Dichomine, a Novel Type of Iboga Alkaloid*,**

Abstract

From the leaves of TABERNAEMONTANA DICHOTOMA and the leaves and twigs of T. EGLANDULOSA a new alkaloid was isolated which was assigned structure 1 on the basis of spectroscopic and chemical evidence.

Organocatalytic multicomponent coupling to access a highly functionalised tetracyclic furoindoline: interrupted Passerini/Joullié–Ugi cascade reaction

“…4 Notably, dichomine ( 6 ) has the structural features of both spiro[indoline-3,3′-pyrrolidine] and furo[2,3- b ]indoline. 5 In addition, the N–O acetal moiety of furoindoline would be a useful for further chemical transformations. Therefore, indole compounds containing both skeletons are attractive species in terms of both their biological activity and synthetic utility.…”