Diagnostic significance of serum FGD5-AS1 and its predictive value for the development of cardiovascular diseases in patients with type 2 diabetes

Wang, Yongdi; Wang, Jian

doi:10.1186/s13098-022-00789-x

Cited by 3 publications

(1 citation statement)

References 31 publications

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“…Portable sensors are receiving significant and growing interest in healthcare management, especially for monitoring chronic diseases such as diabetes and chronic wounds. It has been noted that one of the major causes of mortality is diabetes related diseases, affecting 537 million people in 2021, a number that is expected to significantly grow in the coming years [1,2]. The increasing glucose levels in the world population denote the importance of developing new sensors which can monitor glucose levels in a cost-effective and simple manner.…”

Section: Introductionmentioning

confidence: 99%

Cu2O-Based Electrochemical Biosensor for Non-Invasive and Portable Glucose Detection

2022

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Electrochemical voltammetric sensors are some of the most promising types of sensors for monitoring various physiological analytes due to their implementation as non-invasive and portable devices. Advantages in reduced analysis time, cost-effectiveness, selective sensing, and simple techniques with low-powered circuits distinguish voltammetric sensors from other methods. In this work, we developed a Cu2O-based non-enzymatic portable glucose sensor on a graphene paste printed on cellulose cloth. The electron transfer of Cu2O in a NaOH alkaline medium and sweat equivalent solution at very low potential (+0.35 V) enable its implementation as a low-powered portable glucose sensor. The redox mechanism of the electrodes with the analyte solution was confirmed through cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy studies. The developed biocompatible, disposable, and reproducible sensors showed sensing performance in the range of 0.1 to 1 mM glucose, with a sensitivity of 1082.5 ± 4.7% µA mM−1 cm−2 on Cu2O coated glassy carbon electrode and 182.9 ± 8.83% µA mM−1 cm−2 on Cu2O coated graphene printed electrodes, making them a strong candidate for future portable, non-invasive glucose monitoring devices on biodegradable substrates. For portable applications we demonstrated the sensor on artificial sweat in 0.1 M NaOH solution, indicating the Cu2O nanocluster is selective to glucose from 0.0 to +0.6 V even in the presence of common interference such as urea and NaCl.

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Section: Introductionmentioning

confidence: 99%