were significantly higher than those fed with a 0.82% leucine diet. Moreover, transcriptional levels of target genes of rapamycin (TOR), ribosomal protein S6 kinase 1 (S6K1), eukaryotic translation initiation factor 4E (eIF4E) and leucyl-tRNA synthetase (LARS) in the hepatopancreas were significantly up-regulated (p < .05), but eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) was significantly down-regulated (p < .05) with the increasing dietary leucine levels. However, dietary leucine had no effects on the gene expressions of 4E-BP2 and S6K1 in the muscle of gibel carp. The present results indicate that dietary leucine led to a marked tissue-specific response on protein content in the muscle and hepatopancreas of gibel carp that is related to the TOR signalling pathway.

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Dietary arginine requirement for gibel carp (Carassis auratus gibelio var. CAS III) reduces with fish size from 50g to 150g associated with modulation of genes involved in TOR signaling pathway

Cited by 64 publications

References 69 publications

Nutrient Sensing Systems in Fish: Impact on Food Intake Regulation and Energy Homeostasis

Nutrient Sensing Systems in Fish: Impact on Food Intake Regulation and Energy Homeostasis

Effects of arginine supplementation on growth performance and plasma arginine, ornithine and citrulline dynamics of rainbow trout, Oncorhynchus mykiss

Effects of dietary leucine levels on growth, tissue protein content and relative expression of genes related to protein synthesis in juvenile gibel carp (Carassius auratus gibeliovar. CAS III)

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