Die DONALD Kohorte

Abstract

The DONALD study has been conducted in Dortmund, Germany since 1985 to examine the complex relations between nutritional intake, metabolism and growth from infancy to adulthood. Every year, approximately 40 infants are newly recruited into the open cohort study. Examinations conducted at ages 3, 6, 9, 12, 18, 24 months and then annually until young adulthood, comprise anthropometry, a 3 day weighed dietary record, a 24 h urine sample (from age 3-4 years onwards), medical examinations and parental interviews. Since 2005, participants are invited for follow-up visits during adulthood (including fasting blood samples). Approximately 1,400 children have been recruited into the study up to 2010. Recent findings revealed e.g. (i) the relevance of early life factors for subsequent development of body composition and puberty timing, (ii) the relation between pubertal hormonal status and puberty onset, (iii) age and time trends in iodine status and modern dietary habits and (iv) potential furan and benzol exposition by commercial weaning foods. Future analyses will provide insight into the extent to which health in young adulthood is receptive to diet, anthropometric pattern and hormonal status in distinct potentially critical periods during childhood.

Overweight in Adolescence Can Be Predicted at Age 6 Years: A CART Analysis in German Cohorts

“…The Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study is a longitudinal open cohort study [28], [29]. Since 1985, about 35-40 newborns are annually recruited into the study examined at ages 3, 6, 9, 12 and 18 months and annually thereafter until young adulthood [28].…”

“…Since 1985, about 35-40 newborns are annually recruited into the study examined at ages 3, 6, 9, 12 and 18 months and annually thereafter until young adulthood [28]. The elaborate design of the DONALD Study results in an over-representation of children from families with high socioeconomic status.…”

Breastfeeding and Its Prospective Association with Components of the GH-IGF-Axis, Insulin Resistance and Body Adiposity Measures in Young Adulthood – Insights from Linear and Quantile Regression Analysis

“…Fourthly, the participants of the DONALD Study are characterized by a high socio-economic status as compared to the German population, which may however have reduced our vulnerability to residual confounding. It is further worthwhile mentioning that a nationwide German study on breastfeeding conducted 1997-1998 found comparable numbers with respect to prevalence and duration of breastfeeding [22] .…”

“…The DONALD Study is an ongoing, open cohort study conducted in Dortmund, Germany. Details on this study have been described elsewhere [22] , [23] . Every year, an average of 35-40 infants are newly recruited and first examined at the age of 3 months.…”

Von Nährstoffen zu Lebensmitteln und Mahlzeiten: das Konzept der Optimierten Mischkost für Kinder und Jugendliche in Deutschland

“…Bei der Gestaltung der Speisepläne dienten Verzehrdaten aus der DONALD-Studie [12] als Orientierung. Hierfür wurden aus vorliegenden 3-Tage-Wiege-Ernährungsprotokollen aus den Jahren 2007 -2014 für 3 Altersgruppen (4 -6 Jahre, 10 -12 Jahre, 15 -18 Jahre) jeweils diejenigen 10 Protokolle mit der höchsten Ernährungsqualität, gemessen an einem Nährstoffqualitätsindex [13], ausgewählt.…”