Die Entwicklung des Cortischen Organs beim Meerschweinchen

Thorn, Lieselotte

doi:10.1007/978-3-642-66160-0

Cited by 5 publications

(5 citation statements)

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“…The change in shape of the hair cells has also been reported by Thorn (1975) in the guinea pig, Pujol and Marty (1970) in the cat and Lenoir et al (1980) in the rat, and so far seems to be a common feature during the maturation of the receptor cells. The change in shape of the hair cells has also been reported by Thorn (1975) in the guinea pig, Pujol and Marty (1970) in the cat and Lenoir et al (1980) in the rat, and so far seems to be a common feature during the maturation of the receptor cells.…”

Section: Hair Cell Receptorssupporting

confidence: 52%

Postnatal development of the rat organ of Corti

1992

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The development of cochlear receptor cells and their supporting elements was studied by means of semi-thin and ultra-thin sections during the first postnatal weeks in the rat. The temporal and spatial patterns of the receptor cell development were investigated between the 4th and 24th days after birth. At approx. ten equidistant positions along the entire cochlear duct length of inner and outer hair cells, width of outer hair cell triad and stereocilia-length of the outer hair cells were quantitatively analyzed. Striking maturational changes take place before the 12th day after birth, that is, when the onset of hearing occurs. These changes are the formation of the tunnel of Corti, of the Nuel spaces, the appearance of filaments within the supporting elements and the change in cell shape of the hair cells. Between 4 days and 20 days after birth the maturation of outer hair cells is characterized by a decrease of organelles in the cytoplasm and establishment of the subsurface cistern. The quantitative analysis revealed a unique developmental pattern of the length of the outer hair cells, the width of the outer hair cell triad and the stereocilia length of the outer hair cells. Shortly after birth these structures have an almost constant size along the whole cochlear duct, but with increasing age the structures shorten at the cochlear base and enlarge at the apex. This pattern results in the establishment of a baso-apical gradient of the above mentioned structures. We assume that this baso-apical gradient is of central importance for the frequency representation.

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Section: Hair Cell Receptorssupporting

confidence: 52%

Postnatal development of the rat organ of Corti

1992

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“…Considering that the development of the organ of Corti occurs earlier and faster in the basal turns than in the upper turns (Thorn, 1975;Weibel, 1957) a confirmed malformation of Nuel's space chiefly in the upper turns perhaps produces OHC without basal nerve endings and remnants of Deiter's cells between the OHC as seen in this study.…”

Section: Atypical Sensory Cellssupporting

confidence: 73%

“…There are striking similarities between the atypical OHC found in the upper turns and the short OHC in the basilar papilla of other vertebrate classes such as amphibia, reptilia, and aves (Baird, 1974;Jahnke et al, 1969;Lewis et al, 1985;Retzius, 1884;Takasaka and Smith, 1971;Tanaka and Smith, 1978). According to Thorn (1975), in the guinea pig no synaptic nerve endings in the basal part of OHC could be observed till day 37 of the prenatal organ of Corti, and from day 41 the Nuel's space begins to develop, forming a cleft between the upper region of Deiter's cells and OHC. Before this state OHC and Deiter's cells are in close contact.…”

Section: Atypical Sensory Cellsmentioning

confidence: 99%

Atypical cells in the normal guinea pig organ of Corti as revealed by micromanipuiation in SEM

1992

Microscopy Res & Technique

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Inner ear tissue of the normal guinea pig was conductively stained (OTOTO-method) for SEM investigations. The Hensen's cells of the organ of Corti were removed using a micromanipulator inside the SEM. By this method atypical bodies of sensory and supporting cells were revealed in the apical turns of the cochlea. Atypical sensory cells showed great variations in size and shape. Several had no contact to Deiter's cells and no or only one nerve supply at their basal end. Atypical Deiter's cells showed alterations in shape and in the form of their phalangeal processes. Additionally altered parts of the organ of Corti were isolated by micromanipulation and embedded for correlative TEM-investigations.

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“…1980Lenoir etal. 1978; guinea pig: Pujol and Hilding 1973;Thorn 1975). 1978; guinea pig: Pujol and Hilding 1973;Thorn 1975).…”

Section: Introductionunclassified

Postnatal development of the rat organ of Corti

Roth

Bruns

1992

Anat Embryol

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The development of the rat organ of Corti was studied during the first postnatal weeks. The temporal and the spatial patterns of cochlear development were investigated between 4 and 24 days after birth by means of semi-thin sections at approx. ten equidistant positions along the entire cochlear duct. At all examined positions width, thickness and cross sectional area of basilar membrane, cross-sectional area of tectorial membrane, of cells of Hensen, Claudius and Boettcher and of the organ of Corti were quantitatively analyzed. The most conspicuous maturational changes occur between 8 and 12 days after birth. These are the detachment of the tectorial membrane, the first appearance of filaments within the basilar membrane, the formation of the tunnel of Corti and the opening of the inner spiral sulcus. Quantitative analysis revealed that structures of a given position along the cochlear duct do not develop synchronously. Width of the basilar membrane and cross-sectional area of the tectorial membrane are already mature at the onset of hearing (10-12 days after birth). Length, thickness and cross-sectional area of the basilar membrane as well as cross-sectional area of the organ of Corti and of the cells of Hensen, Claudius and Boettcher still develop after the onset of hearing (up to 20-24 days after birth). We suggest that basic cochlear function is established by structures which are mature before the onset of hearing. Cochlear structures which develop after the onset of hearing might be involved in this improvement during this period.

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Die Entwicklung des Cortischen Organs beim Meerschweinchen

Cited by 5 publications

References 0 publications

Postnatal development of the rat organ of Corti

Postnatal development of the rat organ of Corti

Atypical cells in the normal guinea pig organ of Corti as revealed by micromanipuiation in SEM

Postnatal development of the rat organ of Corti

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