Diagnostic relevance of spatial orientation for vascular dementia: A case study

Abstract

ABSTRACTSpatial orientation is emerging as an early and reliable cognitive biomarker of Alzheimer’s disease (AD) pathophysiology. However, no evidence exists as to whether spatial orientation is also affected in vascular dementia (VaD).Objective: To examine allocentric (map-based) and egocentric (viewpoint-based) spatial orientation in an early stage VaD case.Methods: A spatial test battery was administered following clinical and neuropsychological cognitive evaluation.Results: Despite the patient’s complaints…