Die chirurgische Wundinfektion und ihre Bekämpfung

The Histotoxic Clostridial Infections of Man 12

“…Of these, the most important are the local pain and swelling, the severe toxemia, the destruction of muscle tissue, and (particularly in uterine infections) the appearance of jaundice, hemoglobinuria, and hemoglobinemia. Gas, it will be observed, is not in itself a diagnostic criterion of much significance; in some cases it is absent or masked by the associated oedema, in most it is manifest only when the disease is already well advanced (14,106,143,155,261,432). Moreover, gassy wounds can occur in the absence of any clostridial infection: from the explosive effect of modern missiles (685, 833); in industrial accidents, from compressed air (269); from the activities of other organisms, of which the commonest is probably E. coli (25,87,224,261,511,526,663); or from various chemical agents, e.g., certain magnesium compounds (150, 683, 894).…”

The Histotoxic Clostridial Infections of Man

“…Of these, the most important are the local pain and swelling, the severe toxemia, the destruction of muscle tissue, and (particularly in uterine infections) the appearance of jaundice, hemoglobinuria, and hemoglobinemia. Gas, it will be observed, is not in itself a diagnostic criterion of much significance; in some cases it is absent or masked by the associated oedema, in most it is manifest only when the disease is already well advanced (14,106,143,155,261,432). Moreover, gassy wounds can occur in the absence of any clostridial infection: from the explosive effect of modern missiles (685, 833); in industrial accidents, from compressed air (269); from the activities of other organisms, of which the commonest is probably E. coli (25,87,224,261,511,526,663); or from various chemical agents, e.g., certain magnesium compounds (150, 683, 894).…”