Integrated membranes within centrifugal microfluidic devices: a review

Abstract

Membranes represent a powerful technology for numerous lab-on-a-disc applications. This review provides a comprehensive introduction to these versatile materials as well as strategies for their integration within centrifugal microdevices.

Chemical Trends in Sample Preparation for Nucleic Acid Amplification Testing (NAAT): A Review

“…The eluent was then combined with RPA reagent in a droplet-based system, enabling quantification through digitization. Amidst the range of micro-scale fluid handling approaches, centrifugal, or so-called lab-on-a-disc platforms, have the advantage of providing a wide range of fluidic operations without the need for more equipment than a compact motor to rotate the device [152], with an excellent review focusing on the valving operation published elsewhere [153]. Considering the multistep workflow required for NA testing, it is not surprising that centrifugal devices have become a popular platform for NA testing.…”

High-fidelity synthesis of microhole templates with low-surface-energy-enabled self-releasing photolithography

“…11,12 SU8 templates with micro-posts were utilized for nanoparticle tracking under optical microscope at biomolecular and cellular levels. 13 Beyond the use in fabrication, structured templates are also incorporated into microfluidic system to act as key components such as separators, 14,15 multiplexors, 16 and controllable interconnects for different channels/levels of microfluidic arrays. 17…”

A capillary-based centrifugal indicator equipped with in situ pathogenic bacteria culture for fast antimicrobial susceptibility testing

“…The centrifugal-based microfluidic AST platforms have recently emerged as an attractive technique, which could effectively address this deficiency. 30–34 Xu et al developed a centrifugal microfluidic concentrator, which could condense the bacteria into the microchannel tip from the milliliter bacteria suspension. 35 After a 3 h micro-cultivation on-chip, the AST for the enriched bacteria could be completed by fluorescence microscope imaging.…”