Dietary administration of natural immunostimulants on growth performance, haematological, biochemical parameters and disease resistance of Asian Sea bass<i>Lates calcarifer</i>(Bloch, 1790)

Devakumar, Chandhirasekar; Chinnasamy, Arulvasu

doi:10.1111/are.12955

Cited by 12 publications

(7 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Leucocytosis, also reported by Jantrarotai and Lovell (1990), attributed the cause of leucocytosis as a rejoinder to the necrosis of gastric glands. However, the aflatoxin group treated with lipopolysaccharides showed significant improvement in the haematological markers up to the average control level; these results were in harmony with Devakumar and Chinnasamy (2017), who stated that fish supplied with lipopolysaccharides revealed a substantial upsurge in erythrogram. Hannun and Linardic (1993) show the mechanism of how mycotoxins suppress an inflammatory response.…”

Section: Discussionsupporting

confidence: 81%

Ameliorative effect of dietary lipopolysaccharides on Oreochromis niloticus juveniles submitted to aflatoxin B1‐induced oxidative stress and bacterial challenge

El‐Kader¹,

Shukry

Dawood³

et al. 2021

Aquaculture Research

View full text Add to dashboard Cite

The current study was designed to evaluate the ameliorative effect of lipopolysaccharides (LPS) (a portion of the Gram -ve bacteria cell wall) on aflatoxin (AFB1)-persuaded changes in the cytokine expression, heat-shock protein 70 (HSP70), antioxidant genes, different haematological and biochemical parameters in Nile Tilapia along with the infection by Aeromonas hydrophila and the immune-stimulant efficiency of LPS on the growth pattern. For this study, two hundred and forty O. niloticus (35 ± 1.5 g) were used. The fish were randomly allocated into four experimental groups, four replicates for each group (15 fish/replicate). Group 1 was the negative control group fed on a basal diet, and group 2 was the positive control group fed on the basal diet with aflatoxins (AFB1) 200 µg/kg feed. Group 3 has fed the lipopolysaccharides 20 mg/100 gm diets. Group 4, besides the AFB1-contaminated basal diet, was provided with lipopolysaccharides 20 mg/100 gm diet. At the end of the 12 weeks, each group was injected with A. hydrophila. The analysis revealed that LPS-treated AFB1supplemented fish showed improvement in haematological, lysosomal and phagocytic activities and total protein and significantly decreased liver enzyme exaggerated by aflatoxin; alongside, the LPS-treated aflatoxin-supplemented fish revealed a significant effect on the haematological and the immunity markers after 24 h, 48 h and 1 week post challenged with A. hydrophila. Concerning the gene expression, AFB1 group showed significant up-regulation of HSP70 and interferon gamma gene mRNA expression, which is significantly down-regulated by LPS treatment, besides LPS showed up-regulation of catalase and superoxide dismutase genes markedly alongside with interleukins (IL), IL-8 and IL-1B; the binding effect of LPS markedly appears after A. hydrophila which significantly modulates the HSP70 and immunity marker genes in addition to the antioxidant-related genes, CAT and SOD. Histopathological findings reflected a marked increase in intestinal villi length in LPS-treated groups.Our view illuminates for the first time the pathways of molecular wellness for the role of LPS in AFB1 toxicity and bacterial infection. Our observation illuminates the | 3661 ABD EL-KADER Et AL.

show abstract

Section: Discussionsupporting

confidence: 81%

Ameliorative effect of dietary lipopolysaccharides on Oreochromis niloticus juveniles submitted to aflatoxin B1‐induced oxidative stress and bacterial challenge

El‐Kader¹,

Shukry

Dawood³

et al. 2021

Aquaculture Research

View full text Add to dashboard Cite

show abstract

“…Immunostimulants, which are feed additives derived from natural sources or synthetically, are capable of modulating the fish immune response and improving disease resistance. Therefore, people have begun to consider the immune stimulants used in the aquaculture industry [ 10 , 11 ]. Due to the low toxicity, small side effects, and little residue, increasing attention has been paid to herbs as environmentally friendly immunostimulants, and many studies have shown that herbs play a positive role in the prevention and treatment of fish diseases [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies have explored the effects of plant or herbal, such as garlic, hirami lemon, and leaf meal, extracts as feed additives on the rearing performance of L. calcarifer , and positive effects in terms of growth and immunity have been observed (faster growth, higher disease resistance. and lower mortality rates) [ 4 , 9 , 10 ]. In this study, G. uralensis was used as the feed additive to test the immune responses of L. calcarifer .…”

Section: Introductionmentioning

confidence: 99%

Immune Responses of Asian Seabass Lates calcarifer to Dietary Glycyrrhiza uralensis

