Diet and other factors in the aetiology of diverticulosis: an epidemiological study in Greece.

Manousos, O. N.; Day, Nicholas E.; Τζώνου, Αναστασία; Papadimitriou, Ch.; Kapetanakis, Anargyros; Polychronopoulou-Trichopoulou, Antonia; Trichopoulos, D.

doi:10.1136/gut.26.6.544

Cited by 145 publications

(95 citation statements)

References 17 publications

(4 reference statements)

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“…Finally, the necropsy data also indicate that DD is more prevalent in women than men ( Figure 1B). It is not yet clear as to whether this gender effect is related to hormonal or anthropometric risk factors, although Manousos et al [12] report a relationship with parity.…”

Section: Epidemiology and Public Health Impactmentioning

confidence: 93%

“…These studies are summarized in Table 2 and in general support the dietary fiber hypothesis. Two of the three case-control studies [12,62] and the only prospective case-control study [63] , found lower dietary fiber consumption amongst cases vs controls. In contrast, [12] Prevalence of DD assessed by barium enema in 189 non-vegetarian volunteers vs 55 vegetarians Diverticular disease was significantly higher in the non-vegetarian group "Asymptomatic" volunteers recruited prior to diagnosis and grouped based on dietary choices.…”

Section: Contractionary Cholinergic Stimulimentioning

confidence: 99%

“…Two of the three case-control studies [12,62] and the only prospective case-control study [63] , found lower dietary fiber consumption amongst cases vs controls. In contrast, [12] Prevalence of DD assessed by barium enema in 189 non-vegetarian volunteers vs 55 vegetarians Diverticular disease was significantly higher in the non-vegetarian group "Asymptomatic" volunteers recruited prior to diagnosis and grouped based on dietary choices. A potential confounder is a possible causative effect for meat Gear et al [104] Case control study comparing dietary fiber intake in 40 (symptomatic) DD cases vs 80 age and sex matched controls Dietary fiber intake significantly higher amongst controls…”

Section: Contractionary Cholinergic Stimulimentioning

confidence: 99%

“…Unfortunately, there appears to be no published data on obesity and asymptomatic DD. Additional lifestyle risk factors emerging from the literature are: high red meat consumption [12,64] , increasing socio-economic status in a Greek cohort [12] , hypertension [65] , parity [12] and low physical activity with increased symptomatic disease [63] . The evidence base for these risk factors is even less vigorous than it is for dietary fiber.…”

Section: Bread and Cereal Productsmentioning

confidence: 99%

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Diet, ageing and genetic factors in the pathogenesis of diverticular disease

Commane¹,

Arasaradnam²,

Mills³

et al. 2009

WJG

116

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Diverticular disease (DD) is an age-related disorder of the large bowel which may affect half of the population over the age of 65 in the UK. This high prevalence ranks it as one of the most common bowel disorders in western nations. The majority of patients remain asymptomatic but there are associated life-threatening co-morbidities, which, given the large numbers of people with DD, translates into a considerable number of deaths per annum. Despite this public health burden, relatively little seems to be known about either the mechanisms of development or causality. In the 1970s, a model of DD formulated the concept that diverticula occur as a consequence of pressureinduced damage to the colon wall amongst those with a low intake of dietary fiber. In this review, we have examined the evidence regarding the influence of ageing, diet, inflammation and genetics on DD development. We argue that the evidence supporting the barotrauma hypothesis is largely anecdotal. We have also identified several gaps in the knowledge base which need to be filled before we can complete a model for the etiology of diverticular disease.

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Section: Epidemiology and Public Health Impactmentioning

confidence: 93%

Section: Contractionary Cholinergic Stimulimentioning

confidence: 99%

Section: Contractionary Cholinergic Stimulimentioning

confidence: 99%

Section: Bread and Cereal Productsmentioning

confidence: 99%

See 2 more Smart Citations

Diet, ageing and genetic factors in the pathogenesis of diverticular disease

Commane¹,

Arasaradnam²,

Mills³

et al. 2009

WJG

116

View full text Add to dashboard Cite

show abstract

“…In Western countries, it is estimated to be present in approximately 30% of people of age 60 and 60% of people older than age 80 [1]. It also increases with the patient who is on NSAID [3][4][5], low fiber diet [3,6,7], smoking [3,8] , opiates [3,9,10], alcohol [11,12] and immunocompromized [3,13].…”

Section: Introduction and Overviewmentioning

confidence: 99%

Case Report: Unusual Presentation of Complicated Diverticulitis at Colostomy Site

Alasari

Kim²

2012

TOCOLCJ

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we report a case of a 75 years old male diagnosed on 2006 with a low rectal cancer and operated with an abdominoperineal resection procedure at that time. Since then, he was doing fine with his end colostomy until 29/07/2011, when he was presented with stoma site redness, pain, tenderness and fever with loose stool; the CT scan showed a distal colon and stoma diverticulitis and abscess lateral to stoma; the patient was managed with drainage, soft diet and antibiotic till it resolved and he was discharged home in a healthy condition.

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