Dielectric heating of highly corrosive and oxidizing reagents on a hybrid glass microfiber–polymer centrifugal microfluidic device

Abstract

Many assays necessitate the use of highly concentrated acids, powerful oxidizing agents, or a combination of the two. Although microfluidic devices offer vast potential for rapid analytical interrogation at the...

Integrated membranes within centrifugal microfluidic devices: a review

“…37 Less sensitive to flow rate than ELISA assays, colorimetric chemosensors have made use of both end-point 188,308,309 as well as encounter flow. 89 Johnson et al employed novel optode membranes containing chromoionophores to detect potassium ions in a centrifugal microfluidic device which further implemented calibration steps to eliminate measurement variability between devices. End-point detection in particular avoids the need for flow rate optimization by allowing ample time for reactants to interact.…”

“…87 Silicates can additionally be prepared in a variety of form factors, 88 including nano-or microfibers (Fig. 6F), 89 thin films (Fig. 6C), 90,91 nanotubes, 92 or as embedded colloids.…”

“…Membranes offer a reagent integration strategy that can be particularly amendable to standard manufacturing procedures. Three main approaches exist for this purpose: direct incorporation of the desired reagent by way of membrane submersion, infusion, or deposition, 89,188,264 valved retainment, 244 or functionalization for in situ production with the supply of substrate. 265 In the first scenario, reagents can either be desiccated or lyophilized and pre-concentrated for later resuspension, physically isolated as a liquid for later recovery, or allowed to perfuse passively for slow, continuous release over time.…”

A capillary-based centrifugal indicator equipped with in situ pathogenic bacteria culture for fast antimicrobial susceptibility testing

“…The centrifugal-based microfluidic AST platforms have recently emerged as an attractive technique, which could effectively address this deficiency. [30][31][32][33][34] Xu et al developed a centrifugal microfluidic concentrator, which could condense the bacteria into the microchannel tip from the milliliter bacteria suspension. 35 After a 3 h micro-cultivation on-chip, the AST for the enriched bacteria could be completed by fluorescence microscope imaging.…”

High-fidelity synthesis of microhole templates with low-surface-energy-enabled self-releasing photolithography

“…11,12 SU8 templates with micro-posts were utilized for nanoparticle tracking under optical microscope at biomolecular and cellular levels. 13 Beyond the use in fabrication, structured templates are also incorporated into microuidic system to act as key components such as separators, 14,15 multiplexors, 16 and controllable interconnects for different channels/levels of microuidic arrays. 17 Advance of fabrication technology has continually driven the evolution of template modality.…”