Yang

Han

et al. 2020

Animals

View full text Add to dashboard Cite

To understand the impacts of dietary Glycyrrhiza uralensis on the immune responses of Lates calcarifer, the expression of immune-related genes including crp, c-3, c-4, mtor, mlst-8, eif4e, hsp-70, hsp-90, il-8il-8, il-10, tgfβ1, tnf, ifn-γ1, and mxf in L. calcarifer juveniles was evaluated in this study. Fish were fed experimental diets with G. uralensis levels of 0%, 1%, 3%, and 5% for 56 days. The results showed that dietary G. uralensis could improve the growth and survival of L. calcarifer and regulate the immune-related genes’ expression in L. calcarifer. Dietary G. uralensis significantly upregulated the expression level of crp, mtor, hsp-90, c-3, and c-4 genes in the liver of L. calcarifer, while hsp-70 gene expression was nearly downregulated. It did not upregulate the expression of elf4e and mlst-8 in the 1% and 3% inclusion groups, but it was the exact opposite in the 5% inclusion group. G. uralensis significantly affected the expression of il-8, il-10, tnf, ifn-γ1, mxf, and tgfβ1 in the head kidney of L. calcarifer. G. uralensis upregulated the expression of tnf and tgfβ1 consistently, but ifn-γ1 was at a low expression level. The expression of il-8 and il-10 was upregulated in the 1% group, while it was downregulated in the 5% group. The results from the present study indicate that dietary G. uralensis appeared to improve the immune function of L. calcarifer, and the optimum inclusion level should be between 1–3%.

show abstract

“…These medicinal plants can either indirectly impact the cultured fish by strengthening the immune system and/or directly influence the host and its functions and processes to improve its physiological performance (Adel, Dawood, Shafiei, Sakhaie, & Hosseini Shekarabi, 2020; Awad, El‐Fiqi, Austin, & Lyndon, 2020; Gholamhosseini et al., 2020; Van Hai, 2015). Great efforts have been devoted to medicinal plants in regulating the fish immune response if either infection or stress happens (Devakumar & Chinnasamy, 2017; Ghehdarijani, Hajimoradloo, Ghorbani, & Roohi, 2016; Saeidi Asl, Adel, Caipang, & Dawood, 2017; Wang, Sun, Liu, & Xue, 2017). Furthermore, some studies reported that simultaneous use of supplements and medicinal plants can enhance development process and increase the effective rearing of aquatic animals (Adel, Abedian Amiri, Zorriehzahra, Nematolahi, & Esteban, 2015; Adel, Safari, Pourgholam, Zorriehzahra, & Esteban, 2015; Ahmadniaye Motlagh, Sarkheil, Safari, & Paolucci, 2020; Fadl et al., 2020; Zakęś et al., 2008; Zhang et al., 2020).…”

Section: Introductionmentioning

confidence: 99%

The potential benefits of Mentha longifolia on growth performance and innate immunity parameters in Caspian kutum ( Rutilus frisii kutum )

et al. 2020

View full text Add to dashboard Cite

The current research was conducted to examine the benefits of Mentha longifolia (ML) administration through diet on growth performance and haematological, biochemical, and immunological parameters of Caspian kutum (Rutilus frisii kutum). Fish with average weight of 3 g were fed for 8 weeks with diets supplemented with 0%, 2%, 4% and 6% ML‐extract. Feeding with 6% ML for 8 weeks significantly improved the growth performance. The highest values in total protein content, protease and esterase activities were observed in the 6% ML. Feeding with 4% and 6% ML led to a significant increase in the alternative complement, respiratory burst activities and total immunoglobulins in blood as well as lysozyme activity in the mucus and serum. The enhancement of skin mucus immune parameters was observed in fish fed with dietary (≥4%) ML supplement. The mucosal antibacterial effects revealed that the highest ML concentration (6%) had the maximum bacterial growth inhibition zone diameter (mm) and MIC compared with other groups in the study. White blood cell numbers and haematocrit values were significantly higher than in the control groups following the use of 4% and 6% ML. The highest red blood cell counts resulted from the use of 6% ML. Although 4% and 6% ML led to a decrease in the number of lymphocytes, the neutrophils increased after using the same dose, compared with the control group. Triglycerides levels significantly decreased in fish fed with 4% and 6% ML; however, no significant changes were observed in other blood biochemical parameters. Thus, it can be concluded that diets supplemented with ML‐extract could significantly impact Caspian kutum by improving growth performance and boosting their immune response.

show abstract

Dietary administration of natural immunostimulants on growth performance, haematological, biochemical parameters and disease resistance of Asian Sea bassLates calcarifer(Bloch, 1790)

Cited by 12 publications

References 51 publications

Ameliorative effect of dietary lipopolysaccharides on Oreochromis niloticus juveniles submitted to aflatoxin B1‐induced oxidative stress and bacterial challenge

Ameliorative effect of dietary lipopolysaccharides on Oreochromis niloticus juveniles submitted to aflatoxin B1‐induced oxidative stress and bacterial challenge

Immune Responses of Asian Seabass Lates calcarifer to Dietary Glycyrrhiza uralensis

The potential benefits of Mentha longifolia on growth performance and innate immunity parameters in Caspian kutum ( Rutilus frisii kutum )

Contact Info

Product

Resources

About