In a world increasingly saturated with data, scientific communication's success in reaching its target audience is linked to its ability to organize and represent information. Through semiotics concepts, this chapter explores the possibilities of information design as a set of tools for planning the exhibition of scientific content effectively. Information design is an area of knowledge that focuses on the human component's concern and the ergonomic aspects of visual communication. The chapter brings two case studies on infographics and on how information design is applied in popular scientific communication. The research will show that information design, associated with the precepts of plain language, can offer substantial contributions to the work of those who intend to disseminate science to non-specialized audiences.