Diamagnetic lanthanide tris β-diketonate complexes with aryl-containing ligands as chiral NMR discriminating agents

Clark, Rebecca L.; Wenzel, Bradford T.; Wenzel, Thomas J.

doi:10.1016/j.tetasy.2013.01.021

Cited by 21 publications

(9 citation statements)

References 22 publications

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“…Camphor has been considered as an important source of natural terpenoid, which can be utilized as a desirable starting material for fabricating various valuable products including anesthetic, catalyst, shift reagent, antitumor, antibacterial, and so on. − In consideration of excellent biological compatibility and molecular rigidity of the camphor unit, our research group has been committed to the development of camphor-derived fluorescent probes in recent years, and these results manifested that the probe containing the camphor scaffold possesses some outstanding properties, such as excellent cell permeability, low cytotoxicity, high quantum yield, and good photostability. , Thus, it is quite promising to exploit a reliable fluorescent probe for Cys detection from natural and renewable camphor.…”

Section: Introductionmentioning

confidence: 99%

Novel Bis-Camphor-Derived Colorimetric and Fluorescent Probe for Rapid and Visual Detection of Cysteine and Its Versatile Applications in Food Analysis and Biological Imaging

Wang

Zhang

Liang

et al. 2022

J. Agric. Food Chem.

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A new colorimetric and fluorescent turn-on probe named 2,4-bis(camphor-3-methylene)phenylacrylate (BCP−Cys) was designed for highly sensitive and specific monitoring of cysteine (Cys). The probe BCP−Cys was strategically constructed by employing a new bis-camphor-derived scaffold (BCP-OH) as the fluorophore and an acrylate group as the recognition site and fluorescence quencher. The acrylate group of BCP−Cys could be exclusively cleaved by Cys and release the fluorophore BCP-OH, thereby causing a significantly enhanced red fluorescence and a naked-eye colorimetric change from colorless to yellow. The probe BCP−Cys exhibited promising sensing performances for Cys including large Stokes shift (184 nm), fast response time (<1 min), wide linear range (0−100 nM), and low detection limit (0.0728 μM). Moreover, the probe BCP−Cys could be utilized as a powerful tool for real-time determination of Cys levels within different food samples, such as onion, cabbage, broccoli, garlic, cauliflower, and bamboo sprout. In addition, this probe was also capable of imaging endogenous and exogenous Cys in living cells.

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Section: Introductionmentioning

confidence: 99%

Novel Bis-Camphor-Derived Colorimetric and Fluorescent Probe for Rapid and Visual Detection of Cysteine and Its Versatile Applications in Food Analysis and Biological Imaging

Wang

Zhang

Liang

et al. 2022

J. Agric. Food Chem.

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“…As a significant source of natural and renewable terpenoid, camphor commonly exists in a wide range of Lauraceae plants. In this case, camphor has been used as an ideal raw material to prepare a variety of valuable products such as catalysts, anesthetics, shift reagents, antibacteria, and antitumor. − Despite its common usage, few efforts have been made to develop it into fluorescent probes. More importantly, its rigid structure can severely limit intermolecular interactions and decrease the consumption of energy in collision progress, thereby improving the optical efficiency of camphor molecule greatly.…”

Section: Introductionmentioning

confidence: 99%

A Novel Camphor-Based “Turn-on” Fluorescent Probe with High Specificity and Sensitivity for Sensing Mercury(II) in Aqueous Medium and Its Bioimaging Application

Wang

Zhang

Yin

et al. 2020

ACS Sustainable Chem. Eng.

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Precise detection of Hg2+ in an ecological environment and biological system is of great importance. Hence, in this paper, we have constructed a simple fluorescent turn-on probe CP-Hg toward Hg2+ based on natural and renewable camphor. A significantly enhanced green fluorescence was clearly observed only with the participation of Hg2+ due to the Hg2+-mediated deprotection reaction of thioacetal. The probe CP-Hg could also sensitively detect Hg2+ with a detection limit of 19.3 nM and a large Stokes shift of 153 nm in a near-perfect aqueous solution. The reaction mechanism was fully analyzed through 1H NMR (proton nuclear magnetic resonance), ESI-MS (electrospray ionization mass spectrometry), and DFT (density functional theory) calculations. Moreover, the CP-Hg-coated test strips were successfully fabricated for naked-eye detection of Hg2+. Furthermore, the cell imaging experiment manifested that the probe CP-Hg is suitable for labeling intracellular Hg2+.

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“…Researchers designed a telescope to detect ameexcited emission from cesium, rubidium, and potassium salts at varying levels, allowing them to interpret chemical information encoded in the emission intensities from up to 1 mile away. 28 Two PUI-based groups have made contributions to spectroscopic investigations of chiral molecules, using complexing agents to discriminate between chiral compounds in NMR 29,30 and applying chiroptical spectroscopy of metal-ligand complexes to achieve sensitive, selective mercury detection. 31 Notably, all of the cited papers apply advanced spectroscopic techniques, exposing students to aspects of spectroscopy beyond the simple applications of UV-Vis and IR found in the typical undergraduate curriculum.…”

Section: Spectroscopymentioning

confidence: 99%

Analytical chemistry research at primarily undergraduate institutions: training tomorrow's investigators

Kovarik

2015

Anal. Methods

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Primarily undergraduate institutions (PUIs) are a unique training ground for young scientists who work closely with faculty on their research. Researchers at PUIs face a number of challenges, including balancing research and teaching responsibilities, obtaining sufficient funding for projects, and training students in their first research experiences. Faculty at PUIs deploy a variety of strategies to address these challenges, and the resulting research provides important benefits to faculty, students, the analytical chemistry community, and society. This perspective discusses these challenges and benefits in detail.Additionally, several vignettes describe how specific faculty members have established and maintained productive research programs at PUIs, and select publications since 2009 by PUI researchers are highlighted.

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Diamagnetic lanthanide tris β-diketonate complexes with aryl-containing ligands as chiral NMR discriminating agents

Cited by 21 publications

References 22 publications

Novel Bis-Camphor-Derived Colorimetric and Fluorescent Probe for Rapid and Visual Detection of Cysteine and Its Versatile Applications in Food Analysis and Biological Imaging

Novel Bis-Camphor-Derived Colorimetric and Fluorescent Probe for Rapid and Visual Detection of Cysteine and Its Versatile Applications in Food Analysis and Biological Imaging

A Novel Camphor-Based “Turn-on” Fluorescent Probe with High Specificity and Sensitivity for Sensing Mercury(II) in Aqueous Medium and Its Bioimaging Application

Analytical chemistry research at primarily undergraduate institutions: training tomorrow's investigators

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