Diagnóstico diferencial de dengue y chikungunya en pacientes pediátricos

Calvo, Eliana; Coronel-Ruiz, Carolina; Velazco, Syrley; Velandia-Romero, Myriam L.; Castellanos, Jaime E.

doi:10.7705/biomedica.v36i0.2982

Cited by 13 publications

(13 citation statements)

References 32 publications

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“… Brooks [ 107 ] Santos, Brazil 2017 Case report 1 1 NA 27 IgM ELISA/IgM ELISA NM 40. Calvo [ 108 ] Girardot, Colombia Feb 2015 Cross sectional 8 4 50 0–10 IgM ELISA, PCR/PCR NM 41. Carrillo-Hernández [ 109 ] Norte de Santander, Colombia August 2015 – April 2016 Cross sectional 157 12 7.6 26.81 PCR/PCR NM 42.…”

Section: Resultsmentioning

confidence: 99%

Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review

et al. 2018

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BackgroundMalaria, Dengue and Chikungunya are vector borne diseases with shared endemic profiles and symptoms. Coinfections with any of these diseases could have fatal outcomes if left undiagnosed. Understanding the prevalence and distribution of coinfections is necessary to improve diagnosis and designing therapeutic interventions.MethodsWe have carried out a systematic search of the published literature based on PRISMA guidelines to identify cases of Malaria, Dengue and Chikungunya coinfections. We systematically reviewed the literature to identify eligible studies and extracted data regarding cases of coinfection from cross sectional studies, case reports, retrospective studies, prospective observational studies and surveillance reports.ResultsCare full screening resulted in 104 publications that met the eligibility criteria and reported Malaria/Dengue, Dengue/Chikungunya, Malaria/Chikungunya and Malaria/Dengue/Chikungunya coinfections. These coinfections were spread over six geographical locations and 42 different countries and are reported more frequently in the last 15 years possibly due to expanding epidemiology of Dengue and Chikungunya. Few of these reports have also analysed distinguishing features of coinfections. Malaria/Dengue coinfections were the most common coinfection followed by Dengue/Chikungunya, Malaria/Chikungunya and Malaria/Dengue/Chikungunya coinfections. P. falciparum and P. vivax were the commonest species found in cases of malaria coinfections and Dengue serotype-4 commonest serotype in cases of dengue coinfections. Most studies were reported from India. Nigeria and India were the only two countries from where all possible combinations of coinfections were reported.ConclusionWe have comprehensively reviewed the literature associated with cases of coinfections of three important vector borne diseases to present a clear picture of their prevalence and distribution across the globe. The frequency of coinfections presented in the study suggests proper diagnosis, surveillance and management of cases of coinfection to avoid poor prognosis of the underlying etiology.Electronic supplementary materialThe online version of this article (10.1186/s12889-018-5626-z) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review

et al. 2018

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“…Historically, Colombia is one of the countries most affected by dengue, chikungunya, and Zika in the Americas region with dengue cases being diagnosed and reported to the national surveillance system since 1950 [ 4 , 27 – 30 ]. Although confirmation of these arboviruses should be based upon a positive result from antigen, antibody, or virus detection and/or isolation, the majority of diagnosis in endemic and resource constraint settings is mostly based on clinical symptoms [ 1 , 12 , 13 , 31 ]. In Colombia, confirmation of probable cases is largely based on clinical diagnosis plus at least one serological positive test or an epidemiological link to a confirmed case 14 days prior to symptoms onset [ 32 , 33 ].…”

Section: Introductionmentioning

confidence: 99%

Assessing the reporting of Dengue, Chikungunya and Zika to the National Surveillance System in Colombia from 2014–2017: A Capture-recapture analysis accounting for misclassification of arboviral diagnostics

