Die Hornhautsensibilit�t nach Lichtkoagulation bei diabetischer Retinopathie

Abstract

Corneal sensitivity was determined with the Draeger aesthesiometer in 39 patients with proliferative diabetic retinopathy who underwent treatment with a xenon photocoagulator or argon laser. In 29 patients measurements were performed before and after photocoagulation; in 10 patients the unaffected eye was used for comparison. Statistical evaluation showed a significant difference between the mean values for corneal touch threshold before and after argon laser coagulation. After xenon photocoagulation, corneal sensitivity was reduced in all patients (n = 7). It was shown that corneal sensitivity was significant lower after xenon photo coagulation than with argon laser coagulation.

Inflammation mechanism and anti-inflammatory therapy of dry eye

“…Panretinal laser therapy can affect corneal neuropathy and cause dry eye ( 44 ). In diabetic patients, meibomian gland duct obstruction, acinar atrophy, and surrounding inflammatory manifestations lead to meibomian gland dysfunction and dry eye ( 45 ). In the urea chain within induced diabetic rats, the lacrimal gland weight and volume are lower, while inflammation and related factors such as IL, TNF, and AGE were higher than in the control ( 46 ).…”