Diet and haemostatic processes

Vorster, Hester H.; Jerling, Johann C.

doi:10.1079/nrr19970007

Cited by 20 publications

(7 citation statements)

References 127 publications

(63 reference statements)

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“…Several dietary intervention studies have shown that FVII is influenced by the diet [64][65][66][67], and total dietary fat intake appears to be the main determinant of postprandial FVII coagulant activity (FVIIc) [68]. One effect of olive oil, a fundamental component of MeD, is on FVII, a key protein in thrombosis and an important risk factor for ischemic heart disease [69][70][71][72][73].…”

Section: Monounsaturated Fatty Acids and Factor Vii: Anti-thrombotic mentioning

confidence: 99%

Vascular effects of the Mediterranean diet Part I: Anti-hypertensive and anti-thrombotic effects

Capurso

Massaro

Scoditti

et al. 2014

Vascular Pharmacology

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Section: Monounsaturated Fatty Acids and Factor Vii: Anti-thrombotic mentioning

confidence: 99%

Vascular effects of the Mediterranean diet Part I: Anti-hypertensive and anti-thrombotic effects

Capurso

Massaro

Scoditti

et al. 2014

Vascular Pharmacology

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“…n -3 PUFA is famous for its protective and modifying effects on a variety of diseases such as multiple sclerosis, major depression, atherosclerosis, ventricular arrhythmia and inflammatory or autoimmune diseases ( Nuernberg et al, 2005a ; Balk et al, 2006 ), and CLAs have been reported to be beneficial to human health because of their health-promoting properties such as the inhibition of carcinogenesis, a reduced rate of fat deposition, stimulation of the immune system, and reduced serum lipids in animal models ( Banni et al, 2002 ; Wu, 2004 ). However, an excessive consumption of SFAs such as C12:0, C14:0 and C16:0 may cause an atherogenic potential in humans ( Vorster et al, 1997 ) and may contribute to high coronary heart disease (CHD) mortality rates ( Williams, 2000 ; Rioux and Legrand, 2007 ). Additionally, a high proportion of n -6 PUFA can be deleterious for human health ( de Deckere et al, 1998 ).…”

Section: Introductionmentioning

confidence: 99%

Influence of Restricted Grazing Time Systems on Productive Performance and Fatty Acid Composition of <i>Longissimus dorsi</i> in Growing Lambs

Wang

Chen

Luo

et al. 2015

Asian Australas. J. Anim. Sci

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Fifty 3-month-old male Tan lambs (similar in body weight) were divided into 5 groups to investigate the effects of different restricted pasture grazing times and indoor supplementation on the productive performances and fatty acid composition of the intramuscular fat in growing lambs. The lambs grazed for different periods of time (12 h/d, 8 h/d, 4 h/d, 2 h/d, and 0 h) and received various amounts of supplementary feedings during the 120-day trial. Pasture dry matter intake (DMI), total DMI, average daily gains and the live body weights of the lambs were measured during the experiment. The animals were slaughtered at the end of the study, their carcass traits were measured, and their longissimus dorsi muscles were sampled to analyze the intramuscular fat (IMF) content and fatty acid profiles. The results indicated that the different durations of grazing and supplementary feedings affected the animal performances and the composition of fatty acids. Grazing for 8 h/d or 2 h/d with the corresponding supplementary concentrate resulted in lambs with higher body weights, carcass weights and IMF contents. Lambs with longer grazing times and less concentrate accumulated more healthy fatty acids such as conjugated linoleic acid and n-3 polyunsaturated fatty acid and had higher n-3/n-6 ratios. Overall, a grazing allowance of 8 h/d and the corresponding concentrate was recommended to maintain a high quantity and quality of lamb meat.

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“…A recent review showed that prudent low fat, high fibre diet with the maintenance of ideal body weight might temper haemostatic risk factor for cardiovascular disorders [13]. In recent studies on African vegetarians, we found decreased BP, fibrinogen level and plasma viscosity [14,15], which we concluded may reduce predisposition of African vegetarians to major complications of CVD/IHD.…”

Section: Introductionmentioning

confidence: 47%

Fruits and vegetables moderate blood pressure, fibrinogen concentration and plasma viscosity in Nigerian hypertensives

Adebawo¹,

Ba²,

Adeyanju³

et al. 2007

AJFAND

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Fruits and vegetables contain vital components such as potassium, antioxidants, vitamins and folic acid that might contribute to lowering blood pressure which is a major risk factor in cardiovascular disorders. However, the results of the few investigations on the correlation between intake of fruits and vegetables and cardiovascular disease have been inconsistent. Worse still, there is dearth of information on disease prevention with fruits and vegetables in Africans. Thus, we investigated the relative effect of fruits and vegetables on blood pressure, viscosity of blood and fibrinogen level. Ten weeks intervention study with ≥ 3 times daily consumption of fruits and vegetables by hypertensive patients was conducted. The fruits and vegetables included in the test diet were oranges, banana, pawpaw, mango, pineapple, grape, tangerine, garden egg, okra, pumpkin leaf, spinach, amaranthus and water leaf. The patients were allowed to consume the food servings while their eating habit was not restricted. Blood pressure, blood viscosity and plasma fibrinogen and nutrient intake were determined before and during intervention. The complementary fruits and vegetables included in the normal dietary regimen of the patients during the 10 weeks study increased the levels of potassium, calcium, phosphorus, antioxidants and dietary fiber significantly compared to the baseline values (P<0.01). The systolic and diastolic blood pressure were significantly lowered; percentage differences of -9.01 and -3.73 (P<0.01) respectively were observed after 10 weeks. Percentage differences of -6.02, -38.86 and -5.29 (P<0.05.) were observed for haematocrit, blood viscosity and plasma fibrinogen respectively compared with the base line. Fruits and vegetables lowered the systolic and diastolic blood pressure, blood viscosity and plasma fibrinogen. The decrease in haematocrit and fibrinogen could influence reduction in blood viscosity thereby preventing premature CVD in hypertensive. Daily intake of fresh fruit and vegetable might be beneficial for the prevention and as therapeutic regime for cardiovascular complications.

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Diet and haemostatic processes

Cited by 20 publications

References 127 publications

Vascular effects of the Mediterranean diet Part I: Anti-hypertensive and anti-thrombotic effects

Vascular effects of the Mediterranean diet Part I: Anti-hypertensive and anti-thrombotic effects

Influence of Restricted Grazing Time Systems on Productive Performance and Fatty Acid Composition of <i>Longissimus dorsi</i> in Growing Lambs

Fruits and vegetables moderate blood pressure, fibrinogen concentration and plasma viscosity in Nigerian hypertensives

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