Diagnostik und Therapie der chronischen Nierenerkrankung

Girndt, Matthias

doi:10.1007/s00108-017-0195-2

Cited by 24 publications

(13 citation statements)

References 37 publications

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“…Hypertension has been recognized as a primary modifiable contributor to cardiovascular and cerebrovascular diseases (1). In China, hypertension affects more than 270 million people, emerging as a major public health challenge (2)(3)(4). It was estimated that the direct costs caused by hypertension reached 210.3 billion Yuan in 2013, accounting for 6.61% of the total Chinese health-care expenditure (5).…”

Section: Introductionmentioning

confidence: 99%

Trends in Prevalence of Hypertension and Hypertension Phenotypes Among Chinese Children and Adolescents Over Two Decades (1991–2015)

Qian

Zhang

et al. 2021

Front. Cardiovasc. Med.

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Background: Hypertension is a leading cause of cardiovascular-related morbidity and mortality. Elevated blood pressure (BP) in children is related to long-term adverse health effects. Until recently, few studies have reported the secular trend and associated factors of hypertension phenotypes in Chinese children and adolescents.Methods: From the China Health and Nutrition Survey (CHNS) 1991–2015, a total of 15,143 records of children aged 7–17 years old were included. Following definitions of hypertension from the Chinese Child Blood Pressure References Collaborative Group, we estimated the prevalence of prehypertension, hypertension, stage 1 hypertension, stage 2 hypertension and its phenotypes (ISH, isolated systolic hypertension; IDH, isolated diastolic hypertension; SDH, combined systolic and diastolic hypertension). General estimation equation was used to analyze the trends in the prevalence of hypertension and hypertension phenotypes, and a multivariable logistic regression was constructed to explore the associated factors.Results: During 1991–2015, increasing trends were revealed in BP and hypertension prevalence (P < 0.001) in Chinese children and adolescents. For ISH, IDH and SDH, the age-standardized prevalence increased dramatically from 0.9 to 2.2%, from 6.2 to 14.1%, and from 1.4 to 2.9%, respectively (all P < 0.001). Adolescents aged 13–17 years (OR = 1.76, 95% CI: 1.56–1.97, P < 0.001), general obesity (OR = 2.69, 95% CI: 2.10-3.44, P < 0.001) and central obesity (OR = 1.49, 95% CI: 1.21–1.83, P < 0.001) were positively associated with hypertension, whereas the South region (OR = 0.65, 95% CI: 0.58–0.73, P < 0.001) was a negative factor. Furthermore, body mass index (BMI) and general obesity were linked to the presence of ISH, IDH and SDH. Age, waist circumference (WC) and central obesity were additionally associated with ISH, and sex, age, urban/rural setting, North/South region, WC and central obesity were additionally associated with IDH.Conclusion: BP levels and prevalence of hypertension and phenotypes increased dramatically in Chinese children and adolescents from 1991 to 2015. Regional discrepancy, demographic features, BMI, WC and overweight/obesity status were associated factors of hypertension among youths.

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Section: Introductionmentioning

confidence: 99%

Trends in Prevalence of Hypertension and Hypertension Phenotypes Among Chinese Children and Adolescents Over Two Decades (1991–2015)

Qian

Zhang

et al. 2021

Front. Cardiovasc. Med.

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“…According to statistics, the number of RF patients in the world is as high as 13.4%, and it is increasing year by year [ 3 , 4 ]. Early stage of RF is characterized by oliguria, anemia, etc., which is easily ignored by patients [ 5 ]. It is not difficult to cure early RF, and most patients can achieve a more rational state by controlling the etiology and diet [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

[Retracted] Effects of High‐Flux Dialysis Combined with Hemoperfusion on Serum GRP78 and miR‐495‐3p in Renal Failure Patients