et al. 2021

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Background Chikungunya, dengue, and Zika are three different arboviruses which have similar symptoms and are a major public health issue in Colombia. Despite the mandatory reporting of these arboviruses to the National Surveillance System in Colombia (SIVIGILA), it has been reported that the system captures less than 10% of diagnosed cases in some cities. Methodology/Principal findings To assess the scope and degree of arboviruses reporting in Colombia between 2014–2017, we conducted an observational study of surveillance data using the capture-recapture approach in three Colombian cities. Using healthcare facility registries (capture data) and surveillance-notified cases (recapture data), we estimated the degree of reporting by clinical diagnosis. We fit robust Poisson regressions to identify predictors of reporting and estimated the predicted probability of reporting by disease and year. To account for the potential misclassification of the clinical diagnosis, we used the simulation extrapolation for misclassification (MC-SIMEX) method. A total of 266,549 registries were examined. Overall arboviruses’ reporting ranged from 5.3% to 14.7% and varied in magnitude according to age and year of diagnosis. Dengue was the most notified disease (21–70%) followed by Zika (6–45%). The highest reporting rate was seen in 2016, an epidemic year. The MC-SIMEX corrected rates indicated underestimation of the reporting due to the potential misclassification bias. Conclusions These findings reflect challenges on arboviruses’ reporting, and therefore, potential challenges on the estimation of arboviral burden in Colombia and other endemic settings with similar surveillance systems.

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“…Calvo y cols. 29 reportaron 8 casos de pacientes pediátri-cos con sospecha diagnóstica de dengue o Chikungunya con el objetivo de comparar el diagnóstico presuntivo basado en los hallazgos clínicos con el diagnóstico diferencial hecho mediante pruebas de laboratorio. En esta serie se incluyeron 8 casos, 7 de los cuales eran neonatos.…”

Section: Discussionunclassified

Dengue perinatal: Reporte de caso

Manzano-Núñez

Zapata

García‐Perdomo

et al. 2017

Rev. chil. pediatr.

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Palabras clave:Dengue, virus dengue, Trasmisión vertical Antígeno NonStructural Protein I ResumenIntroducción: El dengue perinatal es una patología de la que poco se sabe, los reportes disponibles describen riesgo de resultados perinatales adversos. Objetivo: Reportar un caso de dengue perinatal, como diagnóstico diferencial de sepsis neonatal, que debe tenerse en cuenta en zonas endémicas. Caso clínico: Recién nacido de una mujer de 23 años quien a las 36 semanas de gestación presentó cuadro de dengue con antígeno Non-Structural Protein 1 (NS1) positivo y anticuerpos anti-dengue negativos. Al sexto día de enfermedad dio a luz a un recién nacido sano, quien, al segundo día de vida, presentó fiebre sin otros hallazgos patológicos al examen físico, asociado a trombocitopenia severa (17.900 plaquetas/uL) y aumento de la proteína C reactiva, antígeno viral NS1 positivo e inmunoglobulina G (IgG) anti dengue positiva. Fue manejado con antibióticoterpia con ampicilina y gentamicina por protocolo de la institución para sepsis neonatal probable. El neonato mostró mejoría clínica, con estabilidad hemodinámica y aumento significativo de plaquetas, siendo dado de alta. Conclusiones: El dengue en el embarazo trae consigo el riesgo de resultados perinatales adversos, particularmente bajo peso al nacer y parto pre-término. Los hijos de madres diagnosticadas con dengue al final del embarazo deberían ser observados estrechamente con realización de hemograma seriado en los primeros días de vida, debido al riesgo de transmisión vertical. Keywords:Dengue; Dengue virus; Vertical transmission Non-Structural Protein I Antigen Abstract Introduction: Few reports are available about perinatal dengue, with controversial results in regards the risk of perinatal outcome. Objective: To report a case of perinatal dengue as a differential diagnosis with neonatal sepsis, which must be considered in endemic areas. Clinical case: Male newborn of a 23 year-old female, who presented a Non-Structural Protein 1 (NS1) antigen positive to dengue at 36 weeks of gestation and negative anti-dengue antibodies. At day six of the illness a healthy newborn

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Diagnóstico diferencial de dengue y chikungunya en pacientes pediátricos

Cited by 13 publications

References 32 publications

Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review

Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review

Assessing the reporting of Dengue, Chikungunya and Zika to the National Surveillance System in Colombia from 2014–2017: A Capture-recapture analysis accounting for misclassification of arboviral diagnostics

Dengue perinatal: Reporte de caso

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