Diet and uterine myomas

Chiaffarino, Francesça; Parazzini, Fabio; Vecchia, Carlo La; Chatenoud, Liliane; Cintio, Elisabetta Di; Marsico, Silvia

doi:10.1016/s0029-7844(99)00305-1

Cited by 90 publications

(89 citation statements)

References 15 publications

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“…This observation is similar to other studies 14,15 .Increased BMI and tubal sterilisation were found to be risk factors in some studies. Our study do not show any association for these risk factors 8,16 .…”

Section: Discussioncontrasting

confidence: 90%

Epidemiological Risk Factors For Fibroid Uterus -A Case Control Study From Kerala

B¹

2017

jmscr

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Section: Discussioncontrasting

confidence: 90%

Epidemiological Risk Factors For Fibroid Uterus -A Case Control Study From Kerala

B¹

2017

jmscr

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“…In a case-control study in Italy (Chiaffarino et al 1999), a moderate association was found between the risk of uterine myomas and the consumption of beef, other red meat, and ham, whereas a high intake of green vegetables seemed to have a protective effect. Unfortunately, no estimate of the total caloric intake was obtained, and no attempt was made to estimate the amount of fat in the diet for cases and controls, although one might assume that a higher intake of beef would be associated with a greater amount of fat in the diet.…”

Section: Dietmentioning

confidence: 96%

“…Despite the limitations of the study, the results are interesting and raise a number of issues. Because fibroids are known to be hormonally responsive tumors, are the dietary risks noted above (Chiaffarino et al 1999) secondary to the effects of various food groups upon the bioavailability of estrogen or progesterone? Is the protective effect of a high intake of green vegetables related to the fiber, some other undetermined component, such as a vitamin, or a corresponding reduction of fat in the diet?…”

Section: Dietmentioning

confidence: 99%

Etiology and pathogenesis of uterine leiomyomas: a review.

Flake

Andersen

Dixon

2003

Environ Health Perspect

494

392

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Uterine leiomyomas, or fibroids, represent a major public health problem. It is believed that these tumors develop in the majority of American women and become symptomatic in one-third of these women. They are the most frequent indication for hysterectomy in the United States. Although the initiator or initiators of fibroids are unknown, several predisposing factors have been identified, including age (late reproductive years), African-American ethnicity, nulliparity, and obesity. Nonrandom cytogenetic abnormalities have been found in about 40% of tumors examined. Estrogen and progesterone are recognized as promoters of tumor growth, and the potential role of environmental estrogens has only recently been explored. Growth factors with mitogenic activity, such as transforming growth factor-β 3, basic fibroblast growth factor, epidermal growth factor, and insulin-like growth factor-I, are elevated in fibroids and may be the effectors of estrogen and progesterone promotion. These data offer clues to the etiology and pathogenesis of this common condition, which we have analyzed and summarized in this review.

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“…One study [31] has specifically addressed the question of dietary influences on the prevalence of fibroids. In an Italian population, 843 women with fibroids were compared with 1557 women without.…”

Section: Diet and Fibroidsmentioning

confidence: 99%