Fan

et al. 2021

BioMed Research International

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Objective. This study was designed to probe into the changes and clinical significance of GRP78 and miR-495-3p in renal failure (RF) patients during high-flux dialysis (HFD) combined with hemoperfusion (HP). Methods. Sixty-five RF patients and 74 health check-ups who were admitted in our hospital from March 2015 to February 2017 were prospectively selected, and the related characteristics were retrospectively collected for analysis. GRP78 and miR-495-3p were detected in RF patients at admission (before treatment), 12 weeks after treatment (during treatment), 24 weeks after treatment (after treatment), and the control group at admission, and the relationship between the two and the occurrence, efficacy, and recurrence of RF was analyzed. Results. Before treatment, the GRP78 mRNA level in RF patients was higher than that in health check-ups, while the miR-495-3p level was lower ( P < 0.05 ). GRP78 mRNA in RF patients was lower than that before treatment and was the lowest after treatment. On the contrary, miR-495-3p was higher than that before treatment and was the highest after treatment ( P < 0.05 ). The two had a significant effect on predicting RF before treatment, efficacy of patients, and their recurrence after treatment (all P < 0.001 ). Conclusion. GRP78 decreased during the treatment of high-flux hemodialysis (HF-HD) combined with systemic HP in RF patients, while miR-495-3p increased. Both of them have a good reference value for RF occurrence, treatment results, and recurrence.

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“…Of these, patients receiving hemodialysis occupy about 90% of the total number of dialysis patients [6]. e main contributing factors of ESRD include chronic glomerulonephritis [7], hypertensive kidney damage [8], diabetic nephropathy [9], rheumatic kidney damage [10], and polycystic kidney [11], among which chronic glomerulonephritis is the leading chronic kidney disease worldwide and also the main cause of ESRD [12]. Furthermore, recent years have witnessed an increasing proportion of ESRD caused by diabetes, as the number of diabetic patients increases with the continuous improvement of living standards and changes in lifestyle and diet [13].…”

Section: Introductionmentioning

confidence: 99%

Study on the Application and Efficacy of Responsibility Nursing in Dialysis Care

Gao

Shi

et al. 2021

Journal of Healthcare Engineering

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Providing high-quality care to patients undergoing hemodialysis (HD) is a priority for nurses. The present study was conducted to explore the experiences of the quality of nursing care among patients, nurses, and caregivers in Yanghu Branch of Changzhou Second People’s Hospital, China. A total of 120 hemodialysis patients consecutively admitted to Yanghu Branch of Changzhou Second People’s Hospital were enrolled and divided into two groups according to the nursing method they received: control group (routine nursing) and experimental group (responsibility nursing). The two cohorts were observed and compared for alterations of adverse emotions and inflammatory factors, the incidence of complications, pre-and post-nursing sleep quality, life quality, and patients’ satisfaction with nursing. After nursing, the Self-Rating Anxiety/Depression Scale (SAS/DS) scores were lower in the experimental group (EG) than in the control group (CG) (both P < 0.05 ). Serum IL-6, hs-CRP, and TNF-α were decreased in both groups after nursing and were even lower in EG (both P < 0.05 ). EG had significantly improved sleep quality and life quality than CG, with a higher nursing satisfaction (all P < 0.05 ). This validates that the responsibility nursing for dialysis patients can validly mitigate patients’ negative emotions, improve their quality of life, and ensure high-quality dialysis effect, which is feasible for wide popularization and application in clinics.

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Diagnostik und Therapie der chronischen Nierenerkrankung

Cited by 24 publications

References 37 publications

Trends in Prevalence of Hypertension and Hypertension Phenotypes Among Chinese Children and Adolescents Over Two Decades (1991–2015)

Trends in Prevalence of Hypertension and Hypertension Phenotypes Among Chinese Children and Adolescents Over Two Decades (1991–2015)

[Retracted] Effects of High‐Flux Dialysis Combined with Hemoperfusion on Serum GRP78 and miR‐495‐3p in Renal Failure Patients

Study on the Application and Efficacy of Responsibility Nursing in Dialysis Care

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