Diagnostics and Treatment of Metastatic Cancers with Magnetic Nanoparticles

Abdeen, Sunitha; Pk, Praseetha

doi:10.4172/2155-983x.1000115

Cited by 15 publications

(5 citation statements)

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“…In 2013, Abdeen and Praseetha reported the generation of heat from the oscillating effect of iron oxide MNPs by the presence of magnetic field [65]. The generated heat works as the kinetic energy to considerably decrease the tumor size or cancerous tissue.…”

Section: Role Of Magnetic Nanoparticles In Lung Cancer Therapymentioning

confidence: 99%

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Rastogi¹,

Pandey²,

Pk³

et al. 2021

Preprint

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There are numerous challenges involved in the diagnosis and treatment of lung cancer. Globally, majority of people suffers from cancerous disease involving throat cancer, lung cancer, stomach cancer, cancerous brain tumor. Among these the most common ones is the lung cancer or lung carcinoma. The leading cause of the lung cancer is the smoking. Around 80% to 90% of deaths are caused due to Non-small cell lung cancer (NSCLC). The inadequate diagnostic techniques and low chances for the survival of lung cancer patients results from the lack of an early prognosis and incompetency in traditional therapies. However, such challenges involved in the prognosis and treatment of lung cancer are on decline with the progression in magnetic nanoparticle (MNP) technology. Many break-through discoveries and inventions have been made in the field of cancer therapy by using magnetic nanoparticles. The implication of nanotechnology has led to the recent advancement in nanomedicine field. This has encouraged the improvement in different therapeutic and diagnosis strategies employing nanotechnology. The generation of immense technological benefits for nanoparticles systems has been accredited to its remarkable nanoscale physico-chemical properties. This in turns provides the early detection of lung cancer and active drugs delivery for an improved theranostics strategy. The present review provides a general idea of the current progression in the therapeutic and prognosis purpose of magnetic nanoparticles. Further, we disclose the development in the lung cancer theranostics by functionalization of magnetic nanoparticles. The established importance of magnetic nanoparticles in the theranostics centers for lung cancer has been revealed in this paper. The challenges existing in the theranostics of lung cancer are addressed through the functioning of magnetic nanoparticles in the process.

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Section: Role Of Magnetic Nanoparticles In Lung Cancer Therapymentioning

confidence: 99%

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Rastogi¹,

Pandey²,

Pk³

et al. 2021

Preprint

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show abstract

“…The respiration mechanism of microbes depends on concentration of substrates, was restricted by these iron NPs via limiting the oxygen supply. 48 The concentration of substrates, pH and temperature of the incubated medium influenced the growth, mono-dispersion and dimensions of the formulated NPs. 49 In a similar study, Sharma et al revealed that the capping agent and incubation time period directly influenced the stability and size of formulated NPs, respectively.…”

Section: Nanoparticles Synthesis From Microbial Originmentioning

confidence: 99%

Eco-Friendly Greener Synthesis of Nanoparticles

et al. 2020

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The exploitation of naturally obtained resources like biopolymers, plant-based extracts, microorganisms etc., offers numerous advantages of environment-friendliness and biocompatibility for various medicinal and pharmaceutical applications, whereas hazardous chemicals are not utilized for production protocol. Plant extracts based synthetic procedures have drawn consideration over conventional methods like physical and chemical procedures to synthesize nanomaterials. Greener synthesis of nanomaterials has become an area of interest because of numerous advantages such as non-hazardous, economical, and feasible methods with variety of applications in biomedicine, nanotechnology and nano-optoelectronics, etc.

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“…For instance, the use of magnetic particles together with the MRI scans has greatly helped in increasing the image contrast (Ebrahimi et al 2016b). The contrast leads to the detection of various small cancer metastases that would otherwise be undetectable (Abdeen and Praseetha 2013). Also, the nanoparticles are used in the physical process of destroying the tumor tissues through the MNP hyperthermia have determined that nanoparticles have multiple applications in the diagnosis and treatment of different types of cancer (Colombo et al 2012) (Figure 2).…”

Section: Introductionmentioning

confidence: 99%

“…The technology uses the magnetic field to oscillate the iron oxide MNPs that creates heat (Abdeen and Praseetha 2013). The heat works in the form of kinetic energy to significantly reduce the size of the tumor or cancer tissue.…”

Section: Introductionmentioning

confidence: 99%

Magnetic nanoparticles in cancer diagnosis and treatment: a review

Karkan

Mohammadhosseini

Panahi

et al. 2016

Artificial Cells, Nanomedicine, and Biotechnology

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Diagnosis and treatment of lung cancer have been characterized with a variety of challenges. However, with the advancement in magnetic nanoparticle (MNP) technology, many challenges in the diagnosis and treatment of lung cancer are on the decline. The MNPs have led to many break-through in cancer therapy. This paper seeks to establish the role of MNPs in diagnosis and treatment of lung cancer. It proposes that the existing challenges in the diagnosis and treatment of lung cancer can be addressed through application of MNPs in the process.

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Diagnostics and Treatment of Metastatic Cancers with Magnetic Nanoparticles

Cited by 15 publications

References 0 publications

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Eco-Friendly Greener Synthesis of Nanoparticles

Magnetic nanoparticles in cancer diagnosis and treatment: a review

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