Dialdehyde carbohydrates – Advanced functional materials for biomedical applications

Starch digestibility: How single, double, and multiple physicochemical modifications change nutritional attributes of starch?

“…The application of starch in its native form has been challenged by some obstacles, such as its insolubility in cold water, low gelatinization temperature, ease of syneresis, and the high tendency for retrogradation . Although the modification of starch through various physical and chemical approaches is able to improve its physicochemical characteristics, some drawbacks still exist (Falsafi et al, 2023). For instance, although the succinylated starches possess some advantages, such as high solubility in cold water, improved thickening power, high viscosity, increased paste clarity, retarded retrogradation, and freeze-thaw stability, they are unstable during shearing at high temperatures.…”

Alginate di-aldehyde-modified metal–organic framework nanocarriers as delivery platform and adjuvant in inactivated pseudorabies vaccination

“…The introduction of sodium alginate can increase the water solubility of ZIFs, which is beneficial for the delivery of formulated vaccines in vivo. 35 Considering this, in this work, we used alginate dialdehyde (short for ADA) to coat aminated ZIF-7/8 nanoparticles (NPs) through a Schiff base reaction 36 and prepared a complex nanoadjuvant (Scheme 1). In this process, the amino-group in ZIF-7/ 8 reacted with the aldehyde group in ADA to form a reversible imine bond (-CHQN-).…”

“…In this process, the amino-group in ZIF-7/ 8 reacted with the aldehyde group in ADA to form a reversible imine bond (-CHQN-). Furthermore, due to the reversibility of the imine bond, the alginate-modified ZIF NPs exhibited good stability in neutral or alkaline media, but underwent hydrolysis in an acidic environment, 36 which endowed the NPs with the ability to exhibit pH-responsive sustained-release drugs. 37 Our findings indicated that ZIF-7/8-ADA NPs exhibited a high antigen loading content and enhanced the antigen uptake efficiency by dendritic cells (DCs).…”

“…Considering this, in this work, we used alginate dialdehyde (short for ADA) to coat aminated ZIF-7/8 nanoparticles (NPs) through a Schiff base reaction 36 and prepared a complex nano-adjuvant (Scheme 1). In this process, the amino-group in ZIF-7/8 reacted with the aldehyde group in ADA to form a reversible imine bond (–CHN–).…”

Theoretical and Experimental Study of the Chemical Modification of Poly(epichlorohydrin) by Grafting Menthol

“…Functional polymers are produced by the integration of the identical or different functional groups into a polymer matrix. These polymers have attracted a lot of interest due to their numerous applications in recent years, such as in electrical [1,2] and electronic science [3,4], biotechnology [5,6], biochemistry [7,8], biomedical [9][10][11] (carriers of active ingredients), as well as in the agricultural field [12] (biocidal functions).…”