Diagonal earlobe crease as a marker of the presence and extent of coronary atherosclerosis

Tranchesi, B; Barbosa, Vânia; Albuquerque, Cícero Piva de; Caramelli, Bruno; Gebara, Otávio; Filho, Raul Dias dos Santos; Nakano, Odila; Bellotti, Giovanni; Pileggi, F

doi:10.1016/0002-9149(92)90292-7

Cited by 48 publications

(32 citation statements)

References 14 publications

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“…These differences may be associated with genetic factors and racial differences. Tranchesi et al [25]reported results similar to ours, i.e. that patients with ELC, irrespective of age or sex, have a significantly increased prevalence of CAD, but they did not perform coronary angiography in their control group so there was no definite angiographic proof of absence of CAD in controls.…”

Section: Discussionsupporting

confidence: 74%

Bilateral Diagonal Earlobe Crease and Coronary Artery Disease: A Significant Association

et al. 2004

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Background: The association between the presence of diagonal earlobe crease (ELC) and coronary artery disease (CAD) still remains controversial. Objective: The aim of this study was to evaluate the association between bilateral ELC and CAD. Methods: 415 patients were examined for the presence or absence of bilateral ELC, angiographic evidence of CAD and coronary risk factors. The patients were divided into 2 groups according to angiographic evidence of CAD. Results: Bilateral ELC was significantly and positively correlated with CAD, hypertension, age, male gender, cigarette smoking and family history of CAD. The ELC was an independent variable for CAD. The observed sensitivity, specificity, positive predictive value and negative predictive value of the bilateral ELC for the diagnosis of CAD were in the following order: 51.3, 84.8, 89.4 and 41.2%. Conclusion: The presence of bilateral ELC was significantly associated with CAD and coronary risk factors. The bilateral ELC was an important dermatological indicator of CAD, and it might be a useful diagnostic tool in the clinical examination of patients.

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Section: Discussionsupporting

confidence: 74%

Bilateral Diagonal Earlobe Crease and Coronary Artery Disease: A Significant Association

et al. 2004

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“…Tranchesi Jr et al have also reported a significant association between ELC and CAD in quite a large sample of patients (1,424 patients), irrespective of patient's chronological age and sex, however, they did find the growing prevalence of ELC with advancing age. 15 Many other investigators have also reported similar findings. 11,13,14,19,20,25 Studies have shown that ELC has a reasonably high predictive value for cardiac events.…”

Section: Discussionmentioning

confidence: 55%

“…Since the first reporting of ELC by Frank in 1973, many other studies about ELC as a risk factor for CAD have been reported. 1,[9][10][11][12][13][14][15][16][17][18][19] While many studies have been reported regarding the relationship of ELC with CAD, very few have been reported on the correlation with atherosclerosis of the carotid artery. 2,3 Few have studied the correlation of ELC with carotid atherosclerosis, but they also have studied only the relationship with carotid IMT, not other indices of carotid artery ultrasonography such as PS and PN.…”

Section: Discussionmentioning

confidence: 99%

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Diagonal Ear-Lobe Crease is Correlated With Atherosclerotic Changes in Carotid Arteries

Shrestha

Ohtsuki

Nomura

et al. 2009

Circ J

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Background:The diagonal ear-lobe crease (ELC) is reported to be a marker of cardiovascular disease. Very few reports have assessed the relationship of ELC with atherosclerosis. This relationship is investigated here using a Japanese population. Methods and Results: A prospective cross-sectional study included 212 consecutive patients. Bilateral ear lobes were checked for the ELC and this was followed by carotid ultrasonography to measure the far wall common carotid artery intima-media thickness (CCA-IMT), plaque score (PS) and plaque number (PN). Patients with ELC had significantly higher carotid IMT than controls (0.90±0.24 vs 0.77±0.15, respectively, P<0.001). ELC presence correlated significantly with carotid IMT, PS, and PN (r=0.306, P<0.0001; r=0.198, P<0.008 and r=0.221, P<0.0001, respectively), and also with age, male sex and hypertension. ELC presence and absence in mild or no PS and moderate or severe PS subgroups was significant, with a chi-squared value of 7.59 (P<0.006). In multivariate regression analysis, ELC presence correlated with CCA-IMT independently. The odds ratio for the presence of ELC in patients with CCA-IMT of <0.8 mm vs patients with CCA-IMT of ≥0.8 mm (the median value) was 0.41 (95% confidence interval, 0.22-0.76). Conclusions:The present study showed an association between ELC and increased CCA-IMT, PS, and PN. (Circ J 2009; 73: 1945 -1949

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“…Benzer bir postmortem çal›flmada Kirkham ve arkadafllar› (18), kardiyovasküler sebepli ölümler ile DKLÇ aras›nda iliflki oldu¤u sonucuna varm›fllard›r. Çal›flmam›z›n bulgular›, vakalara uygulanan anjiografiler sonucunda RIA, RC ve ACD'de saptanan daralma yüzdeleri artt›kça DKLÇ görülme s›kl›¤›n›n artt›¤›n› göstermekte olup DKLÇ ve koroner arter hastal›¤› aras›nda anlaml› iliflkiler bildiren * Sat›r yüzdesi ** Sütun yüzdesi daha önceki çal›flmalar›n bulgular› ile uyumludur (2,3,4,8,9,13,14,20,(24)(25)(26)(27)(28). Baz› araflt›r›c›lar bu iliflkiyi yalanlamakta ve yafl›n, ço¤unlukla yafll› kiflilerde bulunan DKLÇ'nin ortaya ç›k›fl›n› etkileyebilece¤i üzerinde durmaktad›rlar (5,10,16,17,(29)(30)(31).…”

Section: Tartifimaunclassified

Ölüm Nedeninin Tespitinde Yardımcı Bir Bulgu Diagonal Kulak Lobu Çizgisi

Demirel¹,

Bahçecioğlu²,

Akar³

et al. 2005

Bull Leg Med

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Demirel B, Bahçelio¤lu M, Akar T, fienol E. Ölüm nedeninin tespitinde yard›mc› bir bulgu: Diagonal kulak lobu çizgisi.Adli T›p Bülteni, 2005;10(2):50-55.Koroner arter hastal›klar›, do¤al sebeplerle meydana gelen ölüm nedenlerinin bafl›nda gelmektedir. Bu hastal›klar›n yük-sek insidans ve mortalite oranlar›, bilinen risk faktörlerinden çok, olas› risk faktörlerinin araflt›r›lmas›n› gerekli k›lm›flt›r. Bir fizik muayene bulgusu olan diagonal kulak lobu çizgisi (DKLÇ), 1973 y›l›nda tan›mlanm›flt›r. Çal›flmam›zda, DKLÇ'nin, ölü muayenesi yapan hekim için ölüm nedeninin tespitinde yard›mc› bir bulgu olup olamayaca¤›n›n saptanmas› amaçlanm›flt›r.Çal›flmam›z›n bulgular›, vakalara uygulanan anjiografiler sonucunda; a. coronaria sinistra?n›n dallar› olan ramus interventricularis anterior (RIA) ve ramus circumflexus (RC) ile a. coronaria dextra'da (ACD) saptanan daralma yüzdeleri artt›kça DKLÇ görülme s›kl›¤›n›n da artt›¤›n› göstermektedir. Bu durum DKLÇ ve koroner arter hastal›klar› aras›nda anlaml› iliflkiler bildiren daha önceki çal›flmalar›n bulgular› ile uyumludur.Özellikle öyküye ulaflma olana¤› bulunmayan ve herhangi bir travmatik bulgu saptanmayan vakalarda DKLÇ'nin, ölü-mün koroner arter hastal›¤›ndan meydana geldi¤i yönünde destekleyici bir bulgu olarak muayeneyi yapan hekimin dikkatini çekmesi gereken bir iflaret oldu¤unu düflünmekteyiz.Anahtar kelimeler: Diagonal kulak lobu çizgisi, koroner arter hastal›¤›, ölü muayenesi.Coronary artery disease is a major cause of natural death. The high incidence and mortality of these diseases arised a need to investigate possible risk factors beyond well known. Diagonal ear lobe crease (DEC), was the physical sign, described in 1973. We investigated the possibility of DEC as a helpful predictive sign in the postmortem examination of forensic sudden death cases.The angiographic results revealed that whenever the percentages of the stenosis in left descending coronary artery, circumflex artery and right coronary artery increased, the incidence of the DEC did so accordingly. These results were correlated with the previous studies reporting significant correlation between coronary artery disease and the DEC.Particularly, in the absence of supportive medical history and without a physical sign of trauma, the presence of DEC could well be a supportive sign for the physician to consider the coronary artery disease as a cause of death.

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Diagonal earlobe crease as a marker of the presence and extent of coronary atherosclerosis

Cited by 48 publications

References 14 publications

Bilateral Diagonal Earlobe Crease and Coronary Artery Disease: A Significant Association

Bilateral Diagonal Earlobe Crease and Coronary Artery Disease: A Significant Association

Diagonal Ear-Lobe Crease is Correlated With Atherosclerotic Changes in Carotid Arteries

Ölüm Nedeninin Tespitinde Yardımcı Bir Bulgu Diagonal Kulak Lobu Çizgisi

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