Diagnostic Performance of Coronary Angiography by 64-Row CT

Miller, Julie M.; Rochitte, Carlos Eduardo; Dewey, Marc; Arbab‐Zadeh, Armin; Niinuma, Hiroyuki; Gottlieb, Ilan; Paul, Narinder; Clouse, Melvin E.; Shapiro, Edward P.; Hoe, John; Lardo, Albert C.; Bush, David E.; Roos, Albert de; Cox, Christopher; Brinker, Jeffery; Lima, João A.C.

doi:10.1056/nejmoa0806576

Cited by 1,640 publications

(973 citation statements)

References 27 publications

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“…37 Use of CTA allows for a noninvasive evaluation of the coronary arteries with a reported high diagnostic accuracy for obstructive CAD. 42,43 In a series of 51 women and 52 men, the diagnostic sensitivity and specificity was similar by sex at 85% and 99%, respectively. 44 An important limitation for CTA is the ionizing radiation that should be used cautiously in younger women because of a heightened lifetime risk of cancer.…”

Section: Cac Scoring and Ct Angiographymentioning

confidence: 90%

Noninvasive Diagnostic Techniques for Coronary Disease in Women

Vavas¹,

Hong²,

Rosen³

et al. 2012

Clinical Cardiology

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Significant advances in medical treatment, medical technology, and the focus on sex-specific research have contributed to a reduction in cardiovascular mortality in women. Despite these advances, coronary artery disease (CAD) is the leading cause of cardiovascular death of women in the Western world. In the past 2 decades, the focused research on women at risk for CAD has helped to clarify our understanding of some of the sex-specific factors that are important in the detection of CAD. In women, the detection and evaluation of physiologically significant CAD can be challenging. Many of the traditional tests that are designed to detect focal areas of coronary artery stenosis are less sensitive and specific in female patients, who have a greater burden of symptoms, higher atherosclerotic burden, and lower prevalence of obstructive coronary disease. In this article, we review the available evidence on the role of contemporary noninvasive diagnostic techniques in the evaluation of women with symptoms of CAD.

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Section: Cac Scoring and Ct Angiographymentioning

confidence: 90%

Noninvasive Diagnostic Techniques for Coronary Disease in Women

Vavas¹,

Hong²,

Rosen³

et al. 2012

Clinical Cardiology

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show abstract

“…Early studies comparing the diagnostic capabilities of CTCA with ICA often excluded patients with elevated baseline CS as a result of the negative impact of high CS on CTCA accuracy or the inability to assess the presence or absence of stenosis with increased calcification [2][3][4]. Studies which did include arterial segments with high levels of calcification usually denoted a significant decline in the diagnostic capability of the test.…”

mentioning

confidence: 99%

Coronary calcification: Achilles’ heel in the assessment for coronary artery disease in patients with symptomatic angina?

Makaryus

2009

Int J Cardiovasc Imaging

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“…Conversely, patients with high-risk coronary anatomy are more likely to benefit from coronary revascularization (18). There are very limited data supporting the use of cardiac CT to guide revascularization strategies (19). Patients who have test results consistent with high-risk CAD or uncontrolled symptoms are more likely to benefit from invasive coronary angiography.…”

Section: When Is Cardiac Ct Contraindicated?mentioning

confidence: 99%