Dietary Antioxidant and Oxidative Stress: Interaction between Vitamins and Genetics

Marcadenti, Aline; Lopes, Cristina Videira; Coelho, Andreia

doi:10.15226/jnhfs.2015.00138

Cited by 13 publications

(10 citation statements)

References 46 publications

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“…The synergism of these nutrient compounds may be effective to stimulate the activity of antioxidant enzymes; these appear to be of great importance for controlling the effects of reactive oxygen species (Marcadenti and Assis Coelho, 2015). Zinc is an essential cofactor of the Cu/Zn-SOD enzyme, catalyzes the dismutation of superoxide radicals (O 2 •− ) into the less harmful O 2 and H 2 O 2 , which can then be detoxified by catalase and glutathione peroxidase.…”

Section: Discussionmentioning

confidence: 99%

The Galohgor Nutraceutical Cookies Effects on β-Carotene Serum and Oxidative Stress of Postpartum Mothers

Ma’rifah

Roosita

Sinaga

2019

pnf

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The aim of the present study was to analyze the galohgor nutraceutical cookies effects on β-carotene serum levels and oxidative stress of postpartum mothers. To this end, a post-controlled experiment was carried out. Nineteen subjects were recruited to receive 40 g of galohgor cookies (GC) or control cookies (CC) daily for 14 days. Analysis of covariance was applied to assess the effect of the intervention. The results showed that β-carotene serum concentrations were significantly higher in the GC group compared with the CC group (0.141±0.094 μmol/L vs. 0.106±0.051 μmol/L, P<0.05). Meanwhile, malondialdehyde levels of GC group was significantly lower than that of the CC group (0.82±0.25 nmol/L vs. 0.93±0.27 nmol/L, P<0.05). These results suggest that galohgor nutraceutical may have beneficial effects on improving β-carotene serum levels and oxidative stress of postpartum mothers.

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Section: Discussionmentioning

confidence: 99%

The Galohgor Nutraceutical Cookies Effects on β-Carotene Serum and Oxidative Stress of Postpartum Mothers

Ma’rifah

Roosita

Sinaga

2019

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“…Previous studies have shown that antioxidants may act directly or indirectly in the neutralization of free radicals [19]. Antioxidant compounds are present both in organisms and in food intake (20).…”

Section: Discussionmentioning

confidence: 99%

Potential Role of Red Palm Oil Supplemented Diet on Oxidative Stress Enzymes inPlasmodium BergheiInduced Malaria

Adeleke¹,

Adejumobi

Akinola

et al. 2021

Preprint

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BackgroundMalaria parasites are very vulnerable to oxidative stress during the part of their life cycle when they inhabit the erythrocytes. Studies have shown that dietary intake of antioxidant plays a role in stabilizing oxidative stress.MethodsThe objective of this research work was to examine the antioxidative effect of red palm oil on Plasmodium berghei malaria induced oxidative stress. Sixty (60) mice were distributed into five groups. Group A served as the negative control (healthy mice with normal feed); group B as positive control (healthy mice fed with red palm oil without malaria parasite.while the other groups (C to E) served as the test groups. Group C served as group of healthy mice fed with red palm oil (pelletized), infected with malaria parasite without antimalaria drug. Group D served as group of healthy mice fed with red palm oil (pelletized), infected with malaria parasite and treated with amodiaquine. Group E served as group of healthy mice fed with normal feed, infected with malaria parasite and treated with amodiaquine. The parasitemia levels were estimated on days 1,4 and 5. The activity of oxidative stress enzymes biomarkers were determined spectrophotometrically.ResultGroup A showed a statistically significant increase in the activity of SOD (1.90 ± 0.16 units/mg protein), GST (1.68 ± 0.086 units/L) compared to group C, SOD (3.54 ± 0.83 units/mg protein), GST (2.12 ± 0.20 units/L). Group B showed a statistical significant decrease in the activities of SOD (3.22 ± 0.33 units/mg protein), Catalase (49.11 ± 2.35 µmol/min), GSH-R (31.50 ± 2.48 units/L) compared to group E, SOD (2.18 ± 0.39 units/mg protein), Catalase (44.07 ± 3.88 µmol/min), GSH-R (27.75 ± 1.64 units/L).ConclusionThe dietary intake of red palm oil helps to reduce free radical mediated injury to the tissue thus preventing oxidative stress induced by malaria or any other factors.

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“…Many studies show that endogenous antioxidants help decrease the oxidative damage directly via reacting with free radicals or indirectly by inhibiting the activity or expression of free radical generating enzymes or enhancing the activity or expression of intracellular antioxidant enzymes [25,26]. Studies show that exogenous dietary supplements such as vitamin C, E, or herbs, which are rich in flavonoids and phenols, play a major role in improving the endogenous antioxidant pool in the body and thus decrease oxidative stress [34,55,56]. Results of the present study also show that supplementation of choline with DHA or CTR during PMSS in rat pups have a long-lasting influence on increasing thiol levels through aging.…”

Section: Discussionmentioning

confidence: 99%

Persistent attenuation of brain oxidative stress through aging in perinatal maternal separated rat pups supplemented with choline and docosahexaenoic acid or Clitoria ternatea aqueous root extract

Almeida¹,

Kamath

Shenoy³

et al. 2018

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Dietary Antioxidant and Oxidative Stress: Interaction between Vitamins and Genetics

Cited by 13 publications

References 46 publications

The Galohgor Nutraceutical Cookies Effects on β-Carotene Serum and Oxidative Stress of Postpartum Mothers

The Galohgor Nutraceutical Cookies Effects on β-Carotene Serum and Oxidative Stress of Postpartum Mothers

Potential Role of Red Palm Oil Supplemented Diet on Oxidative Stress Enzymes inPlasmodium BergheiInduced Malaria

Persistent attenuation of brain oxidative stress through aging in perinatal maternal separated rat pups supplemented with choline and docosahexaenoic acid or Clitoria ternatea aqueous root extract

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