Diarrhea Acquired in the Hospital

McFarland, Lynne V.

doi:10.1016/s0889-8553(21)00090-x

Cited by 47 publications

(8 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, there was a significant difference in the severity of diarrhea and age, older people being more likely to develop nosocomial diarrhea, which agrees with another study that found old age as an essential risk factor [ 33 ]. Another study [ 34 ] reported an incidence of nosocomial diarrhea in 3 to 28 adults for every 100 admissions, while in elderly patients over 70 years, it was 17 to 31 for every 100 admissions. Another study identified a relative risk of 6.6, 11.8, and 14.3 for the age groups 41 to 60, 61 to 75, and over 75 years, respectively [ 34 – 35 ].…”

Section: Discussionmentioning

confidence: 99%

Assessment of the incidence and etiology of nosocomial diarrhea in a medical ward in Iraq

et al. 2022

View full text Add to dashboard Cite

This study aimed to detect the incidence, etiology, risk factors, and severity of nosocomial diarrhea among adult inpatients in a medical ward in Iraq. The study was conducted among patients admitted to the medical ward from June 1, 2019, to January 31, 2020, in AL-Sader medical city. The surveillance for nosocomial diarrhea was performed by monitoring every patient in the ward 3 times/week. 1050 patients were admitted to the medical ward in AL-Sader medical city. Of these, 52 patients (mean age 58±12.91 years, range 32 to 80) developed new-onset diarrhea during hospitalization. There was a significant relationship between the severity of diarrhea and age, residence, antibiotic use, including number and duration of antibiotics, immunosuppressive agents (steroids/chemotherapy), duration of hospital stay, level of consciousness, and enema use. Nosocomial diarrhea is a significant clinical problem that complicates about 5% of all admission in the medical ward. Various microorganisms account for nosocomial diarrhea, including E. histolytica, G. lamblia, and Candida. Several risk factors associated with the severe form of nosocomial diarrhea include old age, antibiotic use, immunosuppressive use, and length of hospital stay.

show abstract

Section: Discussionmentioning

confidence: 99%

Assessment of the incidence and etiology of nosocomial diarrhea in a medical ward in Iraq

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Environmental C. difficile may act as a source of nosocomial infection in human and veterinary hospitals, especially in patients predisposed to infection by treatment with broad-spectrum antimicrobial drugs. 26,28,36 In conclusion, the documented widespread dissemination of C. difficile spores in a veterinary teaching hospital draws attention to its potential for causing nosocomial or perhaps even zoonotic infection in this environment.…”

mentioning

confidence: 99%

“…This study documents the prevalence of this organism in the environment and its potential role in nosocomial disease.Clostridium difficile is a gram-positive anaerobic bacterium that is an important cause of diarrhea in humans, 2,22,25 and a commonly identified nosocomial pathogen in human hospitals. [26][27][28]31 Other than hamsters and guinea pigs, the exact role of this pathogen in domestic animals is less clear, although increasingly it is associated with enterocolitis in horses. 3,4,16,19,20,24,31,33 Clostridium difficile is implicated in approximately 20-25% of cases of enterocolitis in adult horses and foals at the Ontario Veterinary College.…”

mentioning

confidence: 99%

“…11 Spores also are relatively resistant to most common disinfectants, 36 making C. difficile a hardy environmental contaminant. Nosocomial spread of C. difficile is a well-recognized problem in human hospitals [26][27][28]31 and chronic care facilities. 5 This pathogen is among the most important nosocomial infections in humans 28 and is the most diagnosed cause of antibiotic-associated colitis.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Isolation of EnvironmentalClostridium Difficilefrom a Veterinary Teaching Hospital

2000

View full text Add to dashboard Cite

An environmental survey of a veterinary teaching hospital for the presence of Clostridium difficile was performed using contact plates and cycloserine-cefoxitin-fructose with 0.1% sodium taurocholate agar. Clostridium difficile was isolated from 24 of 381 sites (6.3%). Growth was obtained from 4.5% (9/202) of sites sampled in the Large Animal Clinic, from 8.1% (13/160) of sites within the Small Animal Clinic, and from 20% (2/10) of sites sampled elsewhere. Fourteen of 21 strains tested produced toxins in vitro. A geographic association was found with areas in the large animal clinic where nosocomial C. difficile diarrhea in horses had previously been diagnosed. Several other sites with a potential for nosocomial transmission of the organism were identified. Areas from which C. difficile was isolated tended to be areas with high animal traffic, with increased chance of fecal contamination, and with rough, difficult to clean surfaces. This study documents the prevalence of this organism in the environment and its potential role in nosocomial disease.

show abstract

“…Τα λοιμώδη αίτια διάρροιας στο περιβάλλον της ΜΕΘ αυξάνουν τις πιθανότητες εμφάνισης επιπλοκών και τη μετάδοση του αιτιολογικού παράγοντα μεταξύ των ασθενών και του ιατρονοσηλευτικού προσωπικού 91. Οι διάρροιες στη ΜΕΘ συμβάλλουν στην παρατεταμένη νοσηλεία των ασθενών και οδηγούν σε μεγαλύτερη έκθεση σε ενδονοσοκομειακές λοιμώξεις με αποτέλεσμα την αύξηση της νοσηρότητας και της θνητότητας 75,92. Οι διάρροιες στη ΜΕΘ αυξάνουν τον μέσο όρο παραμονής των ασθενών κατά 8 ημέρες ενώ η αύξηση αυτή στους ηλικιωμένους ασθενείς είναι μεγαλύτερη 99,1077.…”

unclassified

Επίπτωση της λοίμωξης από Clostridium difficile στους βαρέως πάσχοντες ασθενείς της ΜΕΘ

Delga¹,

Δέλγα²

View full text Add to dashboard Cite

Το Clostridium difficile (κλωστηρίδιο το δύσκολο) είναι ένας από τους βασικούς παράγοντες που προκαλούν διάρροια στους ασθενείς της ΜΕΘ. Η επίπτωση του αυξάνεται εκθετικά και σχετίζεται κυρίως με τη χρήση αντιβιοτικών. Σκοπός- Μέθοδος:Σκοπός της παρούσας μελέτης ήταν η καταγραφή της επίπτωσης της λοίμωξης από C. difficile (CDI) στις ελληνικές ΜΕΘ η ταυτοποίηση παραγόντων κινδύνου που σχετίζονται με αυτή. Για το λόγο αυτό μια προοπτική πολυκεντρική μελέτη κοορτής σε βαρέως πάσχοντες ασθενείς, έλαβε χώρα σε 3 ΜΕΘ της Αθήνας από 1/1/2014 έως 31/12/2014 κατά την οποίαν κατεγράφη η επιβεβαιωμένη CDI και οι παράγοντες που σχετίζονταν μ΄αυτήν. Αποτελέσματα: Ανάμεσα σε 970 (100%) ασθενείς που ελέγχθηκαν τη περίοδο που έλαβε χώρα η μελέτη, 95 (9,79%) εμφάνισαν διάρροια. Κατά την είσοδο των ασθενών στη ΜΕΘ καταγράφηκαν τα δημογραφικά και κλινικά χαρακτηριστικά τους, οι γνωστοί προδιαθεσικοί παράγοντες για την εμφάνιση λοίμωξης ενώ ταυτόχρονα διεξήχθησαν διαγνωστικές εξετάσεις για την επιβεβαίωση της CDI βασιζόμενες στις πρόσφατες κατευθυντήριες οδηγίες. Η επίπτωση της CDI ήταν 1,3% (n=13). Η συνολική θνητότητα σε ασθενείς με διάρροια ή CDI και η θνητότητα που οφείλεται σε CDI ήταν 28%, 38.5% και 30.8% αντίστοιχα. Οι ασθενείς με CDI εμφάνιζαν υψηλότερη κλίμακα SOFA και ιστορικό προηγούμενης CDI ενώ δεν ταυτοποιήθηκε κανένας ανεξάρτητος παράγοντα που να σχετίζεται με την εμφάνιση CDI.Συμπεράσματα: Η CDI εμφανίζει χαμηλή επίπτωση στις ελληνικές ΜΕΘ αλλά παραμένει ένα σοβαρό πρόβλημα για τους βαρέως πάσχοντες. Στη παρούσα μελέτη δεν ταυτοποιήθηκε κανένας ανεξάρτητος παράγοντα που να σχετίζεται με την εμφάνιση CDI Λέξεις κλειδιά: C. difficile, ΜΕΘ

show abstract

Diarrhea Acquired in the Hospital

Cited by 47 publications

References 45 publications

Assessment of the incidence and etiology of nosocomial diarrhea in a medical ward in Iraq

Assessment of the incidence and etiology of nosocomial diarrhea in a medical ward in Iraq

Isolation of EnvironmentalClostridium Difficilefrom a Veterinary Teaching Hospital

Επίπτωση της λοίμωξης από Clostridium difficile στους βαρέως πάσχοντες ασθενείς της ΜΕΘ

Contact Info

Product

Resources